Results 321 to 330 of about 172,036 (354)
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IgG N-glycans

2021
Glycosylation, one of the most common post-translational modifications in mammalian cells, impacts many biological processes such as cell adhesion, proliferation and differentiation. As the most abundant glycoprotein in human serum, immunoglobulin G (IgG) plays a vital role in immune response and protection. There is a growing body of evidence suggests
Si, Liu, Xin, Liu
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Counting glycans revisited

Journal of Mathematical Biology, 2013
We present an algorithm for counting glycan topologies of order n that improves on previously described algorithms by a factor n in both time and space. More generally, we provide such an algorithm for counting rooted or unrooted d-ary trees with labels or masses assigned to the vertices, and we give a "recipe" to estimate the asymptotic growth of the ...
Böcker, Sebastian, Wagner, Stephan
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Synthetic Glycan Microarrays

2016
Structurally diverse glycans are expressed by all animate beings and exert diverse biological functions through specific interactions with glycan binding proteins (GBPs). In humans, glycan-GBP interactions are implicated in many disease-relevant processes in development, infection and immune response to bacterial and viral pathogens. Recent progress in
Felix, Broecker, Peter H, Seeberger
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Hydrogel glycan microarrays

Analytical Biochemistry, 2005
The technology of hydrogel microchips manufacturing, which was developed previously for covalent immobilization of DNA and proteins, was applied for the preparation of glycochips and combined glyco/protein chips. Microchips consist of hydrogel drops separated with hydrophobic surface.
V I, Dyukova   +5 more
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Glycan Array Technology

2019
Glycan (or carbohydrate) arrays have become an essential tool in glycomics, providing fast and high-throughput data on protein-carbohydrate interactions with small amounts of carbohydrate ligands. The general concepts of glycan arrays have been adopted from other microarray technologies such as those used for nucleic acid and proteins.
Juana Elizabeth Reyes, Martinez   +2 more
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Natural glycan microarrays

Expert Review of Proteomics, 2010
Glycan microarrays are emerging as increasingly used screening tools with a high potential for unraveling protein-carbohydrate interactions: probing hundreds or even thousands of glycans in parallel, they provide the researcher with a vast amount of data in a short time-frame, while using relatively small amounts of analytes. Natural glycan microarrays
Lonardi, E.   +3 more
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Mass spectrometric glycan rearrangements

Mass Spectrometry Reviews, 2011
AbstractMass spectrometric rearrangement reactions have been reported for a large variety of compounds such as peptides, lipids, and carbohydrates. In the case of carbohydrates this phenomenon has been described as internal residue loss. Resulting fragment ions may be misinterpreted as fragments arising from conventional glycosidic bond cleavages ...
Wuhrer, M.   +2 more
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Glycans in Regeneration

ACS Chemical Biology, 2013
Glycans participate in many key cellular processes during development and in physiology and disease. In this review, the functional role of various glycans in the regeneration of neurons and body parts in adult metazoans is discussed. Understanding glycosylation may facilitate research in the field of stem cell biology and regenerative medicine.
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Synthetic plant glycans

Current Opinion in Chemical Biology, 2017
For more than a century the primary carbon source for the production of fuels, chemicals and many materials has been fossil resources. Recently, plant polysaccharides from non-food biomass have emerged as a promising renewable alternative that may displace a significant fraction of petroleum-derived products. As a food source, plant polysaccharides can
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Capturing glycans

Nature Reviews Microbiology, 2023
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