Results 221 to 230 of about 34,547 (259)

Computer models of albumin and haemoglobin glycation

Computer Methods and Programs in Biomedicine, 1990
Two first-order mathematical models were developed to mimic the glycation of haemoglobin (H) and albumin (A). The total concentrations of A and H were assumed to be constant. The responses of the two models to varying blood glucose level were compared.
S, Svacina, R, Hovorka, J, Skrha
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Difference of seasonal variation between glycated albumin and glycated haemoglobin

Annals of Clinical Biochemistry, 2018
Background Glycated albumin reflects 2–3-week glycaemic controls, and in addition to glycated haemoglobin, it has been used as a glycaemic control indicator. We presumed that glycated albumin also has seasonal variations and is related to temperature, similar to glycated haemoglobin.
Shu Meguro, Junichiro Irie, Yoshifumi Saisho   +2 more
exaly   +3 more sources

The relative extent of glycation of haemoglobin and albumin

Clinica Chimica Acta, 1987
The level of non-enzymatic glycation of a protein is thought to depend on the number of sites available for reaction, the half-life of the protein and the ambient concentration of glucose. Accordingly, the modification of two blood proteins with a similar number of potential sites but different survival times was examined in non-diabetic patients by ...
S, Olufemi, D, Talwar, D A, Robb
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The glycation of albumin: Structural and functional impacts

Biochimie, 2011
Oxidative stress and protein modifications are frequently observed in numerous disease states. Glucose constitutes a vital nutrient necessary to cellular oxygen metabolism. However, hyperglycemia-associated damage is an important factor in diabetes disorders.
Philippe, Rondeau, Emmanuel, Bourdon
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A Review of Glycated Albumin as an Intermediate Glycation Index for Controlling Diabetes [PDF]

Journal of Diabetes Science and Technology, 2008
Introduction: This article reviews glycated albumin (GA) as a potential intermediate-term glycation index to fill the gap between self-monitoring of blood glucose (SMBG) and hemoglobin A1c testing in diabetes management. The introduction gives an assessment of available short-, medium-, and long-term glycemic indicators.
H Vernon, Roohk, Asad R, Zaidi
exaly   +3 more sources

Albumin and Glycated Albumin

1995
Serum albumin is a single polypeptide chain protein of 66 000 Da molecular weight without associated carbohydrate. Glycation of albumin can be induced by prolonged exposure to elevated blood glucose levels, analogous to the induction of glycated haemoglobin.
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Minimal mathematical model for glycation of albumin

Clinical Biochemistry
Glycated albumin (GA) is often described as a reflection of glucose exposure over the past 2-4 weeks. We examined the scale of the operative interval for changes in %GA from the perspective of a theoretical model for GA formation, by simulating the time course of changes in %GA after changes in glucose.Probability of survival of albumin (A) was ...
Douglas F. Stickle, Gabriel J. DiNatale, Ross Molinaro   +2 more
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Glycated albumin and ratio of glycated albumin to glycated hemoglobin are good indicators of diabetic nephropathy in type 2 diabetes mellitus

Diabetes/Metabolism Research and Reviews, 2016
AbstractBackgroundWe investigated the association between serum levels of glycated albumin (GA), glycated hemoglobin (HbA1c), and GA:HbA1c ratio and the presence of diabetic nephropathy (DN) in patients with type 2 diabetes mellitus (T2DM).MethodsTwo hundred six consecutive patients with T2DM were enrolled from the endocrinology ward at Shengjing ...
Nana, Wang, Zhen, Xu, Ping, Han, Tiegang, Li   +3 more
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Glycation and drug binding by serum albumin

Accumulation of glycation products in patients with hyperglycaemic conditions can lead to their reaction with the proteins in the human system such as serum albumin, haemoglobin, insulin, plasma lipoproteins, lens proteins and collagen among others which have important biological functions. Therefore, it is important to understand if glycation of these
Anu, Jain, Nand, Kishore
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Thermal aggregation of glycated bovine serum albumin

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2010
Aggregation and glycation processes in proteins have a particular interest in medicine fields and in food technology. Serum albumins are model proteins which are able to self-assembly in aggregates and also sensitive to a non-enzymatic glycation in cases of diabetes.
Rondeau, P, NAVARRA, Giovanna, Cacciabaudo, F, LEONE, Maurizio, Bourdon, E, MILITELLO, Valeria   +5 more
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