Results 251 to 260 of about 130,285 (343)

Oxidative Stress, Advanced Glycation End Products (AGEs), and Neurodegeneration in Alzheimer's Disease: A Metabolic Perspective. [PDF]

Antioxidants (Basel)
Boccardi V, Mancinetti F, Mecocci P.
europepmc   +1 more source

The biology of the receptor for advanced glycation end products and its ligands

, 2000
Ann Marie Schmidt, Shi Du Yan, Shi Fang Yan, David M. Stern   +3 more
openalex   +1 more source

The Role of Micronutrients in Atherosclerosis: Mechanisms and Clinical Application

Journal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT Micronutrients, though required in relatively small quantities by the human body, are essential for maintaining normal physiological functions and play a crucial role in the prevention and management of various diseases. Atherosclerosis (AS) is a common chronic inflammatory condition that often presents without obvious symptoms in its early ...
Yuxin Ouyang, Weiwei Jiang, Xiongquan Long, Peng Mao, Pingping He, Xinping Ouyang   +5 more
wiley   +1 more source

Global transcriptional analysis of human FHs 74 Int intestinal epithelial cells after exposure to advanced glycation end products. [PDF]

PLoS One
Schwertner K, Basílio J, Hoffmann-Sommergruber K, Ellinger I, Geiselhart S.   +4 more
europepmc   +1 more source

A Role for High Mobility Group Box 1 (HMGB1) Release in the Pathogenesis of Gastroesophageal Reflux Disease

Neurogastroenterology &Motility, Volume 37, Issue 11, November 2025.
Incubation of esophageal epithelial cells with a weakly acidic (pH 5) bile salt (deoxycholic acid) induces translocation of HMGB1 from the nucleus to the cytosol, and its subsequent release from the cell. This process can be ameliorated by pre‐treatment with the antioxidant, curcumin.
Tom Leech, David Kelsell, Diana Blaydon, Philip Woodland, Madusha Peiris   +4 more
wiley   +1 more source

Improvement Effect and Mechanism of Hydroxytyrosol on Skin Aging Induced Advanced Glycation End Products. [PDF]

Nutrients
Fan R, Ma Y, Sun M, Zhang H, Han Y, Wang J, Zhu W, Zhang Z.   +7 more
europepmc   +1 more source

Mechanism of the Inhibitory Effect of OPB-9195 [(±)-2-Isopropylidenehydrazono-4-oxo-thiazolidin-5-ylacetanilide] on Advanced Glycation End Product and Advanced Lipoxidation End Product Formation

, 2000
Toshio Miyata, Yasuhiko Ueda, Koichi Asahi, Yuko Izuhara, Reiko Inagi, Akira Saitō, Charles van Ypersele de Strihou, Kiyoshi Kurokawa   +7 more
openalex   +1 more source

Histidine‐Containing Dipeptides in Obesity and Cardiometabolic Health: A Systematic Scoping Review

Obesity Reviews, Volume 26, Issue 11, November 2025.
ABSTRACT Background Histidine‐containing dipeptides (HCDs) have been reported to have anti‐inflammatory and antidiabetic properties. Yet, no previous reviews have examined the impact of HCDs on Type 2 diabetes (T2D) risk factors (e.g., obesity) and progression (e.g., microvascular and macrovascular complications).
Saeede Saadati, Robel Hussen Kabthymer, Giancarlo Aldini, Thilini R. Thrimawithana, Julie E. Stevens, Kathy Ngyuen, Arshad Majid, Simon M. Bell, Jack Feehan, Aya Mousa, Barbora de Courten   +10 more
wiley   +1 more source

A Simple Experimental Approach to Understanding the Formation of Advanced Glycation End Products. [PDF]

Cureus
Miyazaki K, Miyazaki K, Kaseda K.
europepmc   +1 more source

Decoding Glycosylation in Neurodegenerative Diseases: Mechanistic Insights and Therapeutic Opportunities

The FASEB Journal, Volume 39, Issue 20, 31 October 2025.
Graphical summary of glycosylation impairments in various neurodegenerative disorders. Among the diverse forms of glycosylation, the most extensively studied include N‐glycosylation, O‐glycosylation, and O‐GlcNAcylation. Aberrant glycosylation has been implicated in multiple neurodegenerative conditions.
Haihan Yu, Xing Chen, Yang Yang, Mengke Gu, Kaidi Ren, Ziqing Wei   +5 more
wiley   +1 more source