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The Interface of Oral and Brain Health: Current Insights Into the Bidirectional Relationship Between Alzheimer's Disease and Periodontitis

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Bidirectional Pathogenesis Between AD and Periodontitis. Periodontal pathogens reach the brain via hematogenous/trigeminal/oral–intestinal pathways, triggering neuroinflammation and Aβ plaques to drive AD. Conversely, AD disrupts bone homeostasis (via Aβ, endocrine/autonomic dysregulation) to aggravate periodontitis.
Weidong Zhang   +5 more
wiley   +1 more source

The hemoglobin glycation index stratifies heart failure phenotypes and in-hospital risk. [PDF]

open access: yesFront Endocrinol (Lausanne)
Lyu C   +8 more
europepmc   +1 more source

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