Results 61 to 70 of about 5,504,561 (298)

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen   +7 more
wiley   +1 more source

The Effect of Rice Variety and Parboiling on in vivo Glycemic Response

open access: yesTropical Agricultural Research, 2011
Improved and traditional rice varieties grown in Sri Lanka namely, Bg 300, Bg 352, Bg 358, Bg 406, LD 356, Rathkaral, Wedaheenati and Heendikwel were studied for their in vivo glycemic response.
PMHD Pathiraje   +3 more
doaj   +1 more source

Glycemic and insulinemic responses as determinants of appetite in humans [PDF]

open access: yesThe American Journal of Clinical Nutrition, 2006
The importance of the postprandial glycemic and insulinemic responses for appetite and energy intake (EI) is controversial.The aim of the study was to test the hypothesis that postprandial appetite sensations and subsequent EI are determined by postprandial glycemic and insulinemic responses after the intake of a range of breakfast meals.The study was ...
Flint, Anne   +7 more
openaire   +2 more sources

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

open access: yesAdvanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li   +11 more
wiley   +1 more source

The Acute Effects of Starch Sources on Glycemic Index, Glycemic Response, Insulinemic Response and Satiety-Related Hormones in Dogs [PDF]

open access: yes, 2018
This thesis investigated the glycemic index (GI) of single starch sources in dogs, including cooked white rice, cooked green lentils and white bread, as compared to a glucose control.
Rankovic, Alexandra
core   +1 more source

Probiotic Intervention in the Treatment of Diabetes Mellitus: A Review

open access: yesJournal of Pure and Applied Microbiology, 2022
Diabetes is a noncommunicable lifestyle condition that impacts millions of individuals worldwide. Diabetes is a physiological illness that affects several different organs in the human body.
Navya Sreepathi   +4 more
doaj   +1 more source

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

open access: yesAdvanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai   +12 more
wiley   +1 more source

Gut Microbial Signatures for Glycemic Responses of GLP-1 Receptor Agonists in Type 2 Diabetic Patients: A Pilot Study

open access: yesFrontiers in Endocrinology, 2022
BackgroundsGlucagon-like peptide-1 receptor agonist (GLP-1 RA) is probably one of more effective antidiabetic agents in treatment of type 2 diabetes mellitus (T2D).
Chih-Yiu Tsai   +12 more
doaj   +1 more source

Programmable Self‐Heating Microneedle Patch for on‐Demand Postprandial Glucose Management

open access: yesAdvanced Science, EarlyView.
A programmable self‐heating microneedle patch enables on‐demand, timed‐sequence insulin delivery via user‐triggered quadrant activation. Each activation generates localized heat that melts a phase‐change barrier, accelerating drug release. In diabetic rats, sequential quadrant activation counteracts four meal‐mimicking glucose spikes over 24 h without ...
Yang Zhao   +9 more
wiley   +1 more source

Immune Biomarkers of Islet Transplant Rejection Revealed by Synthetic Immunological Niche

open access: yesAdvanced Science, EarlyView.
A subcutaneous synthetic immunological niche (IN) enables serial, minimally invasive monitoring of immune responses after islet transplantation. Flow cytometry and transcriptomic profiling of the IN reveal immune‐cell programs associated with graft acceptance and distinct types of rejection.
Jyotirmoy Roy   +8 more
wiley   +1 more source

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