Results 61 to 70 of about 8,721 (181)

Myelin Impairment and Regeneration in the Central Nervous System: Molecular Mechanisms, Diseases, and Prospective Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Proper myelin formation is crucial for normal neural circuit function, while myelin deficiency can lead to neural circuit dysfunction and cognitive decline, notably in Alzheimer's disease and other central nervous system demyelinating disorders. This review summarizes central myelin's structure and function, demyelination biomarkers and pathological ...
Lihong Huang   +5 more
wiley   +1 more source

Different Substrate Selectivity and Product Patterns of Immobilized Thermophilic Lipases from Geobacillus stearothermophilus, Anoxybacillus flavithermus, and Thermomyces lanuginosus for Glyceryl Decanoate Synthesis

open access: yesChemEngineering
Lipases can catalyze synthesis reactions in a micro aqueous system, producing useful partial glycerides (mono- and diglycerides), and these compounds are commonly utilized in different products as surfactants.
Teif A. Najm   +2 more
doaj   +1 more source

Hydrolysis of primary and secondary esters of glycerol by pancreatic juice

open access: yesJournal of Lipid Research, 1968
The relative rates of hydrolysis of the secondary ester in glycerol 1,3-benzylidene 2-oleate and in glycerol 1,3-dihexadecyl ether 2-oleate, and of the primary and secondary esters in triolein were determined.
F.H. Mattson, R.A. Volpenhein
doaj   +1 more source

Pracaxi Oil as a Potential Inhibitor of Fat Bloom

open access: yesJournal of the American Oil Chemists' Society, Volume 103, Issue 9, Page 1005-1017, September 2026.
ABSTRACT Fat bloom is one of the major technological challenges faced by the chocolate industry, caused by the polymorphic transition from β2(V) to β1(VI) crystals in cocoa butter (CB). One strategy to slow down this polymorphic transition is the addition of lipids rich in very long chain fatty acids (VLCFA), such as behenic acid.
Victoria Marques Gropelli   +4 more
wiley   +1 more source

Synthesis and Biological Evaluation of a Lipophilic Vorinostat Prodrug

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
A series of lipid‐vorinostat conjugates (3a‐d) through acylation with short‐chain fatty acid chloride derivatives were synthesized. The compound 3d demonstrated improved cytotoxicity against A549 and 4T1 carcinoma cells. Mechanistic insight revealed that the prodrug 3d induced higher levels of caspase‐3/7 activation, reactive oxygen species (ROS), and ...
Navneet Thakur   +3 more
wiley   +1 more source

Characterization of Powdered Roasted Açaí Seeds (Euterpe oleracea Mart.): Impact on Bioactive Compounds and Nutritional Potential

open access: yesFood Science &Nutrition, Volume 14, Issue 9, September 2026.
Roasting enhanced the functional potential of açaí (Euterpe oleracea Mart.) seeds, yielding a fiber‐rich powder with relevant minerals and bioactive compounds. Both lipid and aqueous extracts showed high phenolic contents and antioxidant activity, while the lipid fraction provided vitamin E‐active compounds and valuable fatty acids.
Renata da Silva Magalhães   +9 more
wiley   +1 more source

Blood Biomarkers of Helicobacter pylori‐Infected Chronic Gastritis in Active Versus Stable Phases: A Clinical Indicator Analysis Combined With Proteomic and Metabolomic Investigations

open access: yesiMetaMed, Volume 2, Issue 3, September 2026.
Combining clinical data with serum proteomics and metabolomics, the HGB–CAPZB–acetic acid model was developed as a potential diagnostic index to distinguish the active and stable stages of Helicobacter pylori‐infected chronic gastritis, and the related mechanism was explored through multi‐omics.
Tiantong Jiang   +7 more
wiley   +1 more source

Metabolic feature profiling and metabolic vulnerability in acute lymphoblastic leukemia

open access: yesInterdisciplinary Medicine, Volume 4, Issue 5, September 2026.
For the first time, our study develops a novel metabolic classification and subtyping program, metabolic reprogramming‐based classifier for acute lymphoblastic leukemia, using internal PDT‐ALL‐2016 and external cohorts, which dissects metabolic profiling, clinical outcome, and therapeutic vulnerability for precision metabolic intervention in ALL ...
Xiaojie Liang   +13 more
wiley   +1 more source

Influence of a diet with chestnuts and sugar beet pulp on the lipid composition of “lacón gallego” (drycured pork foreleg)

open access: yesGrasas y Aceites, 2008
The objective of this study was to determine the influence of the inclusion of chestnuts and sugar beet pulp in pigs’ diets on the lipid composition of the external and internal muscles of dry-cured pork forelegs.
Ángel Cobos, Adán Veiga, Olga Díaz
doaj   +1 more source

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