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Metabolic labeling of glycerophospholipids

The approach of metabolic labeling provides an invaluable tool for elucidating previously unknown and poorly understood metabolic processes within cells. By introducing clickable versions of substrates into cells, the products of these biomolecule mimics can be conveniently tracked via post-derivatization of the clickable tag with a variety of reporter
Robert J, Maraski   +3 more
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Adaptive regulation of glycerophospholipid metabolism

Journal of Cell Science
ABSTRACT Lipid membranes form the essential barriers that compartmentalize life, separating intracellular processes from the external environment. To maintain cellular function and viability, both the plasma membrane and internal organelle membranes undergo continuous compositional and functional remodeling in response to ...
Tong Zhang, Yuan Wang, Cunqi Ye
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Glycerophospholipid profile in oncogene-induced senescence

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2012
Alterations in lipid metabolism and in the lipid composition of cellular membranes are linked to the pathology of numerous diseases including cancer. However, the influence of oncogene expression on cellular lipid profile is currently unknown. In this work we analyzed changes in lipid profiles that are induced in the course of ERBB2-expression mediated
Cristina, Cadenas   +16 more
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Mechanisms of glycerophospholipid homeostasis in mammalian cells

Progress in Lipid Research, 2011
The membranes of mammalian cells contain hundreds of different phospholipid species, a variety of glycolipids and cholesterol. While the reasons for such compositional diversity are not well established, they probably relate to a multitude of membrane-associated functions each of which sets specific requirements for the chemical and physical properties
Martin, Hermansson   +2 more
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Anionic glycerophospholipids in platelets from alcoholics

Drug and Alcohol Dependence, 1986
Studies on ethanol-exposed animals have revealed changes in anionic phospholipids in brain membranes. The intention of this study was to investigate whether there was a similar effect on man. Assuming platelets to be an adequate model for CNS synaptosomes, concentration and fatty acid composition of anionic phospholipids, phosphatidylserine (PS) and ...
C, Alling   +4 more
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Ethanolamine Glycerophospholipid Formation by Decarboxylation of Serine Glycerophospholipids in Myelinating Organ Cultures of Cerebellum

Journal of Neurochemistry, 1984
Abstract: Serine decarboxylation as a source of glycer‐ophospholipid ethanolamine is known to occur in mammals. However, early investigators failed to demonstrate the pathway in brain. In the present study serine is shown to be decarboxylated to glycerophospholipid ethanolamine in myelinating organ cultures of rat cerebellum up to 32 days in vitro ...
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The alkylacyl and alkenylacyl glycerophospholipids of human platelets

Thrombosis Research, 1983
The phospholipids of human platelets were isolated and analysed for their constituent 1-0-alkyl- and 1-0-(1'-alkenyl)glycerol species. The serine and inositol phospholipids contained only small amounts (0.5-1.6%) of both alkylacyl and alkenylacyl species; the ethanolamine phospholipids contained little alkylacyl (1.7%) but much more alkenylacyl (45.3%)
V, Natarajan   +3 more
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Enzymatic Conversions of Glycerophospholipids

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

Partial Synthesis of Glycerophospholipids

1987
Glycerophospholipids obtained from natural sources, that is from plant, animal or microbial cells, are complex mixtures of phospholipid classes, subclasses and species. It is extremely difficult if not impossible to isolate, with available technology, individual phospholipid species from such mixtures.
A. Hermetter, F. Paltauf
openaire   +1 more source

Dynamic Modulations of Sphingolipids and Glycerophospholipids in COVID-19

Clinical and Translational Medicine, 2022
Moriya Kyoji   +2 more
exaly  

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