Results 231 to 240 of about 398,460 (354)

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Gaze palsy in glycine receptor antibody-mediated autoimmune encephalitis: a case report. [PDF]

Acta Neurol Belg
Jiang W, Wang C, Xu Y, Ye Q.
europepmc   +1 more source

Mechanism of gating and partial agonist action in the glycine receptor. [PDF]

Cell, 2021
Yu J, Zhu H, Lape R, Greiner T, Du J, Lü W, Sivilotti L, Gouaux E.   +7 more
europepmc   +1 more source

Altered mnemonic functions and resistance to N-METHYL-d-Aspartate receptor antagonism by forebrain conditional knockout of glycine transporter 1

, 2009
Philipp Singer, Benjamin K. Yee, Joram Feldon, Takuji Iwasato, Shigeyoshi Itohara, Thomas Grampp, George A. Prenosil, Dietmar Benke, H. Möhler, Detlev Boison   +9 more
openalex   +1 more source

Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance

Advanced Science, EarlyView.
In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei, Junbin Chen, Chuang Liu, DanDan Liu, Meida Du, Shengfeng He, Wenyu Cheng, Vijai Bhadauria, You‐Liang Peng, Wangsheng Zhu   +9 more
wiley   +1 more source

Progressive Encephalomyelitis With Rigidity and Myoclonus With Glycine Receptor and GAD65 Antibodies: Case Report and Potential Mechanisms. [PDF]

Neurol Neuroimmunol Neuroinflamm
Winklehner M, Wickel J, Gelpi E, Brämer D, Rauschenberger V, Günther A, Bauer J, Serra AS, Jauk P, Villmann C, Höftberger R, Geis C.   +11 more
europepmc   +1 more source

Anti-glycine receptor antibody-positive progressive encephalomyelitis with rigidity and myoclonus initially presenting with one-sided stiff face: A case report. [PDF]

Front Neurol, 2022
Irie KI, Tateishi T, Moritaka T, Sakurada N, Kikuchi S, Taniwaki T.   +5 more
europepmc   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

A millisecond coarse-grained simulation approach to decipher allosteric cannabinoid binding at the glycine receptor α1. [PDF]

Nat Commun
Bartocci A, Grazzi A, Awad N, Corringer PJ, Souza PCT, Cecchini M.   +5 more
europepmc   +1 more source

Glycine receptor antibodies and coeliac disease-related neurological dysfunction. [PDF]

Cerebellum Ataxias, 2021
Kass-Iliyya L, Sarrigiannis PG, Sanders DS, Hadjivassiliou M.   +3 more
europepmc   +1 more source