Results 141 to 150 of about 43,679 (304)
Impact of Heparin on Endothelial Glycocalyx in Lung Grafts during Ex Vivo Lung Perfusion [PDF]
, 2021 Kentaro Noda +3 more
openalex +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
Mass Spectrometry Reviews, EarlyView.ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source
Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes. [PDF]
, 2020 The cell surface proteome, the surfaceome, is the interface for engaging the extracellular space in normal and cancer cells. Here we apply quantitative proteomics of N-linked glycoproteins to reveal how a collection of some 700 surface proteins is ...
Coon, Joshua +5 more
core
Vascular device interaction with the endothelium [PDF]
, 2008 Copyright @ 2008 Elsevier. This is the post-print version of the article.Cerebral stents and Intra Aortic Balloon Pumps (IABP) are examples of mechanical devices that are inserted into arteries to restore flows to clinically healthy states. The stent and
Atherton, MA +4 more
core +2 more sources
Genomics and Histopathology in Interstitial Cystitis/Bladder Pain Syndrome
Neurourology and Urodynamics, EarlyView.ABSTRACT Aims In April of 2025, a Global Consensus meeting on IC/BPS was held in Winston‐Salem, NC. The goal of this meeting was to establish global consensus in diagnostic criteria, phenotyping, treatment outcome assessment, and possible etiopathology in interstitial cystitis/bladder pain syndrome (IC/BPS).
Hannah Ruetten +4 more
wiley +1 more source
Proteomics Insights Into Lysosome Biogenesis and Maturation
PROTEOMICS, EarlyView.ABSTRACT Lysosomes constitute the main degradative organelle of most eukaryotic cells and are capable of breaking down a wide spectrum of biomolecules, including proteins, lipids, glycans, and DNA/RNA. They play crucial roles in the regulation of cellular homeostasis, acting as metabolic signaling centers for the correlation of nutrient availability ...
Katharina Hirn +2 more
wiley +1 more source
The Challenges of Vascular Implants: Regulatory Strategies and Biological Responses
Small Science, EarlyView.Implantable vascular devices are revolutionizing the management of cardiovascular diseases, such as heart failure, by enabling real‐time monitoring and individualized therapy. However, their potential is challenged by regulatory constraints and biological barriers, as device implantation into a vessel can trigger inflammation, thrombosis, and long‐term
Serena Babboni +5 more
wiley +1 more source
Regimes of Flow over Complex Structures of Endothelial Glycocalyx: A Molecular Dynamics Simulation Study [PDF]
, 2018 Flow patterns on surfaces grafted with complex structures play a pivotal role in many engineering and biomedical applications. In this research, large-scale molecular dynamics (MD) simulations are conducted to study the flow over complex surface ...
Feng, M, Jiang, XZ, Luo, KH, Ventikos, Y
core +2 more sources
Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation
Critical Care, 2019 BackgroundIntravenous fluids, an essential component of sepsis resuscitation, may paradoxically worsen outcomes by exacerbating endothelial injury. Preclinical models suggest that fluid resuscitation degrades the endothelial glycocalyx, a heparan sulfate-
J. Hippensteel +14 more
semanticscholar +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Ascites management is crucial for gynecological cancer patients requiring long‐term treatment. Cancer type‐specific differences may influence CART outcomes, but comparative data remain limited. This study evaluated CART efficacy in gynecological versus other cancers.
Nami Tamura +13 more
wiley +1 more source