Results 181 to 190 of about 43,679 (304)

Association Between Serum Syndecan 1 Levels and Metabolic Syndrome Parameters: A Comparative Cross‐Sectional Study

Endocrinology, Diabetes &Metabolism, Volume 8, Issue 6, November 2025.
The results revealed that men in the MetS+ HTN+ ALT+ group had significantly higher serum SDC1 levels than women (20.19 ± 10.56 vs. 11.82 ± 5.09 ng/mL, p = 0.020). Furthermore, in both the total study sample and the MetS+ HTN+ ALT+ group, SDC1 concentrations were positively correlated with diastolic blood pressure (r = 0.256, p = 0.021; r = 0.463, p ...
Shima Tavalaie, Saeed Darroudi, Niloofar Shabani, Artemis AzadAra, Ali Mottaghi‐Moghaddam, Mohammad Kalate Rahmani, Maryam Mohammadi‐Bajgiran, Gordon A. Ferns, Maryam Saberi‐Karimian, Majid Ghayour‐Mobarhan   +9 more
wiley   +1 more source

Two Sides of the Same Coin—Mechanistic Insight, Diagnostic Application and Therapeutic Translation of Bacterial and Host‐Derived Extracellular Vesicles

Journal of Extracellular Biology, Volume 4, Issue 11, November 2025.
ABSTRACT Extracellular vesicles (EVs) have gained increasing attention in recent years due to their pivotal role in both health and disease. Emerging from both eukaryotic and prokaryotic cells, EVs serve as essential mediators of intercellular communication, exceeding the simplistic interactions observed with individual molecules. In this comprehensive
Philipp Arnold, Fanni Annamária Boros, Jochen Mattner, Gerald Seidel, Chaofan Liu, Inga Viktoria Hensel, Jan Van Deun, Raphael Schwendner, Janina Müller‐Deile, Nina Sopel, Andreas Ramming, Mario R. Angeli, Simon Rauber, Cláudia Vilhena, Andreas Baur, Stefan Wirtz, Klaus Überla, Heiko Reutter, Linda‐Marie Mulzer, Alina C. Hilger, Friederike Zunke, Wei Xiang, Gregor Fuhrmann, Claudia Günther   +23 more
wiley   +1 more source

Lipopolysaccharide (LPS, endotoxin) of Proteus bacteria-chemical structure, serological specificity and the role in pathogenicity [PDF]

, 2008
Lipopolysaccharides (LPS) of Gram-negative bacteria are composed of three regions: О-specific chain (OPS), the core oligosaccharide and lipid A. All three regions of Proteus LPS were studied. The differences in the structure of OPS serve as the basis
Różalski, Antoni
core  

How gut sampling and microbial invasiveness/noninvasiveness provides mucosal immunity with a nonmolecular pattern means to distinguish commensals from pathogens: A review [PDF]

, 2008
Mucosal immunity distinguishes not only different microbial antigens but also separates those of pathogens from those of commensals. How this is done is unknown.
John R. Skoyles
core   +1 more source

Blockade of cannabinoid CB1 receptors potentiates the anti‐fibrotic effects mediated by SGLT2 inhibition in a mouse model of diabetic nephropathy

British Journal of Pharmacology, Volume 182, Issue 21, Page 5355-5377, November 2025.
Background and purpose Diabetic nephropathy (DN) is a common complication of diabetes. Current treatments include renin‐angiotensin‐aldosterone system (RAAS) blockers and sodium‐glucose co‐transporter 2 (SGLT2) inhibitors. The cannabinoid CB1 receptor is a potential therapeutic target.
Océane Pointeau, Awa Isma Ba, Audrey Geissler, Romain Barbosa, Abhishek Basu, Arif Muhammad, Marina Nivot, Maéva Loriot, Julia Leemput, Patricia Passilly‐Degrace, Sébastien Causse, Laurent Demizieux, Hélène François, Bruno Vergès, Jianmin Duan, Geneviève Gaucher, Michael Harvey, Pascal Degrace, Glenn Crater, Resat Cinar, Tony Jourdan   +20 more
wiley   +1 more source

Changes in microcirculation variables in an acute endotoxaemic equine model

Equine Veterinary Journal, Volume 57, Issue 6, Page 1623-1634, November 2025.
Abstract Background Microcirculation is the essential link between macrocirculation and cellular metabolism. Objectives To test our hypotheses that microcirculation variables will show a heterogeneous flow pattern during experimental endotoxaemia, and that fluid therapy and noradrenaline (NA) infusion will normalise altered microcirculation variables ...
Philipp K. Sauter, Barbara Steblaj, Sabine B. R. Kästner, Franz J. Söbbeler, Julia K. Reiners, Annette P. N. Kutter, Alvaro J. Gutiérrez Bautitsta, Stephan Neudeck   +7 more
wiley   +1 more source

Glycosaminoglycans as Polyelectrolytes: Charge, Interactions, and Applications

ChemBioChem, Volume 26, Issue 20, October 31, 2025.
Glycosaminoglycans (GAGs) are linear, anionic biopolymers with their functions tightly linked to their charge. This review approaches GAGs from a polyelectrolyte perspective, shedding light on how the distribution of sulfate groups and, thus, negative charges, governs their interactions with other biomolecules.
Gergo Peter Szekeres, Eunjin Moon, Johanna K. Elter, Bryce Roper, Jayachandran Narayanan Nair Kizhakkedathu, Matthias Ballauff, Rainer Haag, Kevin Pagel   +7 more
wiley   +1 more source

Glycocalyx shedding as a clinical biomarker in critical illness

Experimental and Molecular Pathology
The endothelial glycocalyx, a carbohydrate-rich layer lining the vascular endothelium, plays a critical role in maintaining vascular homeostasis by regulating permeability, leukocyte adhesion, and inflammatory signaling.
Ayako Inoda, Keiko Suzuki, Hiroyuki Tomita, Hideshi Okada   +3 more
doaj   +1 more source

Visual and Biochemical Evidence of Glycocalyx Disruption in Human Dengue Infection, and Association With Plasma Leakage Severity

, 2020
Phung Khanh Lam, Angela McBride, Duyen Huynh Thi Le, Trieu Trung Huynh, Hans Vink, Bridget Wills, Sophie Yacoub   +6 more
openalex   +1 more source

Glycocalyx and sepsis-induced alterations in vascular permeability [PDF]

, 2015
Cosimo Chelazzi, Gianluca Villa, Paola Mancinelli, Angelo Raffaele De Gaudio, Chiara Adembri   +4 more
openalex   +1 more source