Results 281 to 290 of about 43,679 (304)
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Journal of Intensive Care Medicine, 2022
Objective Sepsis is one of the main causes of morbidity and mortality worldwide. Microcirculatory impairment, especially damage to the endothelium and glycocalyx, is often not assessed.
J. Fernández-Sarmiento +7 more
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Objective Sepsis is one of the main causes of morbidity and mortality worldwide. Microcirculatory impairment, especially damage to the endothelium and glycocalyx, is often not assessed.
J. Fernández-Sarmiento +7 more
semanticscholar +1 more source
Mechanobiology of the abluminal glycocalyx
Biorheology, 2019Endothelial cells (ECs) sense the forces from blood flow through the glycocalyx, a carbohydrate rich luminal surface layer decorating most cells, and through forces transmitted through focal adhesions (FAs) on the abluminal side of the cell.This perspective paper explores a complementary hypothesis, that glycocalyx molecules on the abluminal side of ...
Peter J. Butler, Amit Bhatnagar
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The glycocalyx and immune evasion in cancer
The FEBS Journal, 2021In order to establish malignant lesions, tumors must first evade their detection by immune cells. Tumors achieve this by embellishing and tailoring their glycocalyx, a network of polysaccharides and glycosylated proteins that refracts the phagocytic efforts of myeloid cells, shrouds neoantigens and other ligands from cells of the acquired immune system,
Sina Ghasempour, Spencer A. Freeman
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Zhonghua yi xue za zhi, 2012
感染性休克是危重症患者主要死亡原因之一,而导致这种高病死率的病理生理学基础是微循环障碍所致的器官灌注不足.在其复杂的病理生理学过程中,内皮细胞的活化和功能障碍是导致微循环功能障碍的主要因素.最近有研究发现,在血管内皮细胞管腔侧广泛存在的多糖包被(glycocalyx)可作为内皮细胞损伤的新的生物学标志物,并可用于评价感染性休克的严重程度和指导液体复苏,同时,缺血再灌注损伤及肝素酶等对于多糖包被的破坏及糖皮质激素对其的保护作用也成为新的研究热点。
Xiao-chun Ma, Yi-ni Sun
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感染性休克是危重症患者主要死亡原因之一,而导致这种高病死率的病理生理学基础是微循环障碍所致的器官灌注不足.在其复杂的病理生理学过程中,内皮细胞的活化和功能障碍是导致微循环功能障碍的主要因素.最近有研究发现,在血管内皮细胞管腔侧广泛存在的多糖包被(glycocalyx)可作为内皮细胞损伤的新的生物学标志物,并可用于评价感染性休克的严重程度和指导液体复苏,同时,缺血再灌注损伤及肝素酶等对于多糖包被的破坏及糖皮质激素对其的保护作用也成为新的研究热点。
Xiao-chun Ma, Yi-ni Sun
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Glycocalyx in vivo measurement
Clinical Hemorheology and Microcirculation, 2017The endothelial glycocalyx (EG) lining the endoluminal surface of the capillaries has been proposed as a key component of the microcirculation and a major player in microvascular pathology. Recent advances in the understanding of its physiological role and clinical significance have been made upon the development of methods allowing EG assessment in ...
Christian Lehmann +6 more
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Glycocalyx Degradation and Endothelial Dysfunction in Vaso-Occlusion: A Review
International journal of medical sciences and pharma researchThe endothelial glycocalyx is a crucial component of vascular homeostasis, acting as a protective barrier and regulator of endothelial function. In sickle cell anemia (SCA), the degradation of the glycocalyx significantly contributes to endothelial ...
E. Obeagu
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The role of the glycocalyx in transvascular fluid shifts [PDF]
Transfusion Alternatives in Transfusion Medicine, 2010 SUMMARY Perioperative fluid management and fluid shifting have been main topics of debate in the recent years. Liberal fluid application is still a common practice and fluid overload believed to be a minor problem. Recent studies, however, have shown that liberal fluid management facilitates fluid shifts into the interstitial space especially in the
Tobias Kammerer +5 more
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Glycocalyx of Agmenellum quadruplicatum
Archives of Microbiology, 1980The marine cyanobacterium Agmenellum quadruplicatum was shown to possess an extracellular glycocalyx similar in structure to those surrounding other bacteria from a variety of natural environments. Thin sections of cells stained with ruthenium red and frozen-etched preparations of unfixed cells indicated the glycocalyx was a network of small fibrils ...
D. L. Balkwill, S. E. StevensJr.
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American Journal of Physiology-Heart and Circulatory Physiology, 2023
Vascular endothelial cells represent the first line of exposure to bacterial endotoxins. Here, we propose a novel therapeutic strategy using liposomes to deliver preassembled glycocalyx to vascular endothelial cell surface and consequently restore endothelial glycocalyx (EG).
Shinya Ishiko +4 more
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Vascular endothelial cells represent the first line of exposure to bacterial endotoxins. Here, we propose a novel therapeutic strategy using liposomes to deliver preassembled glycocalyx to vascular endothelial cell surface and consequently restore endothelial glycocalyx (EG).
Shinya Ishiko +4 more
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Glycocalyx Modifications in Acanthocephalans
Biology Bulletin, 2018Published reports and the author’s own data concerning the morphology of glycocalyx on the acanthocephalan tegument surface have been analyzed. Successive formation of up to six glycocalyx modifications that differ with regard to dimensions and certain structural characteristics has been shown to occur during the life cycle of these worms.
V. P. Nikishin, V. P. Nikishin
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