Results 21 to 30 of about 37,247 (212)

Molecular basis of impaired glycogen metabolism during ischemic stroke and hypoxia. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Ischemic stroke is the combinatorial effect of many pathological processes including the loss of energy supplies, excessive intracellular calcium accumulation, oxidative stress, and inflammatory responses.
Mohammed Iqbal Hossain   +2 more
doaj   +1 more source

Anti-diabetic potential of Psidium guajava leaf in streptozotocin induced diabetic rats

open access: yesPhytomedicine Plus, 2022
Background: Psidium guajava is a medicinal plant with antidiabetic properties and can be found growing in tropical and sub-tropical countries around the world.
Toluwani Tella   +2 more
doaj   +1 more source

PYGB Promoted Tumor Progression by Regulating Wnt/β-Catenin Pathway in Gastric Cancer

open access: yesTechnology in Cancer Research & Treatment, 2020
Gastric cancer is one of the most common gastrointestinal malignancy with high mortality in East Asia. Investigation of pathogenic mechanisms of gastric cancer is crucial to develop novel therapeutic strategies and identify new therapeutic candidates ...
Boning Xia MD, Ke Zhang MD, Chang Liu MD
doaj   +1 more source

Glycogenolysis Is Crucial for Astrocytic Glycogen Accumulation and Brain Damage after Reperfusion in Ischemic Stroke

open access: yesiScience, 2020
Summary: Astrocytic glycogen is an important energy reserve in the brain and is believed to supply fuel during energy crisis. However, the pattern of glycogen metabolism in ischemic stroke and its potential therapeutic impact on neurological outcomes are
Yanhui Cai   +13 more
doaj   +1 more source

Carbohydrate metabolism in diabetic rat’s heart – the effects of acetylsalicylic acid and heat preconditioning as HSP70 inducers

open access: yesMacedonian Veterinary Review, 2022
The myocardium of diabetic subjects displays reduced HSP70 protein level and weak myocardial protection. However, the heart possesses an ability to produce heat shock proteins (HSPs) after exposure to sublethal heat stress.
Mirsada Dervisevik   +5 more
doaj   +1 more source

Studies of liver phosphorylase in hepatic injuries. I. Alteration in enzyme activity [PDF]

open access: yes, 1978
Phosphorylase activities (total and a form) were determined in the livers of experimental hepatic injuries with carbon tetrachloride or galactosamine and the livers of patients with liver diseases.
Kobayashi, Michio
core   +1 more source

Lafora disease offers a unique window into neuronal glycogen metabolism [PDF]

open access: yes, 2018
Lafora disease (LD) is a fatal, autosomal recessive, glycogen-storage disorder that manifests as severe epilepsy. LD results from mutations in the gene encoding either the glycogen phosphatase laforin or the E3 ubiquitin ligase malin. Individuals with LD
Gentry, Matthew S.   +4 more
core   +2 more sources

Rag GTPases are cardioprotective by regulating lysosomal function. [PDF]

open access: yes, 2014
The Rag family proteins are Ras-like small GTPases that have a critical role in amino-acid-stimulated mTORC1 activation by recruiting mTORC1 to lysosome.
Guan, Kun-Liang   +8 more
core   +2 more sources

Is acetylation a metabolic rheostat that regulates skeletal muscle insulin action? [PDF]

open access: yes, 2015
Skeletal muscle insulin resistance, which increases the risk for developing various metabolic diseases, including type 2 diabetes, is a common metabolic disorder in obesity and aging.
LaBarge, Samuel   +2 more
core   +2 more sources

Symposium 10: Muscle

open access: yesRevista de la Sociedad Argentina de Diabetes, 2020
Symposium 10: Insulin resistance: from pathophysiology to treatment Muscle The main action of the insulin in the muscle is that of promoting the entrance of glucose to the myocyte through the glucose transporter type 4 (GLUT-4) and its storage as an ...
Juan M. Corvalán
doaj   +1 more source

Home - About - Disclaimer - Privacy