Results 21 to 30 of about 20,871 (172)

PYGB Promoted Tumor Progression by Regulating Wnt/β-Catenin Pathway in Gastric Cancer

Technology in Cancer Research & Treatment, 2020
Gastric cancer is one of the most common gastrointestinal malignancy with high mortality in East Asia. Investigation of pathogenic mechanisms of gastric cancer is crucial to develop novel therapeutic strategies and identify new therapeutic candidates ...
Boning Xia MD, Ke Zhang MD, Chang Liu MD
doaj   +1 more source

Glycogenolysis Is Crucial for Astrocytic Glycogen Accumulation and Brain Damage after Reperfusion in Ischemic Stroke

iScience, 2020
Summary: Astrocytic glycogen is an important energy reserve in the brain and is believed to supply fuel during energy crisis. However, the pattern of glycogen metabolism in ischemic stroke and its potential therapeutic impact on neurological outcomes are
Yanhui Cai, Haiyun Guo, Ze Fan, Xinlei Zhang, Di Wu, Wenhong Tang, Tingting Gu, Shiquan Wang, Anqi Yin, Liang Tao, Xunming Ji, Hailong Dong, Yan Li, Lize Xiong   +13 more
doaj   +1 more source

Synthesis, Kinetic and Conformational Studies of 2-Substituted-5-(β-d-glucopyranosyl)-pyrimidin-4-ones as Potential Inhibitors of Glycogen Phosphorylase

Molecules, 2020
Dysregulation of glycogen phosphorylase, an enzyme involved in glucose homeostasis, may lead to a number of pathological states such as type 2 diabetes and cancer, making it an important molecular target for the development of new forms of pharmaceutical
Konstantinos F. Mavreas, Dionysios D. Neofytos, Evangelia D. Chrysina, Alessandro Venturini, Thanasis Gimisis   +4 more
doaj   +1 more source

Hexokinase 2, glycogen synthase and phosphorylase play a key role in muscle glycogen supercompensation. [PDF]

PLoS ONE, 2012
BackgroundGlycogen-depleting exercise can lead to supercompensation of muscle glycogen stores, but the biochemical mechanisms of this phenomenon are still not completely understood.MethodsUsing chronic low-frequency stimulation (CLFS) as an exercise ...
José M Irimia, Jordi Rovira, Jakob N Nielsen, Mario Guerrero, Jørgen F P Wojtaszewski, Roser Cussó   +5 more
doaj   +1 more source

Anti-diabetic potential of Psidium guajava leaf in streptozotocin induced diabetic rats

Phytomedicine Plus, 2022
Background: Psidium guajava is a medicinal plant with antidiabetic properties and can be found growing in tropical and sub-tropical countries around the world.
Toluwani Tella, Bubuya Masola, Samson Mukaratirwa   +2 more
doaj   +1 more source

Design, Synthesis, and Use of Novel Photoaffinity Probes in Measuring the Serum Concentration of Glycogen Phosphorylase

Molecules, 2019
A procedure to measure the serum concentration of glycogen phosphorylase during acute myocardial infarction is presented. This method was based on the synthesis of photoaffinity probes, and used the semiquantitative protein electrophoretic mobility shift
Yuchao Zhang, Youde Wang, Zhiwei Yan, Chengjun Song, Guangxin Miao, Liying Zhang   +5 more
doaj   +1 more source

Liver type glycogen synthase (GYS2) and phosphorylase (PYGL) in largemouth bass (Micropterus salmoides): Cloning, characterization, and their transcriptional response to dietary carbohydrate content and resveratrol inclusion

Aquaculture Reports, 2021
Glycogen synthase (GS) and glycogen phosphorylase (GP) are considered as key enzymes involved in the regulation of glycogen synthesis and breakdown, respectively.
Jiajie Tao, Yu Zhang, Dixin Wang, Xueluan Jiang, Yijun Liu, Naisong Chen, Songlin Li   +6 more
doaj   +1 more source

THE EFFECTS OF ACUPUNCTURE AT“RENZHONG”POINT ON HEMORRHAGIC SHOCK'S MYOCARDIAL GLYCOGEN AND PHOSPHORYLASE A Histochemical Study

针刺研究, 1988
Fifty-six rabbits were used and divided into 5 groups—hemorrhagic shock(Bleeding 20ml/kg (?)ill the blood pressure dropped to 40-50 mmHg),acupuncture 1,acupuncture 2,sham operation and normal control.Two indexes were used—glycogen and phosphorylase,to ...
Xia Yaqin Wen Shen
doaj   +2 more sources

Valorization of Citrus Waste for Recovery of Nutritional and Bioactive Compounds: A Comprehensive Review

Future Postharvest and Food, EarlyView.
The various citrus wastes, including the citrus fruit peels, pulp remaining after extraction of juice, and seeds, are the sources of bioactive compounds. The waste parts of oranges, lemons, limes, grapefruits, and mandarins contain the bioactive compounds, flavonoids, ascorbic acid, essential oils, and carotenoids.
Monika, Rhythm Kalsi, Jasleen Kaur Bhasin, Rafeeya Shams, Kshirod Kumar Dash   +4 more
wiley   +1 more source

Carbohydrate metabolism in diabetic rat’s heart – the effects of acetylsalicylic acid and heat preconditioning as HSP70 inducers

Macedonian Veterinary Review, 2022
The myocardium of diabetic subjects displays reduced HSP70 protein level and weak myocardial protection. However, the heart possesses an ability to produce heat shock proteins (HSPs) after exposure to sublethal heat stress.
Mirsada Dervisevik, Suzana Dinevska-Kjovkarovska, Sasho Panov, Elena Rafailovska, Irena Celeska, Biljana Miova   +5 more
doaj   +1 more source