Results 161 to 170 of about 556,889 (346)

Concentration‐Based Analysis of Metal‐Induced Tau Fibrillar versus non‐fibrillar Aggregation: Implications for Neurotoxicity in Alzheimer's Disease

open access: yesChemistryOpen, EarlyView.
Tau protein aggregation and fibrillation have been examined in relationship to three metal ions in this study. The research was conducted to see the effects of Zn2+, Cu2+ and Fe3+ ions at different concentrations on tau′s conformation, cytotoxicity in SH‐SY5Y cells, and free thiol levels.
Mahzad Irandoust   +6 more
wiley   +1 more source

Clinical periodontal diagnosis

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi   +5 more
wiley   +1 more source

The role of rehabilitation across the continuum of liver disease from cirrhosis to transplantation and beyond: A narrative review

open access: yesPM&R, EarlyView.
Abstract Objective The authors' objective with this narrative review is to explore the impact of rehabilitative interventions at each stage of liver disease. Type Narrative review. Literature Survey Literature search conducted in Medline, Embase, and Google Scholar databases.
Laura Malmut   +5 more
wiley   +1 more source

Alternative nighttime nutrition regimens in glycogen storage disease type I: a controlled crossover study [PDF]

open access: green, 2015
Michel Hochuli   +5 more
openalex   +1 more source

Pharmacotherapy for Cirrhosis in Japan

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
As cirrhosis progresses from the compensated to the decompensated stage, liver disease‐related events such as varices, ascites, encephalopathy, sarcopenia, jaundice, and bleeding tendency, as well as liver carcinogenesis, can occur at a high rate. With the advent of new pharmacotherapies for cirrhosis in the last decade, liver fibrosis has been shown ...
Hiroki Nishikawa, Soo Ki Kim, Akira Asai
wiley   +1 more source

IL‐6 signaling in acute exercise and chronic training: Potential consequences for health and athletic performance

open access: yesScandinavian Journal of Medicine &Science in Sports, Volume 33, Issue 1, Page 4-19, January 2023., 2023
The cytokine interleukin‐6 (IL‐6) is involved in a diverse set of physiological processes. Traditionally, IL‐6 has been thought of in terms of its inflammatory actions during the acute phase response and in chronic conditions such as rheumatoid arthritis and obesity.
Dan Nash   +6 more
wiley   +1 more source

Liposome‐Polymer Nanoparticles Loaded with Copper Diethyldithiocarbamate and 6‐Bromo‐Indirubin‐3′‐Oxime Enable the Treatment of Refractive Melanoma

open access: yesSmall, EarlyView.
Cancer cells are exposed to heightened levels of endoplasmic reticulum stress and inflammation within the tumor microenvironment which can lead to therapeutic resistance. To address this issue, liposome‐polymer nanoparticles loaded with copper diethyldithiocarbamate (CuET), a potent inhibitor of the p97‐UFD1‐NPL4 protein complex, and the anti ...
Radu A. Paun   +4 more
wiley   +1 more source

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