Results 171 to 180 of about 556,889 (346)
Macromolecular crystallography at Elettra: current and future perspectives
The XRD2 beamline at Elettra‐Sincrotrone Trieste has been in operation since 2018 and is dedicated to macromolecular crystallography for both academic and industrial research, a role partially fulfilled, before 2018, by XRD1, a general‐purpose diffraction beamline.
Raghurama P. Hegde+13 more
wiley +1 more source
Impact of glycogen storage disease type I on adult daily life [PDF]
Sven F. Garbade+6 more
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Highlights: The contribution of winter and early spring‐available fruit (Aucuba japonica, Elaeagnus ×submacrophylla, and Viscum album) to the performance of D. suzukii depended on their P:C ratio and biophysical properties Even though D. suzukii performance was the lowest in A.
Jordy Larges+9 more
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Polyadenine insertion disrupting the G6PC1 gene in German Pinschers with glycogen storage disease type Ia (GSD1A) [PDF]
Matthias Christen+5 more
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Deciphering the Contribution of Circular RNAs to Age‐Related Decline in Sertoli Cell Survivor
Sertoli cell survival is regulated by circAbcb9‐ceRNET. Physiologically, the circAbcb9 sponge activity toward miR‐214‐3p ensures the expression of SOX8 and NOTCH2 targets, both crucial in maintaining SC homeostasis. The aging process negatively affects FUS‐dependent backsplicing activity in Sertoli cells leading to circAbcb9 downregulation, and in turn,
Francesco Manfrevola+11 more
wiley +1 more source
Orthotopic liver transplantation in children. Two-year experience with 47 patients [PDF]
During a 24-month period (May 1981 to May 1983), 47 pediatric patients (ranging in age from 7 months to 18 years) underwent orthotopic liver transplantation using cyclosporine and prednisone.
Gartner, JC+5 more
core
3D Mitochondrial Structure in Aging Human Skeletal Muscle: Insights Into MFN‐2‐Mediated Changes
Changes in mitochondrial structure and dynamics during aging provide a mechanism for the development of age‐related sarcopenia, a condition characterized by muscle mass loss. Through the creation of three‐dimensional models of mitochondria from quadriceps muscle tissue taken from old and young humans, a loss in mitochondrial complexity was observed to ...
Estevão Scudese+52 more
wiley +1 more source
Human asthenozoospermia: Update on genetic causes, patient management, and clinical strategies
Abstract Background In mammals, sperm fertilization potential relies on efficient progression within the female genital tract to reach and fertilize the oocyte. This fundamental property is supported by the flagellum, an evolutionarily conserved organelle, which contains dynein motor proteins that provide the mechanical force for sperm propulsion and ...
Emma Cavarocchi+5 more
wiley +1 more source
Abstract Background and objectives Epididymal transit renders key competence to mammalian spermatozoa for fertilizing eggs. Generally, the two paralogs of glycogen synthase kinase 3, GSK3α and GSK3β, functionally overlap except in testis and sperm. We showed that GSK3α is essential for epididymal sperm maturation and fertilization.
Mustfa Kabi+5 more
wiley +1 more source
Continuous electrocardiographic monitoring of fetal sheep heart during intermittent umbilical cord occlusions gradually leading to severe metabolic acidemia revealed several fetal arrhythmias including atrioventricular block, ventricular tachycardia, and ventricular fibrillation that would have gone unnoticed with current fetal monitoring systems ...
Juulia Lantto+10 more
wiley +1 more source