Results 191 to 200 of about 556,889 (346)

Screening and surveillance of hepatocellular carcinoma by serum des‐gamma‐carboxy prothrombin in patients with glycogen storage disease type Ia

open access: yesJIMD Reports
No sensitive tumor marker for hepatocellular carcinoma (HCC) is available for patients with glycogen storage disease type Ia (GSDIa), in whom alpha‐fetoprotein and carcino‐embryonic antigen levels often remain normal.
A. B. Schreuder   +5 more
doaj   +1 more source

Deep Transfer Learning for Kidney Cancer Diagnosis [PDF]

open access: yesarXiv
Many incurable diseases prevalent across global societies stem from various influences, including lifestyle choices, economic conditions, social factors, and genetics. Research predominantly focuses on these diseases due to their widespread nature, aiming to decrease mortality, enhance treatment options, and improve healthcare standards.
arxiv  

Pulmonary arterial hypertension and type-I glycogen-storage disease: the serotonin hypothesis [PDF]

open access: bronze, 2002
Marc Humbert   +11 more
openalex   +1 more source

Organoids in Haematologic Research: Advances and Future Directions

open access: yesCell Proliferation, EarlyView.
This review focuses on the advancements in organoid technology and its transformative role in haematological research, particularly in the modelling of haematopoietic tissues, blood diseases and drug development. It also offers an outlook on the future prospects of organoids in personalised medicine and the study of disease mechanisms.
Liangzheng Chang   +4 more
wiley   +1 more source

Large‐Scale Production of Expandable Hepatoblast Organoids and Polarised Hepatocyte Organoids From hESCs Under 3D Static and Dynamic Suspension Conditions

open access: yesCell Proliferation, EarlyView.
Under 3D suspension culture condition, the expandable hepatoblast organoids and mature polarised hepatocyte organoids were established by low concentration of Matrigel from human embryonic stem cells, which recapitulated the gene expression signatures and functions of primary human hepatoblast and hepatocytes.
Haibin Wu   +14 more
wiley   +1 more source

Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals

open access: yesCell Proliferation, EarlyView.
One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye   +6 more
wiley   +1 more source

Membraneless Organelles and Phase Separation in Tumours: Mechanisms and Prospects

open access: yesCell Proliferation, EarlyView.
The Salient and Novel Findings: This article summarises the latest research advancements in phase separation within tumours, with a particular focus on the role and molecular mechanisms of liquid–liquid phase separation (LLPS) in tumour progression.
Hao Yang   +3 more
wiley   +1 more source

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