No sensitive tumor marker for hepatocellular carcinoma (HCC) is available for patients with glycogen storage disease type Ia (GSDIa), in whom alpha‐fetoprotein and carcino‐embryonic antigen levels often remain normal.
A. B. Schreuder+5 more
doaj +1 more source
Deep Transfer Learning for Kidney Cancer Diagnosis [PDF]
Many incurable diseases prevalent across global societies stem from various influences, including lifestyle choices, economic conditions, social factors, and genetics. Research predominantly focuses on these diseases due to their widespread nature, aiming to decrease mortality, enhance treatment options, and improve healthcare standards.
arxiv
Pulmonary arterial hypertension and type-I glycogen-storage disease: the serotonin hypothesis [PDF]
Marc Humbert+11 more
openalex +1 more source
Organoids in Haematologic Research: Advances and Future Directions
This review focuses on the advancements in organoid technology and its transformative role in haematological research, particularly in the modelling of haematopoietic tissues, blood diseases and drug development. It also offers an outlook on the future prospects of organoids in personalised medicine and the study of disease mechanisms.
Liangzheng Chang+4 more
wiley +1 more source
Increased occurrence of cleft lip in glycogen storage disease type II (GSDII): Exclusion of a contiguous gene syndrome in two patients by presence of intragenic mutations (Am J Med Genet 85: 5–8(1999)) [PDF]
Maryann L. Huie+4 more
openalex +1 more source
Portal Diversion: Treatment for Glycogen Storage Disease and Hyperlipemia [PDF]
Putnam, CW, Starzl, TE
core +1 more source
Under 3D suspension culture condition, the expandable hepatoblast organoids and mature polarised hepatocyte organoids were established by low concentration of Matrigel from human embryonic stem cells, which recapitulated the gene expression signatures and functions of primary human hepatoblast and hepatocytes.
Haibin Wu+14 more
wiley +1 more source
Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals
One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye+6 more
wiley +1 more source
Membraneless Organelles and Phase Separation in Tumours: Mechanisms and Prospects
The Salient and Novel Findings: This article summarises the latest research advancements in phase separation within tumours, with a particular focus on the role and molecular mechanisms of liquid–liquid phase separation (LLPS) in tumour progression.
Hao Yang+3 more
wiley +1 more source
Glycogen Storage Disease Type I (Von Gierke disease): Report of Two Cases with Severe Dyslipidemia. [PDF]
Ballavenuto JMA+2 more
europepmc +1 more source