Glycogen synthase isoforms in Synechocystis sp. PCC6803: identification of different roles to produce glycogen by targeted mutagenesis. [PDF]
PLoS ONE, 2014 Synechocystis sp. PCC6803 belongs to cyanobacteria which carry out photosynthesis and has recently become of interest due to the evolutionary link between bacteria and plant species.
Sang-Ho Yoo +4 more
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Glycogen Metabolism and Its Role in Growth and Encystation in Entamoeba histolytica
Life, 2023 Entamoeba histolytica is a parasitic protozoan that causes diarrheal disease in approximately 100 million people worldwide every year. E. histolytica has two forms, the growing trophozoite and the infectious cyst.
Jordan Wesel, Cheryl Ingram-Smith
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Interaction between glycogenin and glycogen synthase [PDF]
Archives of Biochemistry and Biophysics, 2006 Glycogen synthase plays a key role in regulating glycogen metabolism. In a search for regulators of glycogen synthase, a yeast two-hybrid study was performed. Two glycogen synthase-interacting proteins were identified in human skeletal muscle, glycogenin-1, and nebulin.
Peter J. Roach +2 more
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Shared control of hepatic glycogen synthesis by glycogen synthase and glucokinase [PDF]
Biochemical Journal, 2000 We have used recombinant adenoviruses (AdCMV-RLGS and AdCMV-GK) to overexpress the liver isoforms of glycogen synthase (GS) and glucokinase (GK) in primary cultured rat hepatocytes. Glucose activated overexpressed GS in a dose-dependent manner and caused the accumulation of larger amounts of glycogen in the AdCMV-RLGS-treated hepatocytes.
Joan J. Guinovart +2 more
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Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization.
Genes & Development, 1998 The activities of cyclin D-dependent kinases serve to integrate extracellular signaling during G1 phase with the cell-cycle engine that regulates DNA replication and mitosis. Induction of D-type cyclins and their assembly into holoenzyme complexes depend
J. Diehl, M. Cheng, M. Roussel, C. Sherr
semanticscholar +1 more source
Aeromonas surface glucan attached through the O-antigen ligase represents a new way to obtain UDP-glucose. [PDF]
PLoS ONE, 2012 We previously reported that A. hydrophila GalU mutants were still able to produce UDP-glucose introduced as a glucose residue in their lipopolysaccharide core. In this study, we found the unique origin of this UDP-glucose from a branched α-glucan surface
Susana Merino +5 more
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[6]-Gingerol, from Zingiber officinale, potentiates GLP-1 mediated glucose-stimulated insulin secretion pathway in pancreatic β-cells and increases RAB8/RAB10-regulated membrane presentation of GLUT4 transporters in skeletal muscle to improve hyperglycemia in Leprdb/db type 2 diabetic mice [PDF]
, 2017 This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give ...
Akhter, Farjana +9 more
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Journal of Biological Chemistry, 2015 Background: Glycogen synthase kinase-3 (GSK3) inhibition promotes apoptosis of pancreatic cancer cells. Results: GSK3 inhibition concomitantly triggers a prosurvival autophagic response.
B. Marchand +4 more
semanticscholar +1 more source
Medicinal Research Reviews, Volume 43, Issue 1, Page 237-287, January 2023., 2023 Abstract The transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) is considered the master regulator of the phase II antioxidant response. It controls a plethora of cytoprotective genes related to oxidative stress, inflammation, and protein homeostasis, among other processes.
Enrique Crisman +6 more
wiley +1 more source
The role of glycogen phosphorylase in glycogen biogenesis in skeletal muscle after exercise
Sports Medicine and Health Science, 2023 Initially it was believed that phosphorylase was responsible for both glycogen breakdown and synthesis in the living cell. The discovery of glycogen synthase and McArdle's disease (lack of phosphorylase activity), together with the high Pi/glucose 1-P ...
Abram Katz
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