Glycogen and Glycosylation: Friends or Foes? [PDF]
Konada RSR, Osborn J, Mitra S.
europepmc +1 more source
Review of Congenital Myasthenic Syndrome Caused by Pathogenic Variants in GFPT1
ABSTRACT Glutamine:fructose‐6‐phosphate transaminase 1 (GFPT1) catalyzes the first and rate‐limiting step of the hexosamine biosynthetic pathway (HBP) to generate UDP‐GlcNAc. GFPT1 exon 9 is specifically spliced in in striated muscles, which makes a long isoform of GFPT1 (GFPT1‐L).
Kinji Ohno +5 more
wiley +1 more source
Low-Molecular-Weight Polyols as Key Factors in Sulfur- and Borate-Mediated Protomembrane Formation Before the RNA World. [PDF]
Dembitsky VM.
europepmc +1 more source
Donor‐induced conformational gating and substrate‐assisted catalysis in α‐1,3‐galactosyltransferase
Abstract Retaining glycosyltransferases catalyze the formation of stereochemically conserved glycosidic bonds through mechanisms that remain debated. Using bovine α1,3‐galactosyltransferase (α3GalT) as a model, we combine mutagenesis, equilibrium unfolding, kinetics, and molecular dynamics simulations to understand how donor‐induced loop ordering ...
Javier A. Linares‐Pastén +1 more
wiley +1 more source
The α-Gal Epitope (Galα1-3Galβ1-4GlcNAc) as Therapeutic Agent in Cancer Immunotherapy, Vaccine Effectiveness Amplification and Injured Tissue Regeneration. [PDF]
Galili U.
europepmc +1 more source
ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi +12 more
wiley +1 more source
Editorial: The role of glycolipids and sphingolipids in the differentiation and function of innate immune cells. [PDF]
Iwabuchi K, Tsuji M, Kasahara K.
europepmc +1 more source
Response surface optimization identified 60% microwave power and 40 s as a balanced condition for recovering bioactive compounds from Arisaema schimperianum tuber. LC–MS/MS profiling revealed diverse metabolites, while freeze‐drying best preserved thermolabile compounds, highlighting an effective strategy for maximizing extraction efficiency and ...
Gezahegn Abawa Zeleke +2 more
wiley +1 more source
Glycocalyx at the host-virus interface: a double-edged sword in virus infection and tissue damage. [PDF]
Tiwari V +7 more
europepmc +1 more source
Multi‐omics insights into salinity tolerance in African bermudagrass
Abstract African bermudagrass (Cynodon transvaalensis Burtt‐Davy) is a key parent species used to produce interspecific hybrid bermudagrass (Cynodon dactylon × C. transvaalensis). Due to the increasing use of non‐potable water for landscape irrigation, salt stress has become a major concern in the turfgrass industry.
Prabha Adhikari +7 more
wiley +1 more source

