Results 151 to 160 of about 37,889 (264)

Myocardial Lipid Metabolism Imbalance: The Pathological Core and Novel Diagnostic‐Therapeutic Directions of Cardiovascular Diseases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
In cardiac cells, Plin5/AMPK regulate lipid homeostasis; excess CD36‐mediated uptake drives lipotoxicity, mitochondrial dysfunction, and CVDs (e.g., heart failure). Biomarkers (ApoB/ApoA‐1) and therapies (SGLT2 inhibitors) target this cascade. ABSTRACT Cardiac lipid metabolism is fundamental to myocardial energy homeostasis, with fatty acid oxidation ...
Peiyun Xie, Qun Zeng, Hongrui Wang, Meihua She   +3 more
wiley   +1 more source

Fluorogenic Coupled Assays Reveal Catalytic Properties, Inhibition Constants and Cellular Location of Mucin‐Active Carbohydrate Sulfatases

Angewandte Chemie, Volume 138, Issue 30, 20 July 2026.
We report plate‐based coupled assays to rapidly and quantitatively determine the activity and selectivity of mucin‐active carbohydrate sulfatases. This fluorogenic assay further enables inhibitor identification and allows determination of (sub‐)cellular location. ABSTRACT Sulfated glycans play a central role in human health and influence cell signaling,
Charles W. E. Tomlinson, Madouc D. Bergers, David N. Bolam, Ana S. Luis, Alan Cartmell, Zachary Armstrong   +5 more
wiley   +2 more sources

Influence of Sugar Headgroup on the Self-Assembly of Bioinspired Anionic Glycolipids. [PDF]

Langmuir
Valentini G, Patiño-Agudelo ÁJ, de Abreu Furtado Garcia PR, Loh W.   +3 more
europepmc   +1 more source

Pathogenesis of Tuberculosis: Interplay Between Host Antituberculosis Immunity and Immune Evasion Strategies of Mycobacterium Tuberculosis

MedComm, Volume 7, Issue 8, August 2026.
Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang, Ying Liu, Yilin Hou, Hongxia Niu   +3 more
wiley   +1 more source

Highly Potent Th1-Type NKT Cell Agonists as Immunotherapeutic Agents via Conformational Restriction Design. [PDF]

JACS Au
Wen Y, Wu YH, Sun QN, Wang EY, Luo MQ, Fu ZR, Zhou Z, Mei DX, Guo J.   +8 more
europepmc   +1 more source

Bacterial Glycolipids

Bacteriological Reviews, 1970
openaire   +2 more sources

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, Volume 26, Issue 8, Page 9-28, August 2026.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Bifunctional glycolipids targeting TLR4·MD-2 and short pentraxins. [PDF]

RSC Chem Biol
Zucchetta D, Nuschy L, Gumpelmair S, Steinberger P, Wilson I, Heine H, Zamyatina A.   +6 more
europepmc   +1 more source

Quantum‐Capacitance Biosensing Enables Real‐Time Monitoring of Naxitamab for Therapeutic Response Stratification in Neuroblastoma

Small Science, Volume 6, Issue 8, August 2026.
Quantum‐capacitance biosensing enables real‐time monitoring of naxitamab in patient samples via laser‐fabricated electrodes and single‐point calibration. The proposed platform provides rapid and sensitive quantification, with the potential to enable therapeutic drug monitoring and patient stratification according to circulating naxitamab levels, while ...
Andy Bruno, Ruslán Alvarez‐Diduk, Paula Lara, Gabriel Maroli, Cristina Larrosa, Sandra López‐Miralles, Jaume Mora, Carlos J. Rodríguez‐Hernández, Arben Merkoçi   +8 more
wiley   +1 more source

The α-Gal Epitope (Galα1-3Galβ1-4GlcNAc) as Therapeutic Agent in Cancer Immunotherapy, Vaccine Effectiveness Amplification and Injured Tissue Regeneration. [PDF]

Int J Mol Sci
Galili U.
europepmc   +1 more source