Engineering Complexity: Advances in 3D Breast Cancer Models for Precision Oncology
In vitro breast cancer models that closely mimic the complex biological and cellular interactions within the tumor microenvironment hold strong promise for enhancing our understanding of tumor progression, immune system behavior, and resistance to therapies, which are essential for developing personalized cancer treatments. Abstract Engineered in vitro
Wonwoo Jeong, Sang Jin Lee
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Inhibition of the key metabolic pathways, glycolysis and lipogenesis, of oral cancer by bitter melon extract [PDF]
Subhayan Sur +6 more
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Regulatory Mechanisms of LncRNAs in Cancer Glycolysis: Facts and Perspectives
Peng Huang +6 more
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Glycolysis stimulation and storage protein accumulation are hallmarks of maize (Zea mays L.) grain filling [PDF]
Jung‐Tae Kim +9 more
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Fibrillar Bundles as Fibrous Filler Materials for Attaining Cell Anisotropy in Bioprinting
Fibrillar bundles are introduced as a bioprintable additive that enables robust and scalable cellular alignment within 3D constructs through flow‐induced orientation during extrusion. These fibers support strong cell adhesion and polarization across various cell types and significantly enhance myotube alignment in Gelatine‐Methacryloyl (GelMA ...
Sven Heilig +10 more
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Enhanced Glycolysis Supports Cell Survival in EGFR-Mutant Lung Adenocarcinoma by Inhibiting Autophagy-Mediated EGFR Degradation [PDF]
Ji Hye Kim +14 more
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CircRBM33 downregulation inhibits hypoxia-induced glycolysis and promotes apoptosis of breast cancer cells via a microRNA-542-3p/HIF-1α axis [PDF]
Yiming Jiang +5 more
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A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova +5 more
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A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou +10 more
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