Results 71 to 80 of about 260,676 (239)
LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer
Molecular Cancer, 2019 Long noncoding RNAs (lncRNAs) play nonnegligible roles in the epigenetic regulation of cancer cells. This study aimed to identify a specific lncRNA that promotes the colorectal cancer (CRC) progression and could be a potential therapeutic target.
Yun Wang +18 more
semanticscholar +1 more source
International Journal of Molecular Medicine, 2021 Metabolism reprogramming influences the severity of organ dysfunction, progression to fibrosis, and development of disease in acute kidney injury (AKI).
Chuyi Tan +7 more
semanticscholar +1 more source
A new strategy for osteoarthritis therapy: Inhibition of glycolysis
Frontiers in Pharmacology, 2022 Osteoarthritis (OA) is a common degenerative disease of the joints. It is primarily caused by age, obesity, mechanical damage, genetics, and other factors, leading to cartilage degradation, synovial inflammation, and subchondral sclerosis with osteophyte
Chunmei Tan +4 more
doaj +1 more source
Research Progress of Warburg Effect in Hepatocellular Carcinoma
Frontiers in Bioscience-LandmarkThe Warburg effect, also called aerobic glycolysis, refers to tumor cells that metabolize glucose through glycolysis even in the presence of oxygen. This rapid breakdown of glucose fuels the fast development, growth, and migration of tumor cells. Lactate,
Yanguang Yang +8 more
doaj +1 more source
Cell Death and Disease, 2023 Metabolic reprogramming to glycolysis is closely associated with the development of chronic kidney disease (CKD). Although it has been reported that phosphofructokinase 1 (PFK) is a rate-limiting enzyme in glycolysis, the role of the platelet isoform of ...
Shu Yang +7 more
doaj +1 more source
Evolutionary game theory elucidates the role of glycolysis in glioma progression and invasion [PDF]
arXiv, 2008 Tumour progression has been described as a sequence of traits or phenotypes that cells have to acquire if the neoplasm is to become an invasive and malignant cancer. Although the genetic mutations that lead to these phenotypes are random, the process by which some of these mutations become successful and spread is influenced by the tumour ...
arxiv
The role of carbohydrates at the origin of homochirality in biosystems [PDF]
, 2014 Pasteur has demonstrated that the chiral components in a racemic mixture can separate in homochiral crystals. But with a strong chiral discrimination the chiral components in a concentrated mixture can also phase separate into homochiral fluid domains, and the isomerization kinetics can then perform a symmetry breaking into one thermodynamical stable ...
arxiv +1 more source
Molecular Metabolism, 2023 Objective: Cancer cells use glycolysis for generation of metabolic intermediates and ATP needed for cell growth and proliferation. The transcription factor C/EBPβ-LIP stimulates glycolysis and mitochondrial respiration in cancer cells.
Tobias Ackermann +8 more
doaj
Nature Communications, 2020 Evidence suggests that fasting exerts extensive antitumor effects in various cancers, including colorectal cancer (CRC). However, the mechanism behind this response is unclear.
M. Weng +15 more
semanticscholar +1 more source
Quantitative Analysis of the Effective Functional Structure in Yeast Glycolysis [PDF]
arXiv, 2010 Yeast glycolysis is considered the prototype of dissipative biochemical oscillators. In cellular conditions, under sinusoidal source of glucose, the activity of glycolytic enzymes can display either periodic, quasiperiodic or chaotic behavior. In order to quantify the functional connectivity for the glycolytic enzymes in dissipative conditions we ...
arxiv