Results 31 to 40 of about 49,301 (226)
Antibiotics, 2022 Antibiotic treatment strategies for fracture-related infections (FRI) are often extrapolated from periprosthetic joint infections (PJI), although, in contrast to PJI, detailed analysis of pathogens and their antibiotic resistance is missing.
Susanne Baertl +6 more
doaj +1 more source
Biomolecules, 2015 Neutrophil cathepsin G (nCG) is a central serine protease in the human innate immune system, but the importance of its N-glycosylation remains largely undescribed.
Ian Loke +2 more
doaj +1 more source
National Journal of Laboratory Medicine, 2023 Introduction: Staphylococcus aureus (S. aureus) is a ubiquitous pathogen causing various infections in humans. The emergence of drug resistance in S. aureus, especially methicillin resistance, has made treating these infections increasingly tricky, with ...
Thammina Meher Srisai Sudhavani +3 more
doaj +1 more source
Synthesis and In Vitro Characterization of Glycopeptide Drug Candidates Related to PACAP1–23
Molecules, 2021 The search for efficacious treatment of neurodegenerative and progressive neuroinflammatory diseases continues, as current therapies are unable to halt or reverse disease progression.
Christopher R. Apostol +6 more
doaj +1 more source
Antifreeze glycopeptide diastereomers [PDF]
Beilstein Journal of Organic Chemistry, 2012 Antifreeze glycopeptides (AFGPs) are a special class of biological antifreeze agents, which possess the property to inhibit ice growth in the body fluids of arctic and antarctic fish and, thus, enable life under these harsh conditions. AFGPs are composed of 4–55 tripeptide units -Ala-Ala-Thr- glycosylated at the threonine side chains.
Nagel, Lilly +4 more
openaire +3 more sources
Characterization of VRC01, a potent and broadly neutralizing anti-HIV mAb, produced in transiently and stably transformed tobacco [PDF]
, 2014 The proposed clinical trial in Africa of VRC01, a potent broadly neutralizing antibody (bNAb) capable of neutralizing 91% of known HIV-1 isolates, raises concerns about testing a treatment which will be too expensive to be accessible by the most ...
EMEA +4 more
core +1 more source
Parenterally administered vancomycin in 29 dogs and 7 cats (2003‐2017)
Journal of Veterinary Internal Medicine, 2019 Background Vancomycin is commonly used to treat resistant bacterial infections in people. Reported adverse effects of vancomycin in people include acute kidney injury (AKI), neutropenia, and systemic allergic reaction.
Ian M. DeStefano +3 more
doaj +1 more source
Characterization of Cell Glycocalyx with Mass Spectrometry Methods. [PDF]
, 2019 The cell membrane plays an important role in protecting the cell from its extracellular environment. As such, extensive work has been devoted to studying its structure and function.
Lebrilla, Carlito B +3 more
core +2 more sources
Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand [PDF]
, 1992 We have constructed an artificial ligand for the hepatocyte-specific asialoglycoprotein receptor for the purpose of generating a synthetic delivery system for DNA.
Ashwell G. +36 more
core +1 more source
Glycopeptide Antibiotic Resistance Genes in Glycopeptide-Producing Organisms [PDF]
Antimicrobial Agents and Chemotherapy, 1998 ABSTRACT The mechanism of high-level resistance to vancomycin in enterococci consists of the synthesis of peptidoglycan terminating in d -alanyl- d -lactate instead of the usual d -alanyl- d -alanine.
C G, Marshall +3 more
openaire +2 more sources