Results 81 to 90 of about 49,301 (226)

Structure analysis of biologically important prokaryotic glycopolymers [PDF]

, 2013
Of the many post-translational modifications organisms can undertake, glycosylation is the most prevalent and the most diverse. The research in this thesis focuses on the structural characterisation of glycosylation in two classes of glycopolymer (
Ventura, Valeria Victoria, Ventura, Valeria Victoria   +1 more
core   +1 more source

Monosaccharide‐Based Macrocyclic Receptors—History and Recent Applications

Helvetica Chimica Acta, EarlyView.
This perspective provides an overview of most common applications of monosaccharide‐based macrocycles in molecular recognition over the past four decades. The most recent achievements, such as fluorescent ion sensing and selective amino acid binding in aqueous media, including the work from the author's lab, are highlighted. Potential future directions
Bartosz Lewandowski
wiley   +1 more source

Effects of Lycium barbarum polysaccharide on the activation of pathogenic CD4+ T cells in a mouse model of multiple sclerosis

Neural Regeneration Research
Multiple sclerosis is a severe autoimmune disorder that is mainly mediated by pathogenic cluster of CD4+ T cell subsets. Despite advancements in the management of multiple sclerosis, there is a critical need for more effective and safer treatments.
Mengdi Guo, Guozhen Deng, Bin Huang, Zhiyong Lin, Xue Yang, Linglin Dong, Zilin Wang, Yi Guo, Ming Yi, Weiyan Wang, Mei-Ling Jiang, Cun-Jin Zhang   +11 more
doaj   +1 more source

Expression, purification and characterisation of recombinant peptide:N-glycosidase F. : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Biochemistry at Massey University [PDF]

, 2000
PNGase F (Peptide-N4-(N-acetyl-D-glucosaminyl) asparagine amidase F) is an amidohydrolase isolated from the extracellular medium of the Gram-negative bacterium Flavobacterium meningosepticum.
Loo, Trevor Stephen
core  

How shall we use the proteomics toolbox for biomarker discovery? [PDF]

, 2007
Biomarker discovery for clinical purposes is one of the major areas in which proteomics is used. However, despite considerable effort, the successes have been relatively scarce.
Hochstrasser, Denis, Lescuyer, Pierre, Rabilloud, Thierry   +2 more
core   +5 more sources

Matrine Attenuates Neurological Deficits and Neuroinflammation by Inhibiting the HMGB1/RAGE Axis and Ferroptosis in Intracerebral Hemorrhage Mice

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) is a life‐threatening stroke subtype that lacks effective drug therapy. In the context of ICH, neuroinflammation, and ferroptosis are key contributors to secondary brain injury. In this study, we assessed the neuroprotective effects of matrine (MAT) and its mechanism of action involving the HMGB1/RAGE axis in an ...
Pan‐Di Chen, Tao‐Tao Shi, Dan‐Yang Hu, Xiao‐Na Su, Jian‐Xiang Jin, Mao‐Song Chen, Hao Wang, Wei Chen   +7 more
wiley   +1 more source

The Third Dimension of Reading the Sugar Code by Lectins: Design of Glycoclusters with Cyclic Scaffolds as Tools with the Aim to Define Correlations between Spatial Presentation and Activity

Molecules, 2013
Coding of biological information is not confined to nucleic acids and proteins. Endowed with the highest level of structural versatility among biomolecules, the glycan chains of cellular glycoconjugates are well-suited to generate molecular messages ...
Paul V. Murphy, Sabine André, Hans-Joachim Gabius   +2 more
doaj   +1 more source

Glyco‐Nanogels for Modulating Pseudomonas aeruginosa Biofilm

Macromolecular Rapid Communications, EarlyView.
Nanogels presenting α‐galactose and β‐fucose can significantly alter Pseudomonas aeruginosa biofilm dynamics through their interaction with lectins. Application timing is crucial: pre‐treatment reduces biofilm, while treatment after biofilm initiation increases biomass.
Sophia Rosencrantz, Jo Sing Julia Tang, Karina Koenig, Sany Chea, Ruben R. Rosencrantz   +4 more
wiley   +1 more source

Divergent Relationships between Fecal Microbiota and Metabolome following Distinct Antibiotic-Induced Disruptions

mSphere, 2017
The intestinal microbiome plays an essential role in regulating many aspects of host physiology, and its disruption through antibiotic exposure has been implicated in the development of a range of serious pathologies.
Jocelyn M. Choo, Tokuwa Kanno, Nur Masirah Mohd Zain, Lex E. X. Leong, Guy C. J. Abell, Julie E. Keeble, Kenneth D. Bruce, A. James Mason, Geraint B. Rogers   +8 more
doaj   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source