Appropriate Regulation of Antibiotics in Livestock Feed [PDF]
, 2000 For decades, antibiotics have been widely used, saving lives and reducing suffering. Such drugs are routinely employed among both human and farm animal populations.
Goforth, Carol R, Goforth, Robyn L
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A Streamlined Synthesis of Adenosine Vinylsulfonamide Probes for Aminoacyl‐AMP Mimicry in NRPS
ChemBioChem, Volume 27, Issue 7, 14 April 2026.A concise three‐step synthesis enables access to amino acid‐derived adenosine vinylsulfonamide (AVS) probes under mild conditions. Ba(OH)2‐mediated coupling suppresses epimerization, affording stereochemically defined probes that covalently capture nonribosomal peptide synthetase (NRPS) thioesterification states. LC–MS/MS confirms functional engagement
Naoto Haraguchi +6 more
wiley +1 more source
Recent Advances in the Development of Semisynthetic Glycopeptide Antibiotics: 2014-2022. [PDF]
ACS Infect Dis, 2022 van Groesen E, Innocenti P, Martin NI.
europepmc +1 more source
A consensus statement on empiric therapy for suspected gram-positive infections in surgical patients [PDF]
, 2015 15Background: Multidrug resistance among gram-positive pathogens in tertiary and other care centers is common. A systematic decision pathway to help select empiric antibiotic therapy for suspected gram-positive postsurgical infections is presented.
core +1 more source
Breaking Down Barriers: CorA Effectively Targets Staphylococcal Biofilms in Vitro and in Vivo
ChemMedChem, Volume 21, Issue 7, 14 April 2026.Corallopyronin A (CorA), a natural alpha‐pyrone antibiotic, penetrates Staphylococcus aureus biofilms and inhibits RNA polymerase. This work demonstrates CorA's superior efficacy compared to rifampicin and dalbavancin in reducing viable loads in biofilms both in vitro and in vivo. Graphic created in https://BioRender.com.
Stefania De Benedetti +21 more
wiley +1 more source
A42867, a novel glycopeptide antibiotic.
The Journal of Antibiotics, 1989 A42867 is a new glycopeptide antibiotic of the ristocetin-vancomycin class active against aerobic and anaerobic Gram-positive bacteria. A42867 is produced by a strain of Nocardia nov. sp. ATCC 53492. A42867 was isolated during a screening program aimed at the discovery of new members of this glycopeptide class of antibiotics, by affinity chromatography
E. RIVA +10 more
openaire +3 more sources
Taxonomy and chemical characterization of new antibiotics produced by Saccharothrix SA198 isolated from a Saharan soil [PDF]
, 2013 Actinomycete strain SA198, isolated from a Saharan soil sample of Algeria, exhibited antimicrobial activity against Gram-positive and Gram-negative bacteria, and phytopathogenic and toxinogenic fungi.
A. Lebrihi +52 more
core +4 more sources
Synthetic Biology Facilitates Semisynthetic Development of Type V Glycopeptide Antibiotics Targeting Vancomycin-Resistant Enterococcus. [PDF]
J Med Chem, 2023 Koteva K +6 more
europepmc +1 more source
Newest perspectives of glycopeptide antibiotics: biosynthetic cascades, novel derivatives, and new appealing antimicrobial applications. [PDF]
World J Microbiol Biotechnol, 2023 Tian L, Shi S, Zhang X, Han F, Dong H.
europepmc +1 more source
Rapidly Destructive Staphylococcus epidermidis Endocarditis [PDF]
, 2018 : A 29-year-old man with rapidly destructive Staphylococcus epidermidis endocarditis after mitral valve reconstruction is presented. Resistance to rifampin and teicoplanin occurred during antibiotic treatment resulting in clinical failure and valve ...
Berger-Bachi, B. +5 more
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