Results 21 to 30 of about 48,098 (265)

Discovery of Serotransferrin Glycoforms: Novel Markers for Diagnosis of Liver Periductal Fibrosis and Prediction of Cholangiocarcinoma. [PDF]

open access: yes, 2019
Cholangiocarcinoma (CCA) caused by chronic liver fluke infection is a major public health problem in Northeast Thailand. Identification of CCA risk groups is urgently needed for the control of CCA in this region.
Barboza, Mariana   +10 more
core   +2 more sources

Validation and Clinical Application of a New Liquid Chromatography Coupled to Mass Spectrometry (HPLC-MS) Method for Dalbavancin Quantification in Human Plasma

open access: yesSeparations, 2021
Dalbavancin (DBV) is an intravenous long-acting second-generation glycolipopeptide antibiotic with high efficacy and excellent tolerability, approved for use in the treatment of Gram-positive skin and skin structure infections (ABSSSI).
Valeria Avataneo   +13 more
doaj   +1 more source

Tissue Penetration of Antimicrobials in Intensive Care Unit Patients: A Systematic Review—Part I

open access: yesAntibiotics, 2022
The challenging severity of some infections, especially in critically ill patients, makes the diffusion of antimicrobial drugs within tissues one of the cornerstones of chemotherapy.
Stefano Finazzi   +7 more
doaj   +1 more source

Role of therapeutic drug monitoring in pulmonary infections : use and potential for expanded use of dried blood spot samples [PDF]

open access: yes, 2015
Respiratory tract infections are among the most common infections in men. We reviewed literature to document their pharmacological treatments, and the extent to which therapeutic drug monitoring (TDM) is needed during treatment.
Akkerman, Onno W   +6 more
core   +2 more sources

Determination of the safety of glycopeptides lactic acid bacteria in laboratory animals

open access: yesФармакокинетика и Фармакодинамика, 2019
The study of acute toxicity and allergenity glycopeptides lactic acid bacteria in mice and rabbits. At the present level of physical, chemical and biological pollution of the environment, domestic and farm animals in no less, if not more than people ...
O. V. Sofronova   +2 more
doaj   +1 more source

Transient Expression of Tetrameric Recombinant Human Butyrylcholinesterase in Nicotiana benthamiana. [PDF]

open access: yes, 2016
To optimize the expression, extraction and purification of plant-derived tetrameric recombinant human butyrylcholinesterase (prBChE), we describe the development and use of plant viral amplicon-based gene expression system; Tobacco Mosaic Virus (TMV) RNA-
Alkanaimsh, Salem   +13 more
core   +1 more source

Cephalosporin-Glycopeptide Combinations for Use against Clinical Methicillin-Resistant Staphylococcus aureus Isolates: Enhanced In vitro Antibacterial Activity

open access: yesFrontiers in Microbiology, 2017
The empirical combination of both a beta-lactam and glycopeptide to counter potential staphylococcal pathogens may improve the clinical outcomes for cases of Staphylococcus aureus bacteremia.
Hung-Jen Tang   +13 more
doaj   +1 more source

Structure analysis of biologically important prokaryotic glycopolymers [PDF]

open access: yes, 2013
Of the many post-translational modifications organisms can undertake, glycosylation is the most prevalent and the most diverse. The research in this thesis focuses on the structural characterisation of glycosylation in two classes of glycopolymer (
Ventura, Valeria Victoria   +1 more
core   +1 more source

Comparison of Different HILIC Stationary Phases in the Separation of Hemopexin and Immunoglobulin G Glycopeptides and Their Isomers

open access: yesMolecules, 2020
Protein glycosylation analysis is challenging due to the structural variety of complex conjugates. However, chromatographically separating glycans attached to tryptic peptides enables their site-specific characterization.
Katarina Molnarova, Petr Kozlík
doaj   +1 more source

Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes. [PDF]

open access: yes, 2020
The cell surface proteome, the surfaceome, is the interface for engaging the extracellular space in normal and cancer cells. Here we apply quantitative proteomics of N-linked glycoproteins to reveal how a collection of some 700 surface proteins is ...
Coon, Joshua   +5 more
core  

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