Results 51 to 60 of about 26,625 (243)
Advanced Science, EarlyView.SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao +15 more
wiley +1 more source
Glycopeptide Antibiotic Resistance Genes in Glycopeptide-Producing Organisms [PDF]
Antimicrobial Agents and Chemotherapy, 1998 ABSTRACT The mechanism of high-level resistance to vancomycin in enterococci consists of the synthesis of peptidoglycan terminating in d -alanyl- d -lactate instead of the usual d -alanyl- d -alanine.
C G, Marshall +3 more
openaire +2 more sources
Shipin gongye ke-ji, 2023 The aim of this study was to purify angiotensin I-converting enzyme (ACE) inhibitory glycopeptide from quinoa fermented by Mucor wutungkiao and Rhizopus oryzae.
Yuyuan YU +5 more
doaj +1 more source
Selective Enrichment of Glycopeptides Using Aluminum Oxide
, 2013 Protein glycosylation is significantly associated with cells cycle, immune regulation, cells recognition and cells adhesion. Aberrant glycosylation expression is involved in many diseases, such as rheumatoid arthritis, cancer, and chronic obstructive ...
Jiang Wuhui +5 more
core +1 more source
Click maltose as an alternative to reverse phase material for desalting glycopeptides
, 2011 Click maltose as an alternative to reverse phase material for desalting glycopeptidesDesalting peptides before mass spectrometry analysis is important because salts lead to adduct formation, increased chemical noise and ion suppression effect.
Yu, Long +7 more
core +1 more source
Late‐Stage Functionalization of Peptides on the Solid Phase
Angewandte Chemie International Edition, EarlyView.Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner +2 more
wiley +1 more source
Resistance to Glycopeptides in Enterococci [PDF]
Clinical Infectious Diseases, 1997 The development of resistance to glycopeptides (vancomycin and teicoplanin) is one of the best examples of the alternation between success and failure that spans the history of the antibiotic era. The introduction of penicillin G was revolutionary. However, the emergence in the 1950s of clinical isolates of Staphylococcus aureus that were resistant to ...
R, Leclercq, P, Courvalin
openaire +2 more sources
British Journal of Clinical Pharmacology, EarlyView.This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst +8 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.A synthetic methodology has been developed to prepare multifunctional M6P and M6Pn ligands of different valency. The glycopeptides were conjugated to cetuximab and then examined to mediate cellular uptake of fluorescently labeled EGFRvIII. Only cetuximab modified by glycopeptides having 3 or 6 M6P or M6Pn residues demonstrated greater uptake.
Patrycja Lenartowicz +6 more
wiley +1 more source
Enterococcus faecalis an Emerging Microbial Menace in Dentistry-An Insight into the In-Silico Detection of Drug Resistant Genes and Its Protein Diversity [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Antimicrobial drug resistance is evolving as a serious threat to mankind due to indiscriminate use of antibiotics and lack of awareness about the mechanisms involved in drug resistance.
Vijayashree J Priyadharsini +2 more
doaj +1 more source