Results 51 to 60 of about 29,057 (236)
Selective Enrichment of Glycopeptides Using Aluminum Oxide
, 2013 Protein glycosylation is significantly associated with cells cycle, immune regulation, cells recognition and cells adhesion. Aberrant glycosylation expression is involved in many diseases, such as rheumatoid arthritis, cancer, and chronic obstructive ...
Jiang Wuhui +5 more
core +1 more source
Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation
Advanced Science, EarlyView.Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu +8 more
wiley +1 more source
Direct Identification of O-Glycopeptides by Low-Temperature Assisted Nanopore Technique
ResearchO-glycopeptides are highly expressed in various human cancers and play a key role in cancer progression and metastasis, making them promising biomarkers for early diagnostics.
Jia-Hong Wang +6 more
doaj +1 more source
Determination of the safety of glycopeptides lactic acid bacteria in laboratory animals
Фармакокинетика и Фармакодинамика, 2019 The study of acute toxicity and allergenity glycopeptides lactic acid bacteria in mice and rabbits. At the present level of physical, chemical and biological pollution of the environment, domestic and farm animals in no less, if not more than people ...
O. V. Sofronova +2 more
doaj +1 more source
Ferritin as a Nanoparticle Scaffold for Plant‐Produced Next‐Generation Subunit Vaccines
Biotechnology and Bioengineering, EarlyView.ABSTRACT Protein nanoparticles offer an innovative approach to next‐generation subunit vaccine development by displaying antigenic sequences on the nanoparticle surface. Compared to traditional subunit vaccines, protein nanoparticle vaccines often show improved interaction with the immune system due to their particulate size and repetitive epitope ...
Jordan T. VanderBurgt +3 more
wiley +1 more source
Frontiers in Microbiology, 2017 The empirical combination of both a beta-lactam and glycopeptide to counter potential staphylococcal pathogens may improve the clinical outcomes for cases of Staphylococcus aureus bacteremia.
Hung-Jen Tang +13 more
doaj +1 more source
Click maltose as an alternative to reverse phase material for desalting glycopeptides
, 2011 Click maltose as an alternative to reverse phase material for desalting glycopeptidesDesalting peptides before mass spectrometry analysis is important because salts lead to adduct formation, increased chemical noise and ion suppression effect.
Yu, Long +7 more
core +1 more source
Chemistry – A European Journal, EarlyView.Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley +1 more source
Molecules, 2020 Protein glycosylation analysis is challenging due to the structural variety of complex conjugates. However, chromatographically separating glycans attached to tryptic peptides enables their site-specific characterization.
Katarina Molnarova, Petr Kozlík
doaj +1 more source
Stereoselective Synthesis of β‐C‐glycosides From Exoglycals Through Radical C─C Bond Formation
Chemistry – A European Journal, EarlyView.We describe herein a convenient strategy for the preparation of β‐C‐glycosides via the addition of radical species onto exoglycals. This method is efficient, general and achieved in mild conditions starting from xanthates derivatives and using triethylborane as initiator and 4‐tert‐butylcatechol as hydrogen atom source. This hydroalkylation reaction is
Noémie Murard +2 more
wiley +1 more source