Results 71 to 80 of about 29,057 (236)

Les entérocoques résistants aux glycopeptides

, 2010
Enterococcus faecium a développé une multirésistance aux antibiotiques dont les glycopeptides. Les glycopeptides (vancomycine et teicoplanine) agissent sur les entérocoques en se fixant sur les précurseurs de la paroi bactérienne dont ils empêchent ainsi
Vincent Cattoir, Roland Leclercq
core   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

A bivalent glycopeptide to target two putative carbohydrate binding sites on FimH

Beilstein Journal of Organic Chemistry, 2010
FimH is a mannose-specific bacterial lectin found on type 1 fimbriae with a monovalent carbohydrate recognition domain (CRD) that is known from X-ray studies.
Thisbe K. Lindhorst, Kathrin Bruegge, Andreas Fuchs, Oliver Sperling   +3 more
doaj   +1 more source

Tailored for Binding: Alanine‐Modified Poly(1‐Naphthylamine) Targets Serum Albumins

Polymer Engineering &Science, EarlyView.
Alanine modified poly(1‐naphthylamine). ABSTRACT This study presents a new approach for modifying the structural and functional properties of poly(1‐naphthylamine) (PNA) by incorporating the amino acid alanine (Ala) in different molar proportions (80/20, 50/50, and 20/80 for PNA/Ala) through an ultrasound‐assisted polymerization process.
Nuzhat Nabi, Ufana Riaz
wiley   +1 more source

Extended Infusion of Beta-Lactams and Glycopeptides: A New Era in Pediatric Care? A Systematic Review and Meta-Analysis

Antibiotics
Optimizing antibiotic therapy is imperative with rising bacterial resistance and high infection mortality. Extended infusion defined as a continuous infusion (COI) or prolonged infusion (PI) of beta-lactams and glycopeptides might improve efficacy and ...
Andrea Rahel Burch, Lukas von Arx, Barbara Hasse, Vera Neumeier   +3 more
doaj   +1 more source

Synthesis of aromatic glycoconjugates. Building blocks for the construction of combinatorial glycopeptide libraries

Beilstein Journal of Organic Chemistry, 2014
New aromatic glycoconjugate building blocks based on the trifunctional 3-aminomethyl-5-aminobenzoic acid backbone and sugars linked to the backbone by a malonyl moiety were prepared via peptide coupling.
Markus Nörrlinger, Thomas Ziegler
doaj   +1 more source

Reversed-phase depletion coupled with hydrophilic affinity enrichment for the selective isolation of N-linked glycopeptides by using Click OEG-CD matrix

, 2011
Reversed-phase depletion coupled with hydrophilic affinity enrichment for the selective isolation of N-linked glycopeptides by using Click OEG-CD matrixSelective enrichment of glycopeptides is of great importance for protein glycosylation analysis using ...
Zhao, Yanyan, Yu, Long, 李秀玲, Liang, Xinmiao, Li, Xiuling, 梁鑫淼, Guo, Zhimou   +6 more
core   +1 more source

Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy

VIEW, EarlyView.
This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley   +1 more source

In-depth characterization and comparison of the N-glycosylated proteome of two-dimensional- and three-dimensional-cultured breast cancer cells and xenografted tumors.

PLoS ONE, 2020
Native intact N-glycopeptide analysis can provide access to the comprehensive characteristics of N-glycan occupancy, including N-glycosites, N-glycan compositions, and N-glycoproteins for complex samples.
Yonghong Mao, Yang Zhao, Yong Zhang, Hao Yang   +3 more
doaj   +1 more source

Snake Gut Microbiota as a Source of Anti‐Inflammatory Probiotics: Isolation and Functional Characterization of Two Novel Strains

Integrative Zoology, EarlyView.
This study assessed the probiotic potential of intestinal microbiomes from five snake species using metagenomics and in vitro isolation, identifying two promising strains (Lactobacillus johnsonii DA0116 and Limosilactobacillus reuteri DA0218) through comprehensive screening.
Xuena Kang, Lan Hu, Jiarong Song, Zhenjie Zhang, Yi Li, Qingqing Zhang, Cuiling Luo, Yu Pang, Peng Guo, Bisong Yue, Ping Li, Zhenxin Fan   +11 more
wiley   +1 more source