Results 81 to 90 of about 29,057 (236)

Telavancin — New Antimicrobial Active Against Multiresistant Gram-Positive Pathogens. Clinical and Microbiological Features in Questions and Answers [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2015
Telavancin is a first marketed representative of semisinthetic lipoglycopeptides — new generation of glycopeptide antimicrobials. Telavancin is registered for the treatment of nosocomial pneumonia and skin and soft tissue infections caused by Gram ...
Dekhnich A.V., Zubareva N.A., Kozlov R.S., Popov D.A., Romanov A.V., Rudnov V.A.   +5 more
doaj  

Determinants of Immunoglobulin‐G N‐Glycan Patterns in the Aging General Population

Allergy, EarlyView.
The effect of demographic and lifestyle factors on IgG N‐glycosylation, which determines IgG's inflammatory response, remains poorly characterized. Aging, higher BMI, female sex, smoking, and heavy alcohol consumption are determinants of IgG N‐glycome patterns, which are indicative of inflammation. Women exhibit a distinct change in IgG N‐glycosylation
Samantha Leonard, Ralph Heijmans, Virgil A. S. H. Dalm, Silvan Licher, Jan Nouta, Steinar Gijze, David Falck, P. Martin van Hagen, Robin Peeters, Manfred Wuhrer, Layal Chaker   +10 more
wiley   +1 more source

A simple integrated system for rapid analysis of sialic-acid-containing N-glycopeptides from human serum

, 2013
Terminal sialylation is very important in cancer biology and has been extensively investigated for the discovery of potential clinical biomarkers of cancers.
Wang, Fangjun, Sun, Deguang, Zou, Hanfa, 邹汉法, Zhu, Jun, Dong, Jing, Ye, Mingliang, Chen, Rui, Wang, Liming, Cheng, Kai   +9 more
core   +1 more source

A posttranslational proteomic survey of a single anatomically preserved human 20‐week postconception brain

Journal of Anatomy, EarlyView.
A well‐preserved 20 post‐conception week human brain was obtained and finely dissected into 18 anatomically distinct regions, including the pia mater. Each region underwent in‐depth proteomic analysis, encompassing both total protein content and post‐translational modifications.
S. Bandiera, H. Bogetofte, P. Jensen, R. Hussain, S. A. Nischal, L. Rihova, G. J. Clowry, M. R. Larsen, Z. Molnár, B. C. Carlyle   +9 more
wiley   +1 more source

Urban ants as potential mechanical vectors of pathogenic and antibiotic‐resistant bacteria in a Brazilian hospital

Medical and Veterinary Entomology, EarlyView.
Nine ant taxa were identified in a Brazilian hospital, with Tapinoma melanocephalum and Dorymyrmex brunneus being the most abundant. Eighty‐five percent of collected ants yielded detectable bacterial growth, including clinically relevant genera such as Acinetobacter, Pseudomonas, Escherichia coli and Pluralibacter.
Luana Biggi Souza, Anny Karoliny de Lima Dionisio, Mayara Acioli Cedrim, Luiz Carlos Silva Dias Neto, Ellymaira Freitas Pontes, Yáskara Veruska Ribeiro Barros, Renato Júnior Cavalcante da Silva, Ênio Jose Bassi, Jacques Hubert Charles Delabie, Ana Lucia Biggi Souza, Leticia Anderson   +10 more
wiley   +1 more source

Deep Learning Enables Identification of Antimicrobial Peptides Through Mechanochromic Fingerprints

Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.
We demonstrate a new platform for antimicrobial peptide identification by combining polydiacetylene, hyperspectral imaging, and deep learning. The trained model classifies distinct spectral fingerprints into 14 peptide classes with 96.79% accuracy, revealing previously hidden molecular information beyond conventional colorimetric sensing.
Jiali Chen, Che‐Lun Chin, Qingzhen Zhu, Ling Chao, Kaori Sugihara   +4 more
wiley   +2 more sources

Serum Biomarker Discovery by Quantification of Glycoproteins with Dimethyl Labeling of Non-glycopeptides

, 2010
A robust, reproducible and high-throughput method was developed for the quantitative analysis of concentration changes of glycoproteins in human serum.
叶明亮, 邹汉法, 陈锐
core  

Capture and Dimethyl Labeling of Glycopeptides on Hydrazide Beads for Quantitative Glycoproteomics Analysis

, 2012
Incorporation of isotopic tag onto peptides via chemical labeling is a popular approach for quantitative proteomics. Chemical labeling via solution based methods usually lead to a tedious process and sample loss because several sample preparation steps ...
Qin, Hongqiang, Wang, Fangjun, Zou, Hanfa, 邹汉法, Ye, Mingliang, Sun, Zhen, Cheng, Kai, Dong, Mingming   +7 more
core   +1 more source

Jacalin interacts with Asn-linked glycopeptides containing multi-antennary oligosaccharide structure with terminal α-linked galactose [PDF]

, 1998
The carbohydrate binding properties of jacalin lectin were examined using RAF9 cell-derived d-[6-3H]glucosamine-radiolabeled total glycopeptides containing N-linked and O-linked oligosaccharides.
Su-Il Do, Su Il Do, Lee, Ki-Young, Do, Su-Il, Ki-Young Lee   +4 more
core   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

Transfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike, Albert Bondt, Douwe Schulte, Rien Leuvenink, Dirk Jan Mons, Peter C. Ligthart, E. Joanne T. Verweij, AFRICARhE Consortium, Enrico Lopriore, E. J. T. Joanne Verweij, Tienke Vermeiden, Thomas van den Akker, C. Ellen van der Schoot, Derek P. de Winter, Renske van Oever, Abera Kenay Tura, Tadesse Gure, Assefa Desalew, Tewodros Tesfa, Konjit Eshetu, Jeremia Pyuza, Rafiki N. Mjema, Priscus John Mapendo, Jeremiah John Hhera, Bariki Mchome, Patricia Swai, Blandina T. Mmbaga, Aisa Shayo, Peter Moons, Kondwani Kawaza, Luis Gadama, Albert J. R. Heck, C. Ellen van der Schoot, Gestur Vidarsson   +33 more
wiley   +1 more source