Results 101 to 110 of about 29,057 (236)
Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential
Angewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber +4 more
wiley +1 more source
Molecules, 2019 The initial contact of pathogens with host cells is usually mediated by their adhesion to glycan structures present on the cell surface in order to enable infection. Furthermore, glycans play important roles in the modulation of the host immune responses
Sandra Behren, Ulrika Westerlind
doaj +1 more source
Allergenicity of α‐Gal‐Containing Products
Allergy, EarlyView.
Frederik Bloch Mangaard +4 more
wiley +1 more source
Synthesis of Glycopeptide Antibiotic Peptide Substrates Using Knorr‐Pyrazole Chemistry
ChemMedChem, Volume 21, Issue 17, 14 September 2026.The glycopeptide antibiotics (GPAs) are important clinical antibiotics. While chemoenzymatic synthesis of more hydrophilic GPAs like vancomycin has aided our understanding of GPA crosslinking, hydrophobic GPAs remain underexplored. Here, we show that modified Knorr‐pyrazole chemistry improves access to hydrophobic peptidyl‐CoAs, with such substrates ...
Jemma Gullick +4 more
wiley +1 more source
Old and New Glycopeptide Antibiotics: Action and Resistance
Antibiotics, 2014 Glycopeptides are considered antibiotics of last resort for the treatment of life-threatening infections caused by relevant Gram-positive human pathogens, such as Staphylococcus aureus, Enterococcus spp. and Clostridium difficile.
Elisa Binda +2 more
doaj +1 more source
, 2011 Selective Enrichment of N-linked Glycopeptides Using Hydrophilic Interaction Chromatography-based ...
于龙 +5 more
core
CNS Active O-Linked Glycopeptides that Penetrate the BBB
, 2015 Naturally occurring glycopeptides and glycoproteins play important roles in biological processes. Glycosylation is one of the most common post-translational modifications in vivo.
Robin ePolt +3 more
core +1 more source
Selective Enrichment of N-linked Glycopeptides Using Titanium Dioxide under Uniform Condition
, 2011 Selective Enrichment of N-linked Glycopeptides Using Titanium Dioxide under Uniform ...
李秀玲 +3 more
core
Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders
Advanced Science, Volume 13, Issue 50, 7 September 2026.Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley +1 more source
Cancer Medicine, Volume 15, Issue 9, September 2026.ABSTRACT Purpose This study aimed to evaluate the association between ramelteon use and mortality outcomes in patients with sepsis and cancer. The research question was whether ramelteon use is associated with reduced mortality in this high‐risk patient population. Methods A retrospective analysis of the MIMIC‐IV database was conducted.
Chendong Wang, Mingjie Liu, Jia Song
wiley +1 more source