Results 111 to 120 of about 29,057 (236)

In Silico and In Vitro Evaluation of Atriplex halimus: Antibacterial Activity, Molecular Docking, ADMET Profiling, and Cytotoxicity Assessment

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Atriplex halimus aqueous and hydroethanolic extracts, rich in trans‐cinnamic acid, catechin, epigallocatechin, and vitamin C. The Extracts showed modest antibacterial activity against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa, and dose‐dependent cytotoxicity in Artemia salina.
Mohammed Roubi   +10 more
wiley   +1 more source

Layer-by-layer assembly of multilayer polysaccharide coated magnetic nanoparticles for the selective enrichment of glycopeptides

open access: yes, 2013
Magnetic nanoparticles (MNPs) coated with multilayer polysaccharide shells have been fabricated using a layer-by-layer approach via the alternate deposition of hyaluronan (HA) and chitosan (CS) onto the surface, and the hydrophilic materials were ...
Qin, Hongqiang   +10 more
core   +1 more source

Paeonol Alleviate Cisplatin‐ and Noise‐Induced Hearing Loss by Preserving Hair Cell Ribosome Biogenesis

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Paeonol protects against cisplatin‐ and noise‐induced hearing loss by mitigating oxidative damage and preserving protein homeostasis in cochlear hair cells, revealing a novel mechanism involving ribosome biogenesis. ABSTRACT Background Hearing loss primarily results from irreversible cochlear hair cell (HC) damage caused by factors such as noise, aging,
Minhui Xia   +8 more
wiley   +1 more source

IgG Glycosylation Patterns May Identify Distinct Clinical Trajectories in Fibromyalgia Patients: A Longitudinal Pilot Study

open access: yesEuropean Journal of Pain, Volume 30, Issue 8, September 2026.
ABSTRACT Background Altered immunoglobulin G (IgG) glycosylation was implicated in various conditions, but its role in fibromyalgia (FM) remains unclear. This study investigated IgG glycosylation patterns in FM patients and associations between glycosylation changes and clinical profiles.
Ling‐Cheng Kung   +4 more
wiley   +1 more source

MS analysis of sialylation of GalNAcosylated synthetic HR glycopeptides (sHR) by ST6GalNAcI.

open access: yes, 2014
(A) Acceptor sHR glycopeptides for ST6GalNAcI with 3 to 7 GalNAc residues were generated by recombinant GalNAc-T2 after a 15-min reaction. (B) sHR glycopeptides produced after over-night reaction with ST6GalNAcI.
Jan Novak (156878)   +11 more
core   +1 more source

Results From a Phase 2, Open‐Label Study Evaluating the Safety, Tolerability, and Effect on Ataxia of GLM101 in Three Adult Patients With PMM2‐CDG

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
ABSTRACT Phosphomannomutase 2 congenital disorder of glycosylation (PMM2‐CDG) is a rare, autosomal recessive disease caused by PMM2 deficiency, which impairs conversion of mannose‐6‐phosphate into mannose‐1‐phosphate (M1P) and disrupts N‐linked glycosylation.
Mercedes Serrano   +3 more
wiley   +1 more source

glycopeptides

open access: yes, 2014
Citation: 'glycopeptides' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.G02656 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
openaire   +1 more source

Galectin‐4: A Novel Mediator of Human Intervertebral Disc Degeneration

open access: yesJOR SPINE, Volume 9, Issue 3, September 2026.
Galectin‐4 correlates with intervertebral disc degeneration, independent of age, sex, or underlying pathology. Functionally, it activates NF‐κB signaling and induces pro‐inflammatory and matrix‐degrading responses, with stronger effects in nucleus pulposus cells, identifying it as a novel molecular player in disc degeneration.
Christine Strauss   +12 more
wiley   +1 more source

Surviving the Nucleus Pulposus Desert: Next‐Generation Strategies for Intervertebral Disc Cell Therapy

open access: yesJOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACTBackgroundLow back pain remains the leading cause of disability worldwide, with intervertebral disc degeneration representing a major biological contributor. Although cell‐based therapies have shown promise in preclinical models, clinical translation has yielded modest and inconsistent outcomes.
Tynhinane Hamidouche   +9 more
wiley   +1 more source

Large-scale characterization of intact N-glycopeptides using an automated glycoproteomic method

open access: yes, 2014
The detailed characterization of site-specific glycosylation requires the identification of glycan composition and specific attachment sites on proteins, which need the identification of intact glycopeptides by mass spectrometry.
DanielFigeys   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy