Glyco-biomarkers: Potential determinants of cellular physiology and pathology [PDF]
Once dismissed as just the icing on the cake, sugar molecules are emerging as vital components in life’s intricate machinery. Our understanding of their function within the context of the proteins and lipids to which they are attached has matured rapidly,
Alavi, A, Axford, JS
core +2 more sources
Selection of binding targets in parasites using phage-display and aptamer libraries in vivo and in vitro [PDF]
Parasite infections are largely dependent on interactions between pathogen and different host cell populations to guarantee a successful infectious process.
Alves, Maria Julia Manso +2 more
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Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion [PDF]
The most lethal form of malaria in humans is caused by Plasmodium falciparum. These parasites invade erythrocytes, a complex process involving multiple ligand-receptor interactions.
Cowman, Alan +12 more
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Identification of lectin counter-receptors on cell membranes by proximity labelling [PDF]
Lectin-glycan interactions play important roles in many biological systems, but the nature of glycoprotein counter-receptors expressed on cell membranes is often poorly understood.
Crocker, Paul R. +2 more
core +2 more sources
Sphingomyelinase D Activity in Sicarius tropicus Venom : Toxic Potential and Clues to the Evolution of SMases D in the Sicariidae Family [PDF]
The spider family Sicariidae includes three genera, Hexophthalma, Sicarius and Loxosceles. The three genera share a common characteristic in their venoms: the presence of Sphingomyelinases D (SMase D).
Bertani, Rogerio +4 more
core +1 more source
Population genomic analysis reveals a rich speciation and demographic history of orang-utans (Pongo pygmaeus and Pongo abelii) [PDF]
To gain insights into evolutionary forces that have shaped the history of Bornean and Sumatran populations of orang-utans, we compare patterns of variation across more than 11 million single nucleotide polymorphisms found by previous mitochondrial and ...
Bustamante, Carlos D. +10 more
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Biological functions of blood group antigens [PDF]
Os antígenos de grupos sanguíneos eritrocitários são estruturas macromoleculares localizadas na superfície extracelular da membrana eritrocitária. Com o desenvolvimento de estudos moleculares, mais de 250 antígenos são conhecidos e estão organizados em ...
BONIFÁCIO, Silvia L. +1 more
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Структурні та кількісні зміни вуглеводних детермінант глікопротеїнів еритроцитарних мембран при введенні агматину за умов експериментального цукрового діабету [PDF]
Встановлено, що розвиток експериментального цукрового діабету супроводжується посиленням процесу десіалювання олігосахаридних детермінант еритроцитарних глікопротеїнів, зменшенням кількості N- та О-зв’язаних гліканів у їхньому складі, а також зниженням ...
Бродяк, І.В. +3 more
core +1 more source
The influence of host genetics on erythrocytes and malaria infection: is there therapeutic potential? [PDF]
As parasites, Plasmodium species depend upon their host for survival. During the blood stage of their life-cycle parasites invade and reside within erythrocytes, commandeering host proteins and resources towards their own ends, and dramatically ...
Burgio, Gaetan +3 more
core +4 more sources
Glycomics-based analysis of chicken red blood cells provides insight into the selectivity of the viral agglutination assay [PDF]
Agglutination of red blood cells (RBCs), including chicken RBCs (cRBCs), has been used extensively to estimate viral titer, to screen glycan-receptor binding preference, and to assess the protective response of vaccines.
Amano +34 more
core +1 more source

