Results 51 to 60 of about 1,770 (162)
Blood group O expression in normal tissues and tumors
The FEBS Journal, Volume 292, Issue 21, Page 5697-5722, November 2025.The H antigen (O blood group), the precursor to A and B blood groups, is expressed on human erythrocytes. However, reliable reagents for H antigen detection are lacking. We generated two novel monoclonal antibodies using sea lamprey immunization, Tn4‐31L and OmcFL3‐02, that specifically detect the H antigen on glycan microarrays, glycoproteins, and ...
Ea Kristine Clarisse Tulin +11 more
wiley +1 more source
Severe hereditary spherocytosis and distal renal tubular acidosis associated with the total absence of band 3 [PDF]
, 2000 Absence of band 3, associated with the mutation Coimbra (V488M) in the homozygous state, caused severe hereditary spherocytosis in a young child. Although prenatal testing was made available to the parents, it was declined.
Alliosio, N +11 more
core
Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility
Advanced Therapeutics, Volume 8, Issue 10, October 2025.This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam +5 more
wiley +1 more source
Transfusion, Volume 65, Issue 10, Page 1922-1934, October 2025.Abstract Background Although blood group variation was first described over a century ago, our understanding of the genetic variation affecting antigenic expression on the red blood cell surface in many populations is lacking. This deficit limits the ability to accurately type patients, especially as serological testing is not available for all ...
Paige E. Haffener +7 more
wiley +1 more source
Beyond FimH: Diversity and Relevance of Carbohydrate‐Binding Fimbrial Proteins in Escherichia coli
ChemBioChem, Volume 26, Issue 17, September 15, 2025.This review discusses fimbrial lectins found in Escherichia coli (E. coli) other than FimH, which could be targeted to treat E. coli pathogenicity as an alternative to antibiotic treatment. Escherichia coli (E. coli) is responsible for multiple diseases in humans and animals.
Oliwier R. Dulawa +3 more
wiley +1 more source
Modelling pathogen load dynamics to elucidate mechanistic determinants of host-Plasmodium falciparum interactions [PDF]
, 2019 During infection, increasing pathogen load stimulates both protective and harmful aspects of the host response. The dynamics of this interaction are hard to quantify in humans, but doing so could improve understanding of mechanisms of disease and ...
Bretscher, Michael +16 more
core +4 more sources
Thoracic Cancer, Volume 16, Issue 17, September 2025.A 47‐year‐old woman was diagnosed with invasive thymoma 13 years ago. She had undergone repeated surgeries, as well as chemotherapy and radiation therapy. Chemotherapy was discontinued after the patient developed normocytic anemia. Bone marrow biopsy results revealed pure red cell aplasia (PRCA).
Kento Kono +8 more
wiley +1 more source
Large‐Scale Chemoenzymatic Synthesis of a Glycophorin A Tetrasaccharide Motif and Its Analogues
Asian Journal of Organic Chemistry, Volume 14, Issue 8, August 2025.A large‐scale chemoenzymatic method was developed to synthesize natural and modified analogues of the Glycophorin A tetrasaccharide with either C9 or C5 terminal α‐2,3‐sialic acid variants. Selective α‐2,6‐sialylation of galactosamine was achieved by maintaining acetylation of the galactose during the course of enzymatic reactions. The products can aid
Ivan A. Gagarinov +5 more
wiley +1 more source
Structural and Functional Studies of Carbohydrates. [PDF]
, 1991 Plasmodium falciparum is the parasite responsible for a major loss of human life due to malaria. The biochemistry of invasion of the parasite into human red cells is the subject of much study and controversy.
Dhume, Shirish Trymbak
core +2 more sources
Drug Testing and Analysis, Volume 17, Issue 8, Page 1417-1442, August 2025.Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis +2 more
wiley +1 more source