Results 201 to 210 of about 955,216 (365)

Predicted antiviral potential of phytochemicals prolific in Cleistanthus bracteosus Jabl. and essential oils of Artemisia scoparia and Thuja orientalis against Nipah virus and Human metapneumovirus: An AI-driven in-silico study. [PDF]

PLoS One
Dassanayake MK, Khoo TJ, Chong CH, Ansari MT, Di Martino P, Zanchi FB, Figiel A, Szumny A, Elfar OA, Wiart C, Symonds R.   +10 more
europepmc   +1 more source

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

Immuno-Proteomic Features Associated to Relapse Risk in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. [PDF]

Neurol Neuroimmunol Neuroinflamm
Gallaccio G, Müller A, Wang M, Diekmann LM, Otto C, Dinoto A, Chiodega V, Schwake C, Jarius S, Usnich T, Sperber PS, Anderhalten L, Ongphichetmetha T, Byars A, Subasic D, Kunkel D, Ayzenberg I, Mariotto S, Samadzadeh S, Paul F, Böttcher C.   +20 more
europepmc   +1 more source

Phenylsulfonylfuroxans as Modulators of Multidrug-Resistance-Associated Protein-1 and P-Glycoprotein

, 2010
Roberta Fruttero, Marco Crosetti, Konstantin Chegaev, Stefano Guglielmo, Alberto Gasco, Francesco Berardi, Mauro Niso, Roberto Perrone, Maria Antonietta Panaro, Nicola Antonio Colabufo   +9 more
openalex   +2 more sources

Targeting GALNT7 Disrupts the TAZ O‐GalNAcylation Feedback Loop to Suppress Gallbladder Cancer Progression

Advanced Science, EarlyView.
Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu, Ming Zhang, Yunxiang Feng, Yibo Deng, Kai Zhao, Xiangyu Li, Yun Lu, Li Tian, Tao Yang, Wei Yao, Jianming Wang, Zhengdong Deng   +11 more
wiley   +1 more source

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

Advanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen, Xiongfeng He, Zihao Li, Zidong Chen, Jiajin Sun, Xinyu Jiang, Yunhui Zhang, Lizhang Wu, Ran Wang, Jingnan Lu, Bo Wang, Kezhou Cai, Baocai Xu   +12 more
wiley   +1 more source

Structures of New World mammarenavirus glycoproteins as targets for antibody-mediated neutralization. [PDF]

J Virol
Taylor LJ, Helguera G, Maruyama J, Rodriguez JA.   +3 more
europepmc   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

Correction: Assessment of clinically relevant drugs as feline P-glycoprotein substrates. [PDF]

Front Vet Sci
Mealey KL, Burke NS.
europepmc   +1 more source

Antimetastatic effect of glycoprotein isolated from rice bran on colon 26-M3.1 cell line

, 2017
Ho‐Young Park, Taek Joon Yoon, Wookyung Lee, Yoonsook Kim, Hee‐Don Choi   +4 more
openalex   +2 more sources