Results 1 to 10 of about 693,614 (188)
New Neutralizing Epitope Exposed on the Domain II of Tick-Borne Encephalitis Virus Envelope Glycoprotein E [PDF]
Viruses, 2023 Orthoflavivirus encephalitidis, formerly tick-borne encephalitis virus (TBEV), belongs to the Orthoflavivirus genus. TBEV is transmitted by tick bites and infection with TBEV can lead to serious disorders of the central nervous system.
Andrey Matveev +7 more
doaj +2 more sources
Alphaherpesvirus glycoprotein E: A review of its interactions with other proteins of the virus and its application in vaccinology [PDF]
Frontiers in Microbiology, 2022 The viral envelope glycoprotein E (gE) is required for cell-to-cell transmission, anterograde and retrograde neurotransmission, and immune evasion of alphaherpesviruses.
Yaru Ning +51 more
doaj +2 more sources
Adjuvanted Recombinant Glycoprotein E Herpes Zoster Vaccine. [PDF]
Clin Infect Dis, 2020 Abstract The adjuvanted recombinant glycoprotein E herpes zoster (HZ) vaccine is superior to the live attenuated HZ vaccine, with an efficacy >90% against HZ in healthy immunocompetent adults aged ≥50 years after vaccination. In pivotal studies, the efficacy of the new vaccine varied very little with the age of the vaccinee and ...
Levin MJ, Weinberg A.
europepmc +4 more sources
Immunogenicity of varicella zoster virus glycoprotein E DNA vaccine. [PDF]
Exp Ther Med, 2016 In the present study a eukaryotic expression vector of varicella zoster virus (VZV) glycoprotein E (gE) was constructed and enabled to express in COS7 cells. Furthermore, a specific immune response against the VZV gE eukaryotic expression plasmid was induced in BALB/c mice.
Bao L +6 more
europepmc +4 more sources
Glycoprotein In Vitro N-Glycan Processing Using Enzymes Expressed in E. coli
Molecules, 2023 Protein N-glycosylation is a common post-translational modification that plays significant roles on the structure, property, and function of glycoproteins.
Libo Zhang +7 more
doaj +5 more sources
Preclinical immunogenicity of an adenovirus-vectored vaccine for herpes zoster
Human Vaccines & Immunotherapeutics, 2023 Herpes zoster (HZ) results from waning immunity following childhood infection with varicella zoster virus (VZV) but is preventable by vaccination with recombinant HZ vaccine or live HZ vaccine (two doses or one dose, respectively).
Marta Ulaszewska +3 more
doaj +1 more source
Conformational Changes of the Flavivirus E Glycoprotein [PDF]
Structure, 2004 Dengue virus, a member of the Flaviviridae family, has a surface composed of 180 copies each of the envelope (E) glycoprotein and the membrane (M) protein. The crystal structure of an N-terminal fragment of E has been determined and compared with a previously described structure.
Zhang, Ying +7 more
openaire +3 more sources
Elastic modulus and toughness of orb spider glycoprotein glue. [PDF]
PLoS ONE, 2018 An orb web's prey capture thread features tiny glue droplets, each formed of an adhesive glycoprotein core surrounded by an aqueous layer. Small molecules in the aqueous layer confer droplet hygroscopicity and maintain glycoprotein viscoelasticity ...
Brent D Opell +2 more
doaj +1 more source
Genome sequence of canine herpesvirus [PDF]
, 2016 Canine herpesvirus is a widespread alphaherpesvirus that causes a fatal haemorrhagic disease of neonatal puppies. We have used high-throughput methods to determine the genome sequences of three viral strains (0194, V777 and V1154) isolated in the United ...
Davison, Andrew +5 more
core +14 more sources
Human Vaccines & Immunotherapeutics, 2020 A vaccine to prevent genital herpes is an unmet public health need. We previously reported that a trivalent vaccine containing herpes simplex virus type 2 (HSV-2) glycoproteins C, D, and E (gC2, gD2, gE2) produced in baculovirus and administered with CpG/
Kevin Egan +4 more
doaj +1 more source