Results 261 to 270 of about 693,713 (287)

Antiviral agents targeting glycans on dengue virus E-glycoprotein

Expert Review of Anti-infective Therapy, 2011
The molecular recognition of dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN) with arthropod-derived N-glycans on E-glycoprotein is essential for dengue virus (DENV) infection in humans. Therefore, the specific interaction of DC-SIGN with N-glycans on E-glycoprotein is a promising target for development of virus ...
Kazuya I P J, Hidari, Takashi, Suzuki
openaire   +2 more sources

A Chimeric Antibody to Varicella-Zoster Virus Glycoprotein E

Hybridoma, 2005
Varicella-Zoster virus (VZV) immune globulin (VZIG) derived from pooled human serum is currently used in immunotherapy of VZV-associated complications of chickenpox and shingles. We developed a mouse-human chimeric antibody against a VZV glycoprotein E (gE) epitope as a safer replacement for VZIG.
Vidya, Shankar, John J, Kools, Kathryn L, Armour, Mike R, Clark   +3 more
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Epitopes on glycoprotein E and on the glycoprotein E/glycoprotein I complex of bovine herpesvirus 1 are expressed by all of 222 isolates and 11 vaccine strains

Archives of Virology, 2000
Glycoprotein E (gE) of bovine herpesvirus 1 (BHV1) forms a complex with glycoprotein I (gI) and plays an important role in cell-to-cell spread mechanisms of the virus, but is not essential for propagation of the virus. To study the antigenic variability of BHV1 glycoprotein E, a set of six well characterised monoclonal antibodies (MAbs) was established
Rijsewijk, Frans, Kaashoek, Marianne, Langeveld, Jan Pm, Maris-Veldhuis, Mieke, Magdalena, Juana, Verschuren, S. B E, Meloen, Rob, Van Oirschot, Jan   +7 more
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Epitope-specific antibody response against glycoprotein E of pseudorabies virus

Clinical Diagnostic Laboratory Immunology, 1994
In this study we investigated the epitope-specific antibody response against glycoprotein E (gE) of pseudorabies virus. Epitope-specific antibody responses were investigated by enzyme-linked immunoperoxidase monolayer assays. In a vaccinated crossbred pig population, most pigs responded to antigenic domain E and to a lesser degree to antigenic domains ...
L, Jacobs, T G, Kimman
openaire   +2 more sources

Immunological characterisation of the rubella E 1 glycoprotein

Archives of Virology, 1986
Three epitopes have been identified on rubella virion envelope polypeptide E 1 using monoclonal antibodies. Antibodies to two of the epitopes, E 1EP1 and E 1EP2, show both haemagglutination inhibition and neutralization activities whereas antibodies to the remaining epitope, E 1EP3, show neutralizing activity only.
Linda Ho-Terry, G. M. Terry, A. Cohen, P. Londesborough   +3 more
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Epitope mapping of dengue 1 virus E glycoprotein using monoclonal antibodies

Archives of Virology, 1995
Ten monoclonal antibodies (MAbs) were raised against dengue 1 (DEN 1, Hawaii) virus E glycoprotein. Specificity of the MAbs was tested by ELISA and immunofluorescence. Eight were DEN 1 type-specific, one was DEN group-reactive (DGR) and one was flavivirus cross-reactive (FCR).
E, Simantini, K, Banerjee
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Biosynthesis and interaction of glycoproteins E and I of canine herpesvirus

Virus Research, 1999
In cells infected with canine herpesvirus (CHV), the mature form of glycoprotein E (gE) had a molecular weight of 94 kDa, and that of glycoprotein I (gI) had a broad range of molecular weights of 55-62 kDa. gE and gI formed a complex like gE and gI of other alphaherpesviruses.
Y, Nishikawa, X, Xuan, H, Otsuka
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Platelet activation by dimeric β2‐glycoprotein I requires signaling via both glycoprotein Ibα and apolipoprotein E receptor 2′

Journal of Thrombosis and Haemostasis, 2008
Dimerization of beta(2)-glycoprotein I (beta(2)-GPI) by autoantibodies is thought to trigger the clinical manifestations observed in the antiphospholipid syndrome. Arterial thrombosis, a frequently occurring clinical manifestation of the antiphospholipid syndrome, is a process in which platelets play a crucial role. Previous work has shown that binding
R T, Urbanus, M T T, Pennings, R H W M, Derksen, P G, de Groot   +3 more
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Meningoencephalitis in Mice Infected with an Equine Herpesvirus 1 Strain KyA Recombinant Expressing Glycoprotein I and Glycoprotein E

Virus Genes, 2004
One of the consequences of equine herpesvirus 1 (EHV-1) infection in the natural host is a neurological disease that can lead to paralysis. The pathology associated with EHV-1-induced neurological disease includes vasculitis of the small blood vessels within the central nervous system and subsequent damage to the surrounding neural tissue.
Arthur R, Frampton, Patrick M, Smith, Yunfei, Zhang, Warren D, Grafton, Tomio, Matsumura, Nikolaus, Osterrieder, Dennis J, O'Callaghan   +6 more
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Construction and Vaccine Studies on a Pseudorabies Virus with Deletions in Glycoprotein I and Glycoprotein E Genes

Advanced Materials Research, 2011
A pseudorabies virus (PRV) mutant with deletions in genes for glycoprotein I (gI) and glycoprotein E (gE) was constructed and evaluated as a candidate vaccine strain for its protective by virulent wildtype (wt) PRV Ea strain challenge in pigs. Transfer plasmid pIESE was constructed and co-transfected with PRV genome into IBRS-2 cells to generate a ...
Song Lin Zhang, Mei Lin Jin, Huan Chun Chen   +2 more
openaire   +1 more source