Results 21 to 30 of about 693,713 (287)

Consequences of cell-to-cell P-glycoprotein transfer on acquired multidrug resistance in breast cancer: a cell population dynamics model [PDF]

open access: yes, 2010
Cancer is a proliferation disease affecting a genetically unstable cell population, in which molecular alterations can be somatically inherited by genetic, epigenetic or extragenetic transmission processes, leading to a cooperation of neoplastic cells ...
Boulangé-Lecomte, Céline   +4 more
core   +6 more sources

A trivalent subunit antigen glycoprotein vaccine as immunotherapy for genital herpes in the guinea pig genital infection model

open access: yesHuman Vaccines & Immunotherapeutics, 2017
An estimated 417 million people worldwide ages 15 to 49 are infected with herpes simplex virus type 2 (HSV-2), the most common cause of genital ulcer disease.
Sita Awasthi   +3 more
doaj   +1 more source

The effect of differences in the third domain of the glycoprotein E of tick-borne encephalitis virus of the Far Eastern, Siberian and European subtypes on the binding of recombinant D3 proteins with a chimeric antibody

open access: yesВавиловский журнал генетики и селекции, 2019
Currently, a therapeutic drug based on recombinant antibodies for the prevention and treatment of tick-borne encephalitis virus (TBEV) is developed in ICBFM SB RAS, and the chimeric antibody ch14D5 is considered as one of the key components of this drug.
I. K. Baykov   +5 more
doaj   +1 more source

Optimisation of the enzyme-linked lectin assay for enhanced glycoprotein and glycoconjugate analysis [PDF]

open access: yes, 2011
Lectin’s are proteins capable of recognising and binding to specific oligosaccharide tructures found on glycoproteins and other biomoloecules. As such they have found tility for glycoanalytical applications.
Afrough   +48 more
core   +2 more sources

Structural and Functional Aspects of Ebola Virus Proteins

open access: yesPathogens, 2021
Ebola virus (EBOV), member of genus Ebolavirus, family Filoviridae, have a non-segmented, single-stranded RNA that contains seven genes: (a) nucleoprotein (NP), (b) viral protein 35 (VP35), (c) VP40, (d) glycoprotein (GP), (e) VP30, (f) VP24, and (g) RNA
Sahil Jain   +4 more
doaj   +1 more source

Protective effect of the whole plant extract of Evolvulus alsinoides on glycoprotein alterations in streptozotocin induced diabetic rats

open access: yesJournal of Acute Disease, 2013
Objective: To assess the effect of Evolvulus alsinoides (E. alsinoides) on glycoprotein levels in liver, kidney and pancreas of control and diabetes induced rats. Methods: Wistar albino rats were used for the present study.
Gomathi Duraisamy   +4 more
doaj   +1 more source

Allelic and genotypic frequencies of platelet glycoprotein polymorphisms in a Portuguese population

open access: yesRevista Portuguesa de Cardiologia, 2013
Introduction and objectives: We studied genotypic and allelic frequencies of polymorphisms that can affect platelet function, namely the Kozak, VNTR and HPA-2 polymorphisms of glycoprotein Ibα, the PlA polymorphism of glycoprotein IIIa and the C807T ...
Luís Bernardo Pina-Cabral   +11 more
doaj   +1 more source

The influence of 5-HT(2C) and MDR1 genetic polymorphisms on antipsychotic-induced weight gain in female schizophrenic patients [PDF]

open access: yes, 2008
We investigated the relationships between functional genetic variants of the 5-HT(2C) receptor and multidrug-resistant protein (MDR1), coding for P-glycoprotein, and second generation antipsychotic (SDA)-induced weight gain among 108 female schizophrenic
Bilušić, Hrvoje   +5 more
core   +1 more source

Functional Divergence of Glycoprotein Hormone Receptors [PDF]

open access: yes, 2010
Two lamprey glycroprotein hormone receptors (lGpH-R I and II) highly similar with gnathostome GpH-Rs were cloned from sea lamprey testes and thyroid, respectively.
Freamat, Mihael, Sower, Stacia A.
core   +3 more sources

Herpes Simplex Virus Type 1 Glycoprotein E Is Required for Axonal Localization of Capsid, Tegument, and Membrane Glycoproteins [PDF]

open access: yesJournal of Virology, 2005
ABSTRACTHerpes simplex virus type 1 (HSV-1) glycoprotein E (gE) promotes cell-to-cell spread at basolateral surfaces of epithelial cells, but its activity in neurons is less clear. We used the mouse retina infection model and neuronal cell cultures to define the spread phenotype of gE mutant viruses.
Fushan, Wang   +5 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy