Results 151 to 160 of about 124,462 (290)
Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]
, 2008 Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama +4 more
core +1 more source
Novel Ligands for Platelet Glycoprotein VI [PDF]
Thrombosis and Haemostasis, 2018 openaire +2 more sources
3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence
Advanced Healthcare Materials, EarlyView.Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes +11 more
wiley +1 more source
Advanced ScienceInhibiting the platelet glycoprotein VI (GPVI) receptor is a promising strategy for reducing cerebral ischemia‐reperfusion injury (CIRI) without severe compromise of hemostasis, while targeting glycoprotein IIb/IIIa (integrin αIIbβ3) causes bleeding. The
Xiaoyan Chen +11 more
doaj +1 more source
Modulation of Glycoprotein VI and Its Downstream Signaling Pathways as an Antiplatelet Target. [PDF]
Int J Mol Sci, 2022 Fuentes E.
europepmc +1 more source
Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives
Advanced Materials, EarlyView.Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi +4 more
wiley +1 more source
Targeting GPVI as a novel antithrombotic strategy
Journal of Blood Medicine, 2014 Robert K Andrews, Jane F Arthur, Elizabeth E Gardiner Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia Abstract: While platelet activation is essential to maintain blood vessel patency and minimize loss of blood upon ...
Andrews RK, Arthur JF, Gardiner EE
doaj
Advanced Materials, EarlyView.This work introduces an injectable mesoporous silica rod scaffold that confines lentiviral vectors to the injection site, enabling localized dendritic cell recruitment and transduction. The platform sustains antigen expression, promotes robust T‐cell activation, and enhances antitumor immunity.
Thanh Loc Nguyen +12 more
wiley +1 more source
Platelet Activation by Antisense Oligonucleotides (ASOs) in the Göttingen Minipig, including an Evaluation of Glycoprotein VI (GPVI) and Platelet Factor 4 (PF4) Ontogeny. [PDF]
Pharmaceutics, 2023 Valenzuela A +6 more
europepmc +1 more source
AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing
Advanced Materials, EarlyView.This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee +21 more
wiley +1 more source