Results 1 to 10 of about 353,399 (368)

Production of Recombinant Replication-defective Lentiviruses Bearing the SARS-CoV or SARS-CoV-2 Attachment Spike Glycoprotein and Their Application in Receptor Tropism and Neutralisation Assays

Bio-Protocol, 2021
For enveloped viruses, such as SARS-CoV-2, transmission relies on the binding of viral glycoproteins to cellular receptors. Conventionally, this process is recapitulated in the lab by infection of cells with isolated live virus. However, such studies can
Nazia Thakur, Giulia Gallo, Ahmed Elreafey, Dalan Bailey   +3 more
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Efficient cellular and humoral immune response and production of virus-neutralizing antibodies by the Hepatitis B Virus S/preS116-42 antigen

Frontiers in Immunology, 2022
Despite the availability of improved antiviral therapies, infection with Hepatitis B virus (HBV) remains a3 significant health issue, as a curable treatment is yet to be discovered.
Ana-Maria Pantazica, Mihaela-Olivia Dobrica, Catalin Lazar, Cristina Scurtu, Catalin Tucureanu, Iuliana Caras, Irina Ionescu, Adriana Costache, Adrian Onu, Jihong Liu Clarke, Crina Stavaru, Norica Branza-Nichita   +11 more
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Challenges and Prospects of Plant-Derived Oral Vaccines against Hepatitis B and C Viruses

Plants, 2021
Hepatitis B and C viruses chronically affect approximately 3.5% of the global population, causing more than 800,000 deaths yearly due to severe liver pathogenesis.
Ana-Maria Madalina Pantazica, Lia-Maria Cucos, Crina Stavaru, Jihong-Liu Clarke, Norica Branza-Nichita   +4 more
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Probing the Hepatitis B Virus E-Antigen with a Nanopore Sensor Based on Collisional Events Analysis

Biosensors, 2022
Real-time monitoring, simple operation, and cheaper methods for detecting immunological proteins hold the potential for a solid influence on proteomics and human biology, as they can promote the onset of timely diagnoses and adequate treatment protocols.
Ioana C. Bucataru, Isabela Dragomir, Alina Asandei, Ana-Maria Pantazica, Alina Ghionescu, Norica Branza-Nichita, Yoonkyung Park, Tudor Luchian   +7 more
doaj   +1 more source

Recent Advances in Lectin-Based Affinity Sorbents for Protein Glycosylation Studies

Frontiers in Molecular Biosciences, 2021
Glycosylation is one of the most significant post-translational modifications occurring to proteins, since it affects some of their basic properties, such as their half-life or biological activity. The developments in analytical methodologies has greatly
Anastasia Goumenou, Nathalie Delaunay, Valérie Pichon, Valérie Pichon   +3 more
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Targeted O-glycoproteomics for the development of diagnostic markers for advanced colorectal cancer

Frontiers in Oncology, 2023
Aberrant glycosylation is a prominent feature of cancer, that can be used as targets to improve the existing cancer biomarkers, and help to assess metastasis risks, and therapeutic effects.
Daisuke Takakura, Shoko Ohashi, Noritoshi Kobayashi, Motohiko Tokuhisa, Yasushi Ichikawa, Nana Kawasaki   +5 more
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Triglyceride-Rich Lipoproteins and Glycoprotein A and B Assessed by 1H-NMR in Metabolic-Associated Fatty Liver Disease

Frontiers in Endocrinology, 2022
High plasma triglyceride (TG) levels and chronic inflammation are important factors related to metabolic-associated fatty liver disease in patients at cardiovascular risk. Using nuclear magnetic resonance (1H-NMR), we aimed to study the triglyceride-rich
Juan Moreno-Vedia, Juan Moreno-Vedia, Roser Rosales, Roser Rosales, Roser Rosales, Enrique Ozcariz, Dídac Llop, Dídac Llop, Maribel Lahuerta, María Benavent, Ricardo Rodríguez-Calvo, Ricardo Rodríguez-Calvo, Ricardo Rodríguez-Calvo, Núria Plana, Núria Plana, Núria Plana, Angels Pedragosa, Lluís Masana, Lluís Masana, Lluís Masana, Antoni Castro, Antoni Castro, Daiana Ibarretxe, Daiana Ibarretxe, Daiana Ibarretxe, Josefa Girona, Josefa Girona, Josefa Girona   +27 more
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Glycoproteins From Rabdosia japonica var. glaucocalyx Regulate Macrophage Polarization and Alleviate Lipopolysaccharide-Induced Acute Lung Injury in Mice via TLR4/NF-κB Pathway

Frontiers in Pharmacology, 2021
Background and Aims:Rabdosia japonica var. glaucocalyx is a traditional Chinese medicine (TCM) for various inflammatory diseases. This present work aimed to investigate the protective effects of R. japonica var.
An-qi Ren, Hui-jun Wang, Hai-yan Zhu, Guan Ye, Kun Li, Dao-feng Chen, Tao Zeng, Hong Li   +7 more
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Single-dose of a replication-competent adenovirus-vectored vaccine provides sterilizing protection against Rift Valley fever virus challenge

Frontiers in Immunology, 2022
Rift Valley fever virus (RVFV) is one of the most important virulent pathogens causing severe disease in animals and humans. However, there is currently no approved vaccine to prevent RVFV infection in humans. The use of human adenovirus serotype 4 (Ad4)
Ting Bian, Busen Wang, Guangcheng Fu, Meng Hao, Yi Chen, Ting Fang, Shuling Liu, Changming Yu, Jianmin Li, Jianmin Li, Wei Chen   +10 more
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Heat Stress of Algal Partner Hinders Colonization Success and Alters the Algal Cell Surface Glycome in a Cnidarian-Algal Symbiosis

Microbiology Spectrum, 2022
Corals owe their ecological success to their symbiotic relationship with dinoflagellate algae (family Symbiodiniaceae). While the negative effects of heat stress on this symbiosis are well studied, how heat stress affects the onset of symbiosis and ...
Shumpei Maruyama, Paige E. Mandelare-Ruiz, Mark McCauley, Wenjing Peng, Byeong Gwan Cho, Junyao Wang, Yehia Mechref, Sandra Loesgen, Virginia M. Weis   +8 more
doaj   +1 more source