Results 1 to 10 of about 463,259 (348)

Production of Recombinant Replication-defective Lentiviruses Bearing the SARS-CoV or SARS-CoV-2 Attachment Spike Glycoprotein and Their Application in Receptor Tropism and Neutralisation Assays

Bio-Protocol, 2021
For enveloped viruses, such as SARS-CoV-2, transmission relies on the binding of viral glycoproteins to cellular receptors. Conventionally, this process is recapitulated in the lab by infection of cells with isolated live virus. However, such studies can
Nazia Thakur, Giulia Gallo, Ahmed Elreafey, Dalan Bailey   +3 more
doaj   +1 more source

Efficient cellular and humoral immune response and production of virus-neutralizing antibodies by the Hepatitis B Virus S/preS116-42 antigen

Frontiers in Immunology, 2022
Despite the availability of improved antiviral therapies, infection with Hepatitis B virus (HBV) remains a3 significant health issue, as a curable treatment is yet to be discovered.
Ana-Maria Pantazica, Mihaela-Olivia Dobrica, Catalin Lazar, Cristina Scurtu, Catalin Tucureanu, Iuliana Caras, Irina Ionescu, Adriana Costache, Adrian Onu, Jihong Liu Clarke, Crina Stavaru, Norica Branza-Nichita   +11 more
doaj   +1 more source

Challenges and Prospects of Plant-Derived Oral Vaccines against Hepatitis B and C Viruses

Plants, 2021
Hepatitis B and C viruses chronically affect approximately 3.5% of the global population, causing more than 800,000 deaths yearly due to severe liver pathogenesis.
Ana-Maria Madalina Pantazica, Lia-Maria Cucos, Crina Stavaru, Jihong-Liu Clarke, Norica Branza-Nichita   +4 more
doaj   +1 more source

Probing the Hepatitis B Virus E-Antigen with a Nanopore Sensor Based on Collisional Events Analysis

Biosensors, 2022
Real-time monitoring, simple operation, and cheaper methods for detecting immunological proteins hold the potential for a solid influence on proteomics and human biology, as they can promote the onset of timely diagnoses and adequate treatment protocols.
Ioana C. Bucataru, Isabela Dragomir, Alina Asandei, Ana-Maria Pantazica, Alina Ghionescu, Norica Branza-Nichita, Yoonkyung Park, Tudor Luchian   +7 more
doaj   +1 more source

Targeted O-glycoproteomics for the development of diagnostic markers for advanced colorectal cancer

Frontiers in Oncology, 2023
Aberrant glycosylation is a prominent feature of cancer, that can be used as targets to improve the existing cancer biomarkers, and help to assess metastasis risks, and therapeutic effects.
Daisuke Takakura, Shoko Ohashi, Noritoshi Kobayashi, Motohiko Tokuhisa, Yasushi Ichikawa, Nana Kawasaki   +5 more
doaj   +1 more source

Potential Alphavirus Inhibitors From Phytocompounds – Molecular Docking and Dynamics Based Approach

Innovative Biosystems and Bioengineering, 2023
Background. Alphaviral diseases are an economic burden all over the world due to their chronicity and distribution worldwide. The glycoproteins E1 and E2 are important for binding to the surface of the host cell by interacting with the receptors and non ...
Maneesha Sharma, Anu Bansal, Shikha Suman, Neeta Raj Sharma   +3 more
doaj   +1 more source

The Expression of Hemagglutinin by a Recombinant Newcastle Disease Virus Causes Structural Changes and Alters Innate Immune Sensing

Vaccines, 2021
Recombinant Newcastle disease viruses (rNDV) have been used as bivalent vectors for vaccination against multiple economically important avian pathogens. NDV-vectored vaccines expressing the immunogenic H5 hemagglutinin (rNDV-H5) are considered attractive
Fiona Ingrao, Victoria Duchatel, Isabel Fernandez Rodil, Mieke Steensels, Eveline Verleysen, Jan Mast, Bénédicte Lambrecht   +6 more
doaj   +1 more source

Quantitative changes of main components of erythrocyte membranes which define architectonics of cells under pttg gene knockout [PDF]

The Ukrainian Biochemical Journal, 2014
A pttg gene knockout affects the functional state of erythron in mice which could be associated with structural changes in the structure of erythrocyte membranes.
О. P. Kanyuka, Ye. Z. Filyak, O. R. Kulachkovskyy, Y. L. Osyp, N. O. Sybirna   +4 more
doaj   +1 more source

Triglyceride-Rich Lipoproteins and Glycoprotein A and B Assessed by 1H-NMR in Metabolic-Associated Fatty Liver Disease

Frontiers in Endocrinology, 2022
High plasma triglyceride (TG) levels and chronic inflammation are important factors related to metabolic-associated fatty liver disease in patients at cardiovascular risk. Using nuclear magnetic resonance (1H-NMR), we aimed to study the triglyceride-rich
Juan Moreno-Vedia, Juan Moreno-Vedia, Roser Rosales, Roser Rosales, Roser Rosales, Enrique Ozcariz, Dídac Llop, Dídac Llop, Maribel Lahuerta, María Benavent, Ricardo Rodríguez-Calvo, Ricardo Rodríguez-Calvo, Ricardo Rodríguez-Calvo, Núria Plana, Núria Plana, Núria Plana, Angels Pedragosa, Lluís Masana, Lluís Masana, Lluís Masana, Antoni Castro, Antoni Castro, Daiana Ibarretxe, Daiana Ibarretxe, Daiana Ibarretxe, Josefa Girona, Josefa Girona, Josefa Girona   +27 more
doaj   +1 more source

Carbohydrate composition of rat intestine surface mucus layer after ceftriaxone treatment [PDF]

The Ukrainian Biochemical Journal, 2016
The epidemiological studies have shown that antibiotic treatment increases the susceptibility to inflammatory bowel disease development. The disturbance of mucus layer integrity might be one of the possible mechanisms. The aim of the present study was to
Yu. V. Holota, Ya. A. Olefir, T. V. Dovbynchuk, G. M. Tolstanova   +3 more
doaj   +1 more source