Results 1 to 10 of about 244,382 (297)

Hans Paulsen: Contributions to the Investigations of Glycoprotein Biosynthesis [PDF]

Molecules
Hans Paulsen was one of the first scientists who believed that chemistry should be applied to biology and medicine. His interest in natural products and their roles solidified in the 1970s. He passed on his knowledge to hundreds of students and coworkers
Inka Brockhausen
doaj   +2 more sources

Production of Recombinant Replication-defective Lentiviruses Bearing the SARS-CoV or SARS-CoV-2 Attachment Spike Glycoprotein and Their Application in Receptor Tropism and Neutralisation Assays

Bio-Protocol, 2021
For enveloped viruses, such as SARS-CoV-2, transmission relies on the binding of viral glycoproteins to cellular receptors. Conventionally, this process is recapitulated in the lab by infection of cells with isolated live virus. However, such studies can
Nazia Thakur, Giulia Gallo, Ahmed Elreafey, Dalan Bailey   +3 more
doaj   +1 more source

Efficient cellular and humoral immune response and production of virus-neutralizing antibodies by the Hepatitis B Virus S/preS116-42 antigen

Frontiers in Immunology, 2022
Despite the availability of improved antiviral therapies, infection with Hepatitis B virus (HBV) remains a3 significant health issue, as a curable treatment is yet to be discovered.
Ana-Maria Pantazica, Mihaela-Olivia Dobrica, Catalin Lazar, Cristina Scurtu, Catalin Tucureanu, Iuliana Caras, Irina Ionescu, Adriana Costache, Adrian Onu, Jihong Liu Clarke, Crina Stavaru, Norica Branza-Nichita   +11 more
doaj   +1 more source

Challenges and Prospects of Plant-Derived Oral Vaccines against Hepatitis B and C Viruses

Plants, 2021
Hepatitis B and C viruses chronically affect approximately 3.5% of the global population, causing more than 800,000 deaths yearly due to severe liver pathogenesis.
Ana-Maria Madalina Pantazica, Lia-Maria Cucos, Crina Stavaru, Jihong-Liu Clarke, Norica Branza-Nichita   +4 more
doaj   +1 more source

Probing the Hepatitis B Virus E-Antigen with a Nanopore Sensor Based on Collisional Events Analysis

Biosensors, 2022
Real-time monitoring, simple operation, and cheaper methods for detecting immunological proteins hold the potential for a solid influence on proteomics and human biology, as they can promote the onset of timely diagnoses and adequate treatment protocols.
Ioana C. Bucataru, Isabela Dragomir, Alina Asandei, Ana-Maria Pantazica, Alina Ghionescu, Norica Branza-Nichita, Yoonkyung Park, Tudor Luchian   +7 more
doaj   +1 more source

Targeted O-glycoproteomics for the development of diagnostic markers for advanced colorectal cancer

Frontiers in Oncology, 2023
Aberrant glycosylation is a prominent feature of cancer, that can be used as targets to improve the existing cancer biomarkers, and help to assess metastasis risks, and therapeutic effects.
Daisuke Takakura, Shoko Ohashi, Noritoshi Kobayashi, Motohiko Tokuhisa, Yasushi Ichikawa, Nana Kawasaki   +5 more
doaj   +1 more source

The Expression of Hemagglutinin by a Recombinant Newcastle Disease Virus Causes Structural Changes and Alters Innate Immune Sensing

Vaccines, 2021
Recombinant Newcastle disease viruses (rNDV) have been used as bivalent vectors for vaccination against multiple economically important avian pathogens. NDV-vectored vaccines expressing the immunogenic H5 hemagglutinin (rNDV-H5) are considered attractive
Fiona Ingrao, Victoria Duchatel, Isabel Fernandez Rodil, Mieke Steensels, Eveline Verleysen, Jan Mast, Bénédicte Lambrecht   +6 more
doaj   +1 more source

Triglyceride-Rich Lipoproteins and Glycoprotein A and B Assessed by 1H-NMR in Metabolic-Associated Fatty Liver Disease

Frontiers in Endocrinology, 2022
High plasma triglyceride (TG) levels and chronic inflammation are important factors related to metabolic-associated fatty liver disease in patients at cardiovascular risk. Using nuclear magnetic resonance (1H-NMR), we aimed to study the triglyceride-rich
Juan Moreno-Vedia, Juan Moreno-Vedia, Roser Rosales, Roser Rosales, Roser Rosales, Enrique Ozcariz, Dídac Llop, Dídac Llop, Maribel Lahuerta, María Benavent, Ricardo Rodríguez-Calvo, Ricardo Rodríguez-Calvo, Ricardo Rodríguez-Calvo, Núria Plana, Núria Plana, Núria Plana, Angels Pedragosa, Lluís Masana, Lluís Masana, Lluís Masana, Antoni Castro, Antoni Castro, Daiana Ibarretxe, Daiana Ibarretxe, Daiana Ibarretxe, Josefa Girona, Josefa Girona, Josefa Girona   +27 more
doaj   +1 more source

Mutations in a set of ancient matrisomal glycoprotein genes across neoplasia predispose to disruption of morphogenetic transduction

Computational and Systems Oncology, 2022
Misexpression and remodeling of the extracellular matrix is a canonical hallmark of cancer, although the extent of cancer‐associated aberrations in the genes coding for extracellular matrix (ECM) proteins and the consequences thereof are not well ...
Jimpi Langthasa, Satyarthi Mishra, Monica U, Ronak Kalal, Ramray Bhat   +4 more
doaj   +1 more source

Well Put Together—A Guide to Accessorizing with the Herpesvirus gH/gL Complexes

Viruses, 2022
Herpesviruses are enveloped, double-stranded DNA viruses that infect a variety of hosts across the animal kingdom. Nine of these establish lifelong infections in humans, for which there are no cures and few vaccine or treatment options.
Gonzalo L. Gonzalez-Del Pino, Ekaterina E. Heldwein   +1 more
doaj   +1 more source