Evaluation of Clinical Efficacy of Intravenous Glyco-P® (Glycopyrrolate)
Background: Glycopyrrolate has been widely used globally as an adjunct in anesthesia since early 1970’s. However, this agent has never been used in Thailand until recent introduction of the Glyco-P® (0.2 mg IV glycopyrrolate).
Prasert Sawasdiwipachai
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Glycopyrrolate does not influence the visual or motor induced increase in regional cerebral perfusion [PDF]
Acetylcholine may contribute to the increase in regional cerebral blood flow (rCBF) during cerebral activation since glycopyrrolate, a potent inhibitor of acetylcholine, abolishes the exercise-induced increase in middle cerebral artery mean flow velocity.
Kim Zillo Rokamp +7 more
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Evaluation of Glycopyrrolate as an Anticholinergic in Buffalo Calves (Bubalus bubalis)
Twelve experimental trials were undertaken on clinically healthy male buffalo calves. Glycopyrrolate was injected @ 0.01 mg/kg, IM. After glycopyrrolate administration, two animals became ataxic.
S. Singh +4 more
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Dose selection for glycopyrrolate/eFlow® phase III clinical studies: results from GOLDEN (Glycopyrrolate for Obstructive Lung Disease via Electronic Nebulizer) phase II dose-finding studies [PDF]
Background Long-acting muscarinic antagonists (LAMAs) are recommended for the treatment of chronic obstructive pulmonary disease (COPD). Glycopyrrolate/eFlow® is an investigational drug–device combination of the LAMA glycopyrrolate administered by an ...
James F. Donohue +3 more
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Iontophoretic and Microneedle Mediated Transdermal Delivery of Glycopyrrolate
Purpose: The objective of this study was to investigate the use of iontophoresis, soluble microneedles and their combination for the transdermal delivery of glycopyrrolate.
Meera Gujjar, Ajay K. Banga
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Compounded glycopyrrolate is a compelling choice for drooling children: five years of facility experience [PDF]
Background Describe the efficacy of a galenic glycopyrrolate formulation and its impact on patients with sialorrhea Quality of Life (QoL), including costs analysis.
Davide Zanon +6 more
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Inhaled glycopyrrolate for the treatment of chronic obstructive pulmonary disease
Donald P Tashkin,1 Nicholas J Gross2 1Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 2Department of Medicine, University Medical Research LLC, Saint Francis Hospital and Medical Center, Hartford, CT, USA Abstract:
Tashkin DP, Gross NJ
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Craig LaForce,1 Gregory Feldman,2 Selwyn Spangenthal,3 Joerg H Eckert,4 Michelle Henley,5 Francesco Patalano,4 Peter D’Andrea5 1North Carolina Clinical Research, Raleigh, NC, USA; 2South Carolina Pharmaceutical Research, Spartanburg, SC, USA ...
LaForce C +6 more
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A case report: Glycopyrrolate for treatment of exercise-induced hyperhidrosis
Objective: Hyperhidrosis can cause dehydration and exercise intolerance. There are several case reports of extremely high sweat rates in athletes. We present as case report of a 17-year-old male with the highest sweat rate recorded in the literature (5.8
Matthew Negaard +6 more
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Role of nebulized glycopyrrolate in the treatment of chronic obstructive pulmonary disease [PDF]
Pierachille Santus,1 Dejan Radovanovic,1 Andrea Cristiano,1 Vincenzo Valenti,2 Maurizio Rizzi1 1Department of Biomedical and Clinical Sciences (DIBIC), University of Milan, Division of Respiratory Diseases, “L.
Santus P +4 more
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