Results 11 to 20 of about 8,639 (159)

Evaluation of Clinical Efficacy of Intravenous Glyco-P® (Glycopyrrolate)

open access: yesSiriraj Medical Journal, 2017
Background: Glycopyrrolate has been widely used globally as an adjunct in anesthesia since early 1970’s. However, this agent has never been used in Thailand until recent introduction of the Glyco-P® (0.2 mg IV glycopyrrolate).
Prasert Sawasdiwipachai
doaj   +4 more sources

Glycopyrrolate does not influence the visual or motor induced increase in regional cerebral perfusion [PDF]

open access: yesFrontiers in Physiology, 2014
Acetylcholine may contribute to the increase in regional cerebral blood flow (rCBF) during cerebral activation since glycopyrrolate, a potent inhibitor of acetylcholine, abolishes the exercise-induced increase in middle cerebral artery mean flow velocity.
Kim Zillo Rokamp   +7 more
doaj   +2 more sources

Evaluation of Glycopyrrolate as an Anticholinergic in Buffalo Calves (Bubalus bubalis)

open access: yesItalian Journal of Animal Science, 2010
Twelve experimental trials were undertaken on clinically healthy male buffalo calves. Glycopyrrolate was injected @ 0.01 mg/kg, IM. After glycopyrrolate administration, two animals became ataxic.
S. Singh   +4 more
doaj   +2 more sources

Dose selection for glycopyrrolate/eFlow® phase III clinical studies: results from GOLDEN (Glycopyrrolate for Obstructive Lung Disease via Electronic Nebulizer) phase II dose-finding studies [PDF]

open access: yesRespiratory Research, 2017
Background Long-acting muscarinic antagonists (LAMAs) are recommended for the treatment of chronic obstructive pulmonary disease (COPD). Glycopyrrolate/eFlow® is an investigational drug–device combination of the LAMA glycopyrrolate administered by an ...
James F. Donohue   +3 more
doaj   +2 more sources

Iontophoretic and Microneedle Mediated Transdermal Delivery of Glycopyrrolate

open access: yesPharmaceutics, 2014
Purpose: The objective of this study was to investigate the use of iontophoresis, soluble microneedles and their combination for the transdermal delivery of glycopyrrolate.
Meera Gujjar, Ajay K. Banga
doaj   +2 more sources

Compounded glycopyrrolate is a compelling choice for drooling children: five years of facility experience [PDF]

open access: yesItalian Journal of Pediatrics, 2021
Background Describe the efficacy of a galenic glycopyrrolate formulation and its impact on patients with sialorrhea Quality of Life (QoL), including costs analysis.
Davide Zanon   +6 more
doaj   +2 more sources

Inhaled glycopyrrolate for the treatment of chronic obstructive pulmonary disease

open access: yesInternational Journal of COPD, 2018
Donald P Tashkin,1 Nicholas J Gross2 1Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 2Department of Medicine, University Medical Research LLC, Saint Francis Hospital and Medical Center, Hartford, CT, USA Abstract:
Tashkin DP, Gross NJ
doaj   +1 more source

Efficacy and safety of twice-daily glycopyrrolate in patients with stable, symptomatic COPD with moderate-to-severe airflow limitation: the GEM1 study

open access: yesInternational Journal of COPD, 2016
Craig LaForce,1 Gregory Feldman,2 Selwyn Spangenthal,3 Joerg H Eckert,4 Michelle Henley,5 Francesco Patalano,4 Peter D’Andrea5 1North Carolina Clinical Research, Raleigh, NC, USA; 2South Carolina Pharmaceutical Research, Spartanburg, SC, USA ...
LaForce C   +6 more
doaj   +1 more source

A case report: Glycopyrrolate for treatment of exercise-induced hyperhidrosis

open access: yesSAGE Open Medical Case Reports, 2017
Objective: Hyperhidrosis can cause dehydration and exercise intolerance. There are several case reports of extremely high sweat rates in athletes. We present as case report of a 17-year-old male with the highest sweat rate recorded in the literature (5.8
Matthew Negaard   +6 more
doaj   +3 more sources

Role of nebulized glycopyrrolate in the treatment of chronic obstructive pulmonary disease [PDF]

open access: yesDrug Design, Development and Therapy, 2017
Pierachille Santus,1 Dejan Radovanovic,1 Andrea Cristiano,1 Vincenzo Valenti,2 Maurizio Rizzi1 1Department of Biomedical and Clinical Sciences (DIBIC), University of Milan, Division of Respiratory Diseases, “L.
Santus P   +4 more
doaj   +2 more sources

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