Results 21 to 30 of about 8,639 (159)

Oral glycopyrrolate for the treatment of chronic severe drooling caused by neurological disorders in children

Neuropsychiatric Disease and Treatment, 2011
Marian L EvattDepartment of Neurology, Atlanta Veterans Administration Hospital and Emory University School of Medicine, Atlanta, GA, USAAbstract: Excessive drooling may complicate the care of children with chronic neurological conditions by socially ...
Evatt ML
doaj   +2 more sources

Long-Term Stability of Glycopyrrolate Oral Solution Galenic Compound at Different Storage Conditions [PDF]

Pharmaceutics
Glycopyrrolate is a competitive muscarinic receptor antagonist used in the treatment of sialorrhea, especially in pediatrics. Degradation research was conducted to better understand the stability of the active pharmaceutical ingredient (API).
Barbara Bellich, Martina Franzin, Debora Curci, Mario Cirino, Alessandra Maestro, Giada Bennati, Gabriele Stocco, Gianpiero Adami, Natalia Maximova, Domenico Leonardo Grasso, Egidio Barbi, Davide Zanon   +11 more
doaj   +2 more sources

Evaluation of efficacy and safety of glycopyrrolate - xylazine - propofol anesthesia in buffalo calves [PDF]

Veterinary World, 2015
Aim: To evaluate the efficacy and safety of glycopyrrolate - xylazine - propofol anesthesia in buffalo calves. Materials and Methods: The study was conducted on six clinically healthy male buffalo calves, 6-12 months of age, and weighing between 130 and
Sandeep Potliya, Ashok Kumar, Sandeep Kumar, Sukhbir Singh , Sarvan Kumar   +4 more
doaj   +2 more sources

Glycopyrrolate in toxic exposure to ammonia gas

Journal of Emergencies, Trauma and Shock, 2011
Ammonia (NH 3 ) is a highly water-soluble, colorless, irritant gas with a unique pungent odor. Liquid ammonia stored under high pressure is still widely used for refrigeration in cold stores used for storing grains.
Bhalla A, Mahi S, Sharma N, Singh S
doaj   +2 more sources

Updates in COPD Management: From Inflammatory Pathways to Targeted Therapies. [PDF]

Eur J Clin Invest
COPD is a heterogeneous disease driven by overlapping neutrophilic and eosinophilic inflammatory pathways. This review highlights the shift from symptom‐based treatment toward phenotype‐ and biomarker‐directed care. Blood eosinophils, FeNO, and IgE predict corticosteroid responsiveness and identify candidates for biologic therapy.
Raman S, Rahman S, Polverino F, Adrish M.   +3 more
europepmc   +2 more sources

Pharmacokinetics of Intramuscular and Intravenous Glycopyrrolate in Juvenile New Zealand White Rabbits. [PDF]

J Vet Pharmacol Ther
ABSTRACT Glycopyrrolate is an alternative to atropine to treat bradyarrhythmias in anesthetized rabbits; however, there are no pharmacokinetic studies in the literature. Six female New Zealand White rabbits received glycopyrrolate 0.05 mg/kg intravenously (IV) in the cephalic vein or intramuscularly (IM) in a complete crossover design.
Marchiori J, Sanchez A, Messenger K, Reinhart JM, Beaufrère H, Fonfara S, Valverde A, Gu Y, Johnson R.   +8 more
europepmc   +2 more sources

Don't Sweat It: Cannabinoid CB1 Receptors Reduce Sweating in a Mouse Model. [PDF]

FASEB J
A new galvanic skin response‐based approach offers a simple method for measuring sweating in the paws of mice. This method is used to demonstrate that cannabinoid CB1 receptors reduce baseline sweating in mice, likely via inhibition of sympathetic acetylcholine release via axonal CB1 receptors.
Murataeva N, Youkilis J, Rao Y, Straiker A.   +3 more
europepmc   +2 more sources

Sugammadex reversal of muscle relaxant blockade provided less Post-Anesthesia Care Unit adverse effects than neostigmine/glycopyrrolate

Journal of the Formosan Medical Association, 2022
Sugammadex is a direct reversal agent of aminosteroid muscle relaxants, particularly rocuronium, with promptly and completely reverse of deep neuromuscular block (NMB), which allows better surgical conditions. Sugammadex exhibits advantages over indirect
Hsiao-Cheng Chang, Shih-Yuan Liu, Min-Jia Lee, Sing-Ong Lee, Chih-Shung Wong   +4 more
doaj   +1 more source

Optimization of Bronchodilator Treatment in COPD: A Comparison of the Glycopyrrolate/Formoterol Combination vs. Formoterol Alone [PDF]

Kirkuk Journal of Medical Sciences
Background: Using a glycopyrrolate/formoterol combination to manage COPD patients is considered a new method. The objectives of this study are to evaluate the effectiveness of the glycopyrrolate/formoterol combination against formoterol alone in ...
Hiwa Saber, Ahmed Abdullah
doaj   +1 more source

Maternal hemodynamic effect of prophylactic glycopyrrolate after spinal anaesthesia for elective caesarean section [PDF]

, 2021
Introduction: Hypotension and bradycardia are the most common complications during spinal anesthesia. Bradycardia decreases cardiac output, resulting in hypotension and even cardiac arrest. Glycopyrronium, an anticholinergic drug increases heart rate and
Shrestha, Anil, Ghimire, Binam, Piya, Roshan, Amatya, Sirish Prasad, Hirachan, Niroj, Pradhan, Manisha   +5 more
core