Results 171 to 180 of about 116,862 (285)

Dual‐Pedicle Tissue‐Engineered Trachea Promotes Biomimetic Cartilaginous Framework, Vascularization, and Epithelial Lining for Long‐Segment Tracheal Reconstruction

Advanced Science, EarlyView.
Overcoming the limitations of conventional grafts, a biomimetic trachea with two independent vascular pedicles enables rapid integration and sustained patency. This approach markedly improves survival rates, restores the epithelial barrier, and promotes regenerative pathways, presenting a transformative paradigm for clinical application.
Ziming Wang, Yuming Wang, Zihao Chen, Erji Gao, Liang Guo, Juanjuan Li, Siqiang Zheng, Jiaoyu Yi, Zhe‐Sheng Chen, Bo Tao   +9 more
wiley   +1 more source

Engineered RNA Devices for In Vivo Targeted Therapeutics via Advanced Delivery Systems

Aggregate, EarlyView.
Schematic illustration of engineered RNA devices for in vivo targeted therapeutics via advanced delivery systems. ABSTRACT Engineered RNA devices can identify disease‐specific markers and precisely regulate gene expression, which is of great significance to the development of precision medicine.
Wei Luo, Xia Liu, Ying Han, Yijing Duan, Chuao Yu, Na Kong, Tian Xie   +6 more
wiley   +1 more source

circNR3C2 promotes chondrogenic differentiation and cartilage repair of human adipose‐derived stem cells via the hsa‐miR‐647/SOX9 pathway

Animal Models and Experimental Medicine, EarlyView.
The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou, Huajun Wang, Hao Guo, Dongbin Luo, Xiaofei Zheng, Simin Luo   +5 more
wiley   +1 more source

Glycosaminoglycans Prevent Induction of Fragmentation of Porcine Oocytes Stimulated by Dibutyryl Cyclic Adenosine 3 ,5- Monophosphate in Culture.

, 1994
Eimei Sato, Maki Inoue, Yūji Takahashi, Yutaka Toyoda   +3 more
openalex   +2 more sources

Expression of Glycosaminoglycan-Related Genes and the Role of Polyamines in the Glycosaminoglycan Biosynthetic Pathways

, 2020
Kyohei Higashi
openalex   +2 more sources

Effect of Diabetes on the Glycosaminoglycan Component of the Human Glomerular Basement Membrane [PDF]

, 1982
Narayanan Parthasarathy, Robert G. Spiro
openalex   +1 more source

Safety and efficacy of laronidase in Chinese patients with mucopolysaccharidosis type I: a phase IV, single-arm, open-label, multicenter study. [PDF]

Orphanet J Rare Dis
Liang Y, Yang YL, Zou CC, Liu L, Jiao Y, Wang Y, Liu X, Luo XP.   +7 more
europepmc   +1 more source

Integrating Cartilage Explant Culture with Simulated Digestion and Hepatic Biotransformation Refines In Vitro Screening of Joint Care Nutraceuticals. [PDF]

Methods Protoc
Crosbie M, Vanderboom K, Souccar-Young J, Pearson W.   +3 more
europepmc   +1 more source

Ulvan‐Based Electrospun Nanofibres From Water Solutions: Process Conditions and Characterisations

Journal of Applied Polymer Science, EarlyView.
Ulvan‐based electrospun nanofibres. ABSTRACT Recently, marine biopolymers have attracted considerable attention due to their high biocompatibility and biodegradability, making them ideal candidates in biomedical fields such as wound care, drug delivery, and tissue engineering.
Jacopo Paini, Federica Zaccheria, Gianluca Ottolina, Claudia Vineis, Erica Savino, Alessio Varesano   +5 more
wiley   +1 more source

T Cell Activation Induces Synthesis of CD47 Proteoglycan Isoforms and Their Release in Extracellular Vesicles. [PDF]

Int J Mol Sci
Kaur S, Kuznetsova SA, Sipes JM, Singh SP, Villasmil R, Roberts DD.   +5 more
europepmc   +1 more source