Results 181 to 190 of about 88,458 (304)

A sulfated chitosan-driven immune-ECM reprogramming strategy to break the vicious cycle of aged wound healing. [PDF]

Bioact Mater
Zhang X, Wang S, Liu Y, Wang J, Liu C.
europepmc   +1 more source

Glycosaminoglycan [PDF]

, 2020
openaire   +1 more source

Soil‐derived, gut‐dominant generalist bacteria shape the fitness of folivorous larvae

iMeta, EarlyView.
Whether Lepidoptera harbor a conserved core gut microbiome has long remained contentious. Through large‐scale microbiome profiling of folivorous larvae, their host plants, and associated soils across three climatically distinct regions of China, we identify two soil‐derived generalist bacteria, Ralstonia insidiosa and Delftia sp., that colonize 97.92 ...
Yu‐xuan Zheng, Ying Wang, Xiao‐man Zhang, Qian Jin, Yan Zhang, Gui‐fang Wang, Yong‐qi Shao, Jing Li, Cheng Sun, Wei‐dong Kong, Cai‐qing Yang, Ai‐bing Zhang   +11 more
wiley   +1 more source

Proteoglycans as Molecular Regulators of Bone Metastasis: Extracellular Matrix Remodeling, Tumor-Bone Crosstalk, Dormancy, and Therapeutic Opportunities. [PDF]

Biomolecules
Mora Guzmán Z, Salvador Ibarra IJ, Juárez P, Borrás Enríquez AJ, Díaz García EJ, Cabrera-Fuentes HA, Hernández-Huerta MT.   +6 more
europepmc   +1 more source

Sel1l preserves condylar cartilage matrix homeostasis by regulating PERK signaling

Interdisciplinary Medicine, EarlyView.
Our study revealed that the expression of Sel1l was downregulated in OA cartilage and that Sel1l deficiency induced cartilage catabolism. Mechanistically, Sel1l depletion aberrantly activated PERK signaling and resulted in ER stress. PERK inhibition rescued the phenotype of Sel1l‐deficient chondrocytes and alleviated TMJOA pathogenesis.
Xinqi Huang, Zinan Cen, Zhihe Zhao, Xiao Cen   +3 more
wiley   +1 more source

Mapping Sanfilippo Syndrome: A Multisystem Clinicopathological Autopsy. [PDF]

Diagnostics (Basel)
Trandafirescu MF, Avădănei ER, Filip N, Saveanu CI, Foia I, Toma V, Baroi LG, Anton-Paduraru DT, Moisa SM, Lozneanu L.   +9 more
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Proteomic stratification reveals immune metabolic heterogeneity in lung adenocarcinoma. [PDF]

Discov Oncol
Wang Y, Miao M, Wang Q, Yin Y, Zhao H, Zhao S, Yang H, Xiao T, Wang X.   +8 more
europepmc   +1 more source

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu, Xiao‐Bo Wan, Yong‐Shun Liang, Tian Lan, Hao Liang   +4 more
wiley   +1 more source

Histochemical and Semi-Quantitative Evidence of Dimoxystrobin-Induced Liver Extracellular Matrix Remodelling in Adult Zebrafish. [PDF]

J Xenobiot
Olivito I, Basile V, Graziani APM, Gharbi N, Macirella R.   +4 more
europepmc   +1 more source