Results 221 to 230 of about 72,922 (258)

Glycosaminoglycan microarrays for studying glycosaminoglycan–protein systems

Carbohydrate Polymers
More than 3000 proteins are now known to bind to glycosaminoglycans (GAGs). Yet, GAG-protein systems are rather poorly understood in terms of selectivity of recognition, molecular mechanism of action, and translational promise. High-throughput screening (HTS) technologies are critically needed for studying GAG biology and developing GAG-based ...
John E, Chittum, Ally, Thompson, Umesh R, Desai   +2 more
openaire   +2 more sources

Therapeutic Applications of Glycosaminoglycans

Current Medicinal Chemistry, 2006
Complex polysaccharides, hyaluronic acid or hyaluronan (HA), keratan sulfate (KS), chondroitin sulfates (CSs) and heparin (Hep)/heparan sulfate (HS), are a class of ubiquitous molecules exhibiting a wide range of biological functions. They are widely distributed as glycosaminoglycans (GAGs) sidechains of proteoglycans (PGs) in the extracellular matrix ...
openaire   +2 more sources

Spectrophotometric Method for the Assay of Glycosaminoglycans and Glycosaminoglycan-Depolymerizing Enzymes

Analytical Biochemistry, 1993
Undegraded glycosaminoglycans form a complex with 1-ethyl-2-[3-(1-ethylnaphtho-[1,2-d]thiazolin-2-ylidene)-2- methylpropenyl]naphtho-[1,2-d]thiazolium bromide (Stains-all) in solution resulting in a characteristic shift in spectrum. Hyaluronic acid (a nonsulfated glycosaminoglycan) reacts with the dye to form a complex with an absorbance maximum at 650
K A, Homer, L, Denbow, D, Beighton
openaire   +2 more sources

Capillary electrophoresis for the analysis of glycosaminoglycans and glycosaminoglycan‐derived oligosaccharides

Biomedical Chromatography, 2002
AbstractGlycosaminoglycans are a family of polydisperse, highly sulfated complex mixtures of linear polysaccharides that are involved in many life processes. Defining the structure of glycosaminoglycans is an important factor in elucidating their structure–activity relationship.
Wenjun, Mao, Charuwan, Thanawiroon, Robert J, Linhardt   +2 more
openaire   +2 more sources

Structural characterization and anticoagulant analysis of the novel branched fucosylated glycosaminoglycan from sea cucumber Holothuria nobilis

Carbohydrate Polymers, 2021
Sujuan Li, Lutan Zhou, Qinghua Cui
exaly  

Anticoagulant and anti-inflammatory effects of a degraded sulfate glycosaminoglycan from swimming bladder

Food Research International, 2022
Xuejing Jia, Bingbing Song, Saiyi Zhong   +2 more
exaly  

Sulfotransferases in glycosaminoglycan biosynthesis

Current Opinion in Structural Biology, 2003
Marion Kusche-Gullberg
exaly  

Glycosaminoglycan

2006
  +5 more sources

Diversity and functions of glycosaminoglycan sulfotransferases

Biochimica Et Biophysica Acta - General Subjects, 2000
Osami Habuchi
exaly  

A novel glycosaminoglycan-like polysaccharide from abalone Haliotis discus hannai Ino: Purification, structure identification and anticoagulant activity

International Journal of Biological Macromolecules, 2011
Guoyun Li, Shiguo Chen, Yuming Wang
exaly