Results 221 to 230 of about 90,028 (262)

Radiation‐Induced Skin Injury in Cancer Radiotherapy: From Mechanisms to Management

Advanced Oncology, Volume 1, Issue 1, December 2026.
Radiation‐induced skin injuries (RISI) remain a significant challenge faced by cancer patients receiving radiotherapy (RT). This perspective article examines the pathophysiology of RISI and evaluates the currently existing and emerging therapeutic strategies, including stem cell‐derived exosomes and advanced hydrogels.
Zeynep Meral Toutoungi, Nukhet Aykin‐Burns, Jingyi Chen, Younghye Song   +3 more
wiley   +1 more source

High Spinal Cord Injury After a Minor Fall in a 23-Month-Old Girl With Atlantoaxial Instability Associated With Morquio Type A: A Case Report. [PDF]

Case Rep Surg
Kryssi V, Syvänen J, Helenius L, Raitio A, Helenius I.   +4 more
europepmc   +1 more source

4‐Methylumbelliferone Restores Age‐Related Changes in Perineuronal Nets, Memory, and Neuroinflammation

Glia, Volume 74, Issue 12, December 2026.
Brain aging alters perineuronal nets and neuroinflammation. 4‐methylumbelliferone reversed these aging‐associated changes. 4‐methylumbelliferone reduced age‐associated cognitive decline. Six months of chronic oral treatment was well tolerated. ABSTRACT Aging‐associated cognitive decline is closely linked to dysregulated glial activity and chronic ...
Anda Cimpean, Jana Mizerakova, Noelia Martinez‐Varea, Dana Marekova, Lucia Machova Urdzikova, James W. Fawcett, Pavla Jendelova, Jessica C. F. Kwok   +7 more
wiley   +1 more source

Evaluation of a Micronized Collagen Wound Matrix for Advanced Wound Management: Physical, Structural and Biochemical Properties. [PDF]

Wound Repair Regen
Nasrallah RA, Alhamdi JR, Ngo TE, Avery JT, Kimmerling KA, Mowry KC.   +5 more
europepmc   +1 more source

Characterization of Lysosomal Hydrolases and Transporters and Their Age‐Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs

Clinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1338-1347, November 2026.
Lysosomes play a key role in the accumulation, catabolism, and transport of endogenous and exogenous metabolites and proteins and are involved in drug metabolism and prodrug activation. However, the protein abundance and interindividual variability of lysosomal drug‐metabolizing enzymes and transporters (DMETs) remain underexplored.
Darshak Gadara, Dilip Kumar Singh, Sandhya Subash, Guihua Yue, Deepak Ahire, Chris Bohl, Maciej Czerwinski, Stephanie Helmstetter, Scott Heyward, Robert S. Jones, Cyrus Khojasteh, Ryota Kikuchi, Priyanka Kulkarni, Bin Ma, Bernard Murray, Chris Seib, Bill Smith, David M. Stresser, Mitchell E. Taub, Ting Wang, Bhagwat Prasad   +20 more
wiley   +1 more source

The Self-amplifying Inflammatory Cascade in Obstetric Antiphospholipid Syndrome: From Pathophysiology to Placenta-centric Immunotherapeutic Targets. [PDF]

Clin Rev Allergy Immunol
Yan R, Wei Y, Chen L, Zhu S, Dong X.
europepmc   +1 more source

Articular Cartilage‐Derived Extracellular Matrix Material Promotes a Pro‐Regenerative Macrophage Phenotype to Support Chondrogenesis

Journal of Biomedical Materials Research Part A, Volume 114, Issue 11, November 2026.
ABSTRACT Articular cartilage (AC) repair remains a major clinical challenge due to its limited healing capacity and the inability of current treatment strategies to restore long‐term function. Biomaterial‐based strategies which support favorable immune responses and appropriate progenitor cell function have shown promise in enhancing cartilage ...
Sinead A. O'Rourke, Giovanni Gonnella, Gabriela S. Kronemberger, Stéphane Petrousek, David A. Hoey, Aisling Dunne, Daniel J. Kelly   +6 more
wiley   +1 more source

Aligned fibrous scaffolds containing glycosaminoglycan mimetics enhance Schwann cell-supported axon growth and myelination. [PDF]

J Neural Eng
Hashemi S, Chowdhury SSJ, Kylat A, Bunge MB, Oudega M, Arinzeh TL.   +5 more
europepmc   +1 more source

Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno, Laura Cinque, Viviana Cetrangolo, Chiara De Leonibus   +3 more
wiley   +1 more source

Secondary-Ion Mass Spectrometry Analysis of Pentosan Polysulfate. [PDF]

ACS Omega
Hook AL, Kotowska AM, Williams HEL, Wondraczek H.   +3 more
europepmc   +1 more source