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The glycosaminoglycans of open wounds

Journal of Surgical Research, 1980
Abstract Histochemical methods and selective enzymatic digestions were used to study the time course and location of specific glycosaminoglycans in open rabbit wounds. Hyaluronic acid seems to be increased in whole edge tissue, which may account for wound contraction and epithelial migration.
R. Bruce Donoff, Stanley A. Alexander
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Glycosaminoglycans

2010
Publisher Summary Glycosaminoglycans (GAGs) are a family of highly sulfated, complex, polydisperse linear polysaccharides that display a variety of important biological roles. Based on the difference of repeating disaccharide units comprising GAGs, they can be categorized into four main groups: heparin/heparan sulfate, chondroitin sulfate/dermatan ...
Zhenqing Zhang   +2 more
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Glycosaminoglycans in lung carcinoma

Human Pathology, 1988
In order to better understand the chemical composition of carcinomas of the lung, glycosaminoglycans (GAGs) of lung tumors from 34 patients were studied histochemically and quantitated spectrophotometrically. When the GAG quantity in neoplastic tissue was compared with that in normal lung tissue, total GAG contents in various carcinomas of the lung ...
Minoru Suzuki   +2 more
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Serpin–Glycosaminoglycan Interactions

2011
Serpins (serine protease inhibitors) have traditionally been grouped together based on structural homology. They share common structural features of primary sequence, but not all serpins require binding to cofactors in order to achieve maximal protease inhibition. In order to obtain physiologically relevant rates of inhibition of target proteases, some
Chantelle M. Rein   +2 more
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Spectrophotometric Method for the Assay of Glycosaminoglycans and Glycosaminoglycan-Depolymerizing Enzymes

Analytical Biochemistry, 1993
Undegraded glycosaminoglycans form a complex with 1-ethyl-2-[3-(1-ethylnaphtho-[1,2-d]thiazolin-2-ylidene)-2- methylpropenyl]naphtho-[1,2-d]thiazolium bromide (Stains-all) in solution resulting in a characteristic shift in spectrum. Hyaluronic acid (a nonsulfated glycosaminoglycan) reacts with the dye to form a complex with an absorbance maximum at 650
L. Denbow, K.A. Homer, D. Beighton
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Glycosaminoglycans and mucopolysaccharidoses

1996
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Jong, J.G.N. de   +4 more
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Glycosaminoglycan-based hydrogels capture inflammatory chemokines and rescue defective wound healing in mice

Science Translational Medicine, 2017
Nadine Lohmann   +8 more
semanticscholar   +1 more source

Glycosaminoglycans in human diabetes.

Diabete & metabolisme, 1983
The serum concentrations of different glycosaminoglycan fractions have been studied in diabetic subjects without evidence of vascular complications and compared with those of age-and sex-matched normal subjects. Electrophoretic analysis of the various glycosaminoglycan fractions showed an increase in hyalunoric acid and heparin, and a decrease in ...
CERIELLO A   +5 more
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Specificity of glycosaminoglycan-protein interactions.

Current Opinion in Structural Biology, 2018
L. Kjellén, U. Lindahl
semanticscholar   +1 more source

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