Results 301 to 310 of about 120,166 (348)

SYNTHESIS OF GLYCOSAMINOGLYCANS

Journal of Carbohydrate Chemistry, 2001
AbstractFor Abstract see ChemInform Abstract in Full Text.
Bryan K. S. Yeung, Pek Y. C. Chong, Peter A. Petillo   +2 more
openaire   +1 more source

Glycosaminoglycan microarrays for studying glycosaminoglycan–protein systems

Carbohydrate Polymers
More than 3000 proteins are now known to bind to glycosaminoglycans (GAGs). Yet, GAG-protein systems are rather poorly understood in terms of selectivity of recognition, molecular mechanism of action, and translational promise. High-throughput screening (HTS) technologies are critically needed for studying GAG biology and developing GAG-based ...
John E, Chittum, Ally, Thompson, Umesh R, Desai   +2 more
openaire   +2 more sources

Controversial glycosaminoglycan conformations

Nature, 1986
B, Casu, J, Choay, D R, Ferro, G, Gatti, J C, Jacquinet, M, Petitou, A, Provasoli, M, Ragazzi, P, Sinay, G, Torri   +9 more
exaly   +3 more sources

Glycosaminoglycans as polyelectrolytes

Advances in Colloid and Interface Science, 2010
One of the barriers to understanding structure-property relations for glycosaminoglycans has been the lack of constructive interplay between the principles and methodologies of the life sciences (molecular biology, biochemistry and cell biology) and the physical sciences, particularly in the field of polyelectrolytes.
Seyrek, E, Dubin, P
openaire   +2 more sources

Microanalysis of glycosaminoglycans

Analytical Biochemistry, 1981
Abstract A sensitive and versatile method for the qualitative and quantitative determination of glycosaminoglycans (GAGs) is described. An enriched GAG fraction was subjected to nuclease enzyme treatment and to an appropriate sequence of GAG degrading enzymes—Streptomyces hyaluronidase, chondroitinase AC and ABC, and endo-β- d -galactosidase—and ...
M, Breen, P A, Knepper, H G, Weinstein, L J, Blacik, D G, Lewandowski, B M, Baltrus   +5 more
openaire   +2 more sources

Glycosaminoglycan-lipoprotein interaction

Glycoconjugate Journal, 2001
Glycosaminoglycans (GAGs) bound to various proteoglycans (PGs) present in the cardiovascular system have been proposed to perform a wide range of functions. These include conferring viscoelastic properties; interacting with and modulating growth factors and enzymes; and as receptors and co-receptors in lipoprotein metabolism.
U, Olsson, G, Ostergren-Lundén, J, Moses   +2 more
openaire   +2 more sources

Glycosaminoglycans and Neuroprotection

2011
Glycosaminoglycans (GAGs) are basic building blocks of the ground substance of the extracellular matrix and present at the cellular level as an important component of the glycocalyx covering the cell membrane. In addition to the general role of GAGs in maintaining the integrity of the cell and extracellular matrix by retaining water, certain GAGs ...
B, Dudas, K, Semeniken
openaire   +2 more sources

Serpin–Glycosaminoglycan Interactions

2011
Serpins (serine protease inhibitors) have traditionally been grouped together based on structural homology. They share common structural features of primary sequence, but not all serpins require binding to cofactors in order to achieve maximal protease inhibition. In order to obtain physiologically relevant rates of inhibition of target proteases, some
Chantelle M, Rein, Umesh R, Desai, Frank C, Church   +2 more
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Glycosaminoglycans in Neurofibromas

The Journal of Dermatology, 1990
AbstractGlycosaminoglycan (GAG) contents in neurofibromas (NFs) were examined to clarify how well they corresponded to their histological features. Eight cutaneous NFs and three plexiform NFs from five patients with Recklinghausen's (R) disease, two senile NFs, and control dermis were subjected to the isolation of GAGs.
T, Sasaki, S, Onodera
openaire   +2 more sources

Glycosaminoglycans in Urolithiasis

Nephron, 1992
To determine if there are differences in urinary glycosaminoglycan (GAG) concentrations, 43 stone-forming patients and 37 healthy control subjects of both sexes were studied. Urinary concentrations of calcium, magnesium, creatinine, uric acid and GAGs were determined.
A, Nesse, G, Garbossa, M C, Romero, C E, Bogado, J R, Zanchetta   +4 more
openaire   +2 more sources