Results 331 to 340 of about 85,742 (348)
Some of the next articles are maybe not open access.
Glycosaminoglycans in Urolithiasis
Nephron, 1992To determine if there are differences in urinary glycosaminoglycan (GAG) concentrations, 43 stone-forming patients and 37 healthy control subjects of both sexes were studied. Urinary concentrations of calcium, magnesium, creatinine, uric acid and GAGs were determined.
Alcira Nesse +4 more
openaire +3 more sources
New targets for glycosaminoglycans and glycosaminoglycans as novel targets
Expert Review of Proteomics, 2013Biological functions of a variety of proteins are mediated via their interaction with glycosaminoglycans (GAGs). The structural diversity within the wide GAG landscape provides individual interaction sites for a multitude of proteins involved in several pathophysiological processes.
Tiziana Adage +4 more
openaire +2 more sources
Brain glycosaminoglycans and glycosaminoglycan sulphotransferase in sanfilippo syndrome
Clinica Chimica Acta, 1970Analysis of various glycosaminoglycans in brain obtained from two patients with Sanfilippo syndrome indicates that the major glycosaminoglycan accumulated in brain was heparan sulphate. Dermatan sulphate was also increased in one case as compared to normal, whereas only heparan sulphate was present in the other. Chondroitin-4-sulphate sulphotransferase
Bimal K. Bachhawat, Elizabeth George
openaire +3 more sources
Biomedical Chromatography, 2002
AbstractGlycosaminoglycans are a family of polydisperse, highly sulfated complex mixtures of linear polysaccharides that are involved in many life processes. Defining the structure of glycosaminoglycans is an important factor in elucidating their structure–activity relationship.
Wenjun Mao +2 more
openaire +3 more sources
AbstractGlycosaminoglycans are a family of polydisperse, highly sulfated complex mixtures of linear polysaccharides that are involved in many life processes. Defining the structure of glycosaminoglycans is an important factor in elucidating their structure–activity relationship.
Wenjun Mao +2 more
openaire +3 more sources
Therapeutic Applications of Glycosaminoglycans
Current Medicinal Chemistry, 2006Complex polysaccharides, hyaluronic acid or hyaluronan (HA), keratan sulfate (KS), chondroitin sulfates (CSs) and heparin (Hep)/heparan sulfate (HS), are a class of ubiquitous molecules exhibiting a wide range of biological functions. They are widely distributed as glycosaminoglycans (GAGs) sidechains of proteoglycans (PGs) in the extracellular matrix ...
openaire +3 more sources
Glycosaminoglycans in infectious disease
Biological Reviews, 2013ABSTRACTGlycosaminoglycans (GAGs) are complex carbohydrates that are ubiquitously present on the cell surface and in the extracellular matrix. Interactions between GAGs and pathogens represent the first line of contact between pathogen and host cell and are crucial to a pathogen's invasive potential. Their complexity and structural diversity allow GAGs
Robert J. Linhardt +3 more
openaire +3 more sources
Sulfotransferases in glycosaminoglycan biosynthesis
Current Opinion in Structural Biology, 2003Most of the sulfotransferases participating in glycosaminoglycan biosynthesis have now been identified. Their essential role in generating binding sites for proteins interacting with glycosaminoglycans is apparent. These interactions may influence important biological processes such as growth control, signal transduction, cell adhesion and lipid ...
Marion Kusche-Gullberg, Lena Kjellén
openaire +3 more sources
Analytical Biochemistry, 1993
Undegraded glycosaminoglycans form a complex with 1-ethyl-2-[3-(1-ethylnaphtho-[1,2-d]thiazolin-2-ylidene)-2- methylpropenyl]naphtho-[1,2-d]thiazolium bromide (Stains-all) in solution resulting in a characteristic shift in spectrum. Hyaluronic acid (a nonsulfated glycosaminoglycan) reacts with the dye to form a complex with an absorbance maximum at 650
L. Denbow, K.A. Homer, D. Beighton
openaire +3 more sources
Undegraded glycosaminoglycans form a complex with 1-ethyl-2-[3-(1-ethylnaphtho-[1,2-d]thiazolin-2-ylidene)-2- methylpropenyl]naphtho-[1,2-d]thiazolium bromide (Stains-all) in solution resulting in a characteristic shift in spectrum. Hyaluronic acid (a nonsulfated glycosaminoglycan) reacts with the dye to form a complex with an absorbance maximum at 650
L. Denbow, K.A. Homer, D. Beighton
openaire +3 more sources
2010
Publisher Summary Glycosaminoglycans (GAGs) are a family of highly sulfated, complex, polydisperse linear polysaccharides that display a variety of important biological roles. Based on the difference of repeating disaccharide units comprising GAGs, they can be categorized into four main groups: heparin/heparan sulfate, chondroitin sulfate/dermatan ...
Zhenqing Zhang +2 more
openaire +2 more sources
Publisher Summary Glycosaminoglycans (GAGs) are a family of highly sulfated, complex, polydisperse linear polysaccharides that display a variety of important biological roles. Based on the difference of repeating disaccharide units comprising GAGs, they can be categorized into four main groups: heparin/heparan sulfate, chondroitin sulfate/dermatan ...
Zhenqing Zhang +2 more
openaire +2 more sources
The glycosaminoglycans of open wounds
Journal of Surgical Research, 1980Abstract Histochemical methods and selective enzymatic digestions were used to study the time course and location of specific glycosaminoglycans in open rabbit wounds. Hyaluronic acid seems to be increased in whole edge tissue, which may account for wound contraction and epithelial migration.
R. Bruce Donoff, Stanley A. Alexander
openaire +3 more sources