Results 1 to 10 of about 87,711 (206)

Glycosaminoglycans and Proteoglycans

open access: yesPharmaceuticals, 2018
In this editorial to MDPI Pharmaceuticals special issue “Glycosaminoglycans and Proteoglycans” we describe in outline the common structural features of glycosaminoglycans and the characteristics of proteoglycans, including the intracellular proteoglycan,
Vitor H. Pomin, Barbara Mulloy
doaj   +2 more sources

Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all mammalian cells and usually covalently attached to proteins, forming proteoglycans.
Morla, Shravan
core   +3 more sources

Decorating the Anammox House: Sialic Acids and Sulfated Glycosaminoglycans in the Extracellular Polymeric Substances of Anammox Granular Sludge

open access: yesEnvironmental Science & Technology, 2020
Anammox (anaerobic ammonium oxidation) bacteria are important for the nitrogen cycle in both natural environments and wastewater treatment plants. These bacteria have a strong tendency to grow in aggregates like biofilms and granular sludge.
Marissa Boleij   +2 more
exaly   +2 more sources

Glycosaminoglycans in Tissue Engineering: A Review

open access: yesBiomolecules, 2020
Glycosaminoglycans are native components of the extracellular matrix that drive cell behavior and control the microenvironment surrounding cells, making them promising therapeutic targets for a myriad of diseases.
Harkanwalpreet Sodhi, Alyssa Panitch
doaj   +2 more sources

Medical application of glycosaminoglycans: a review

open access: yesJournal of Tissue Engineering and Regenerative Medicine, 2018
The characteristic molecular composition of the different glycosaminoglycans (GAGs) is related to their role as structural components and regulators of a multitude of functions of proteins, cells and tissues in the human body.
Thomas Groth
exaly   +2 more sources

The Effect of Glycosaminoglycans (GAGs) on Amyloid Aggregation and Toxicity

open access: yesMolecules, 2015
Amyloidosis is a protein folding disorder in which normally soluble proteins are deposited extracellularly as insoluble fibrils, impairing tissue structure and function.
Clara Iannuzzi   +2 more
doaj   +2 more sources

Chemokines and glycosaminoglycans

open access: yesFrontiers in Immunology, 2015
Although it was not known at the time, the chemokine field started with the identification of a protein by Heparin Sepharose affinity chromatography, platelet factor 4 (PF4) (1) now called CXCL4 in the systemic nomenclature introduced in 2000.
Amanda E.I. Proudfoot
doaj   +2 more sources

Operation spinal cord regeneration: Patterning information residing in extracellular matrix glycosaminoglycans

open access: yesBrain and Behavior, 2020
Introduction Spinal cord injuries are devastating, with many complications beyond paralysis and loss of sensory function. Although spinal cord regeneration can revolutionize treatment for spinal cord injuries, the goal has not yet been achieved.
Peng Sun
exaly   +2 more sources

Human milk glycosaminoglycans: the state of the art and future perspectives

open access: yesItalian Journal of Pediatrics, 2013
Recently, a complete characterization and detailed evaluation of the glycosaminoglycans of human milk were performed. The total glycosaminoglycans content in milk from healthy mothers having delivered term or preterm newborns showed a constant pattern ...
Coppa Giovanni Valentino   +10 more
doaj   +2 more sources

Glycosaminoglycans enhance osteoblast differentiation of bone marrow derived human mesenchymal stem cells

open access: yesJournal of Tissue Engineering and Regenerative Medicine, 2014
Extracellular matrix plays an important role in regulating cell growth and differentiation. The biomimetic approach of cell‐based tissue engineering is based on mirroring this in vivo micro environment for developing a functional tissue engineered ...
Suja Ann Mathew, Ramesh Bhonde
exaly   +2 more sources

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