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Glycosaminoglycans and Proteoglycans [PDF]
In this editorial to MDPI Pharmaceuticals special issue “Glycosaminoglycans and Proteoglycans” we describe in outline the common structural features of glycosaminoglycans and the characteristics of proteoglycans, including the intracellular proteoglycan,
Vitor H. Pomin, Barbara Mulloy
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Chemokines and glycosaminoglycans [PDF]
Although it was not known at the time, the chemokine field started with the identification of a protein by Heparin Sepharose affinity chromatography, platelet factor 4 (PF4) (1) now called CXCL4 in the systemic nomenclature introduced in 2000.
Amanda E.I. Proudfoot
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Pathogens that infect mammalian cells via sulfonated glycosaminoglycans [PDF]
Sulfonated glycosaminoglycans, such as heparan sulfate and dermatan sulfate, form major components of the cell surface and extracellular matrix, and display vital roles in mammalian physiology, including growth and development.
Jessica S. Morris, Paul A. Dawson
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Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation [PDF]
Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all mammalian cells and usually covalently attached to proteins, forming proteoglycans.
Shravan Morla
semanticscholar +4 more sources
Mast cell glycosaminoglycans [PDF]
Mast cells contain granules packed with a mixture of proteins that are released on degranulation. The proteoglycan serglycin carries an array of glycosaminoglycan (GAG) side chains, sometimes heparin, sometimes chondroitin or dermatan sulphate.
B. Mulloy, R. Lever, C. Page
semanticscholar +7 more sources
Glycosaminoglycans and infection. [PDF]
Glycosaminoglycans (GAGs) are complex linear polysaccharides expressed in intracellular compartments, at the cell surface, and in the extracellular environment where they interact with various molecules to regulate many cellular processes implicated in health and disease. Subversion of GAGs is a pathogenic strategy shared by a wide variety of microbial
R. S. Aquino, P. Park
semanticscholar +3 more sources
Glycosaminoglycans: What Remains To Be Deciphered?
Glycosaminoglycans (GAGs) are complex polysaccharides exhibiting a vast structural diversity and fulfilling various functions mediated by thousands of interactions in the extracellular matrix, at the cell surface, and within the cells where they have ...
S. Pérez +18 more
semanticscholar +1 more source
Glycosaminoglycans (GAGs) are important constituents of human glycome. They are negatively charged unbranched polysaccharides that are usually covalently attached to proteins, forming glycan-protein conjugates, called proteoglycans. Glycosaminoglycans play critical roles in numerous biological processes throughout individual development and are also ...
Yuefan, Song +2 more
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K. Balagurunathan, H. Nakato, U. Desai
semanticscholar +2 more sources

