Results 131 to 140 of about 85,805 (344)

The Effect of Heparin and Other Exogenous Glycosaminoglycans (GAGs) in Reducing IL-1β-Induced Pro-Inflammatory Cytokine IL-8 and IL-6 mRNA Expression and the Potential Role for Reducing Inflammation

open access: yesPharmaceuticals
Glycosaminoglycans (GAGs) are long linear polysaccharides found in every mammalian tissue. Previously thought only to be involved in cellular structure or hydration, GAGs are now known to be involved in cell signaling and protein modulation in cellular ...
Murtaza Jafri   +3 more
doaj   +1 more source

circNR3C2 promotes chondrogenic differentiation and cartilage repair of human adipose‐derived stem cells via the hsa‐miR‐647/SOX9 pathway

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou   +5 more
wiley   +1 more source

Therapeutic targeting of myeloid cells in liver fibrosis: Mechanisms and clinical prospects

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This review systematically summarizes the origin, recruitment, and differentiation regulation mechanisms of myeloid cells in driving hepatic fibrosis progression. By targeting these three critical phases, potential therapeutic strategies for liver fibrosis can be explored.
Yue Wang   +5 more
wiley   +1 more source

Time‐of‐Flight Secondary Ion Mass Spectrometry‐Partial Least Square Regression for Quantifying Interleukin‐8 in Biopolymer Matrices

open access: yesAdvanced NanoBiomed Research, EarlyView.
The power of time‐of‐flight secondary ion mass spectrometry‐partial least square regression to detect interleukin‐8, a chemokine involved in inflammation and cancer, down to mass fractions of 1 ppm within biopolymer matrices, including Matrigel and glycosaminoglycan‐based hydrogels, is demonstrated.
Ralf Zimmermann   +4 more
wiley   +1 more source

Sustainable Materials in 3D Printing: Exploring the Potential of Microalgae

open access: yesJournal of Applied Polymer Science, EarlyView.
Overview of 3D Printing: Exploring its application fields, key techniques, green and algal‐based materials, and future perspectives for sustainable innovation. ABSTRACT 3D printing has emerged as a key enabler of sustainable production, offering improved material efficiency and reduced waste. As bioprinting and the use of bio‐derived materials continue
Silvia Racioppi   +3 more
wiley   +1 more source

Evaluation of Poly(l‐Co‐d,l‐Lactic Acid‐Co‐Trimethylene Carbonate) Scaffolds Fabricated by 3D Printing and Leaching for Bone Tissue Engineering

open access: yesJournal of Applied Polymer Science, EarlyView.
Steps of fabrication and analysis of PLDLA‐TMC scaffolds obtained by 3D printing followed by a leaching process, designed for applications in bone tissue engineering. ABSTRACT Bone defect regeneration remains a complex clinical challenge, particularly in cases resulting from trauma, surgical procedures, congenital malformations, or tumor resections ...
Rover Martinez Clusella Delgado   +5 more
wiley   +1 more source

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