Results 141 to 150 of about 64,705 (285)

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

FlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu, Yubing Hu, Dong Wang, Ben Zhong Tang   +3 more
wiley   +1 more source

Engineering an artificial trachea: Quantitative benchmarks and modular strategies for mechanics, epithelialization, and vascular integration

FlexMat, EarlyView.
In this work, we first examine the limitations of surgical repair and stenting, including migration, granulation, mucus plugging, and infection. We then translate these failures into engineering constraints involving geometry, mechanics, fixation, degradation, junctional stress, and remodeling.
Yiwei Xu, Hanqing Dai, Qianwang Ye, Wanlu Zhang, Na Wang, Lei Xiong, Ruiqian Guo   +6 more
wiley   +1 more source

Fine characterization of mitral valve glycosaminoglycans and their modification with degenerative disease

, 2006
Fine characterization of mitral valve glycosaminoglycans and their modification with degenerative ...
VOLPI, Nicola, Barili, F, Porqueddu, M, MACCARI, Francesca, Dainese, L, Alamanni, F, Guarino, A, Biglioli, P., Polvani, Gl, Agrifoglio, M, Zanobini, M, Micheli, B   +11 more
core  

Oral Bacterial Extracellular Vesicles as Systemic Messengers: A Mouth–Gut–Systemic Axis Paradigm

Gut Medicine, EarlyView.
ABSTRACT Oral microbiome dysbiosis not only associated with localized periodontal disease but also with multiple systemic diseases, including cardiovascular disease, diabetes mellitus, Alzheimer's disease, rheumatoid arthritis, and cancer. However, the efficiency with which intact viable bacteria cross biological barriers to reach distant organs is ...
Yaping Huang, Narisu Hu, Shuang Pan, Sohaib Shujaat, Zhihui Tang, Hongyang Ma   +5 more
wiley   +1 more source

Heparan Sulfate, Chondroitin Sulfate, and Keratan Sulfate as Regulators of Tumor Malignancy. [PDF]

Int J Mol Sci
Ohkawa Y, Taniguchi N.
europepmc   +1 more source

Correction: Glycosaminoglycans and proteoglycans: emerging macromolecular targets in neuroinflammation and cognitive decline. [PDF]

3 Biotech
Goel F, Gupta P, Kartik S, Singh P, Rai SN.   +4 more
europepmc   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell‐Derived Exosomes Preserve Cartilage Homeostasis and Restore Joint Function in Experimental Osteoarthritis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mesenchymal stem cells (MSCs) have shown therapeutic potential for osteoarthritis (OA), but their clinical application is limited by the need for extensive ex vivo expansion. Human umbilical cord MSC‐derived exosomes (hUCMSC‐Exos) have emerged as a promising cell‐free alternative because of their cartilage‐protective and immunomodulatory ...
Sung‐Yen Lin, Yi‐Shan Lin, Shu‐Chun Chuang, Yi‐Wen Kuo, Cheng‐Jung Ho, Kai‐Hsuan Wang, Wei‐Cheng Tsai, Zhi‐Xiang Li, Wan‐Jung Lin, Yi‐Ju Hsieh, Chung‐Hwan Chen, Tzou‐Yien Lin   +11 more
wiley   +1 more source

Bioactive Glycosaminoglycans from <i>Caranx crysos</i>: A Structure-Function Study of Selective Anticoagulant Activity. [PDF]

Mar Drugs
Kroumi R, Alimi S, Esposito F, Haffouz A, Hadjkacem B, Casillo A, Haddar A, Sila A, Bedini E, Bougatef A.   +9 more
europepmc   +1 more source