Results 121 to 130 of about 53,525 (250)

Bioavailable human metabolites of a keratin-derived hydrolysate promote primary human dermal fibroblast activities and protect against oxidative stress-related damages. [PDF]

Front Nutr
Wauquier F, Boutin-Wittrant L, Soulard JP, Quinard RM, Sapin V, Roux V, Macian N, Pickering G, Wittrant Y.   +8 more
europepmc   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Glycosaminoglycans and Glioma Invasion

, 2014
There is a great need for novel therapiesto target malignant glioma, a disease withan often dismal prognosis. One of the hallmarksof malignant glioma is its effi cient invasion of thehealthy brain parenchyma, which leads to rapidlyrecurrent disease upon ...
Forsberg-Nilsson, Karin,, Kundu, Soumi,
core  

Sel1l preserves condylar cartilage matrix homeostasis by regulating PERK signaling

Interdisciplinary Medicine, EarlyView.
Our study revealed that the expression of Sel1l was downregulated in OA cartilage and that Sel1l deficiency induced cartilage catabolism. Mechanistically, Sel1l depletion aberrantly activated PERK signaling and resulted in ER stress. PERK inhibition rescued the phenotype of Sel1l‐deficient chondrocytes and alleviated TMJOA pathogenesis.
Xinqi Huang, Zinan Cen, Zhihe Zhao, Xiao Cen   +3 more
wiley   +1 more source

Influence of Propolis-Containing Nonwoven PLGA Dressings on Dermatan and Chondroitin Sulfate Dynamics During Burn-Wound Healing. [PDF]

Pharmaceuticals (Basel)
Orlińska K, Stojko M, Włodarczyk J, Kasperczyk J, Tasinov O, Ivanova D, Radeva MN, Janik P, Komosińska-Vassev K, Olczyk K, Stojko J, Olczyk P.   +11 more
europepmc   +1 more source

High urinary excretion of glycosaminoglycans: a possible marker of glomerular involvement in diabetes.

, 1989
Many insulin-dependent diabetic patients with albuminuria in the "not at risk range" for diabetic nephropathy present high urinary excretion rates of glycosaminoglycans.
Baggio B., Cicerello E, Lavagnini T, Mastrosimone S, Gambaro G   +4 more
core  

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

Interdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi, Min Chen, Yisheng Chen, MengYao Li, Jiale Ma, Zuozhen Yin, Li Wu, YangBao Miao, Zemin Ou, Ke Wu, Zhijie Xu, Lizhi Li, Shaocong Zhao, Shiwei He, Bin Huang, Guanwen He, Guanghui Wu, John H. Zhang, Liang Shi   +18 more
wiley   +1 more source

Advanced Molecular Imaging Probes for Skeletal Diseases: Current Progress and Future Perspectives

iRADIOLOGY, EarlyView.
This review summarizes the potential molecular imaging techniques and probes for common orthopedic diseases, such as trauma, infection, metabolism, tumor, joint, spine and other fields, aiming to provide a basis for the development of a new generation of molecular imaging probes.
Shuo Guo, Yuling Cui, Zhiye Fan, Chenxin Jiang, Bowen Fu, Guangbin Cui, Yanli He   +6 more
wiley   +1 more source

Going with the flow: endothelial dysfunction in type 2 diabetes. [PDF]

Function (Oxf)
Dunaway LS.
europepmc   +1 more source